Protein Alignment CALM3 and Mlc-c

DIOPT Version :10

• Sequence 1: NP_005175.2
• Gene: CALM3 / 808
• HGNCID: 1449
• Length: 149
• Species: Homo sapiens
• Sequence 2: NP_001245533.1
• Gene: Mlc-c / 31474
• FlyBaseID: FBgn0004687
• Length: 153
• Species: Drosophila melanogaster
• Alignment Length: 139
• Identity: 63/139 - (45%)
• Similarity: 94/139 - (67%)
• Gaps: 5/139 - (3%)

Human    10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTM-- 72
            :.||:|||:|||..|||.|...::|..:|:|||||||::::...:::..|..  |.|..||.:
  Fly    15 LEEFQEAFNLFDNRGDGKIQLSQVGECLRALGQNPTESDVKKCTHQLKPDER--ISFEVFLPIYQ 77

Human    73 MARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQV 137
            ...|.:..|:.::..|..|.||||.:||||:|||||::|.||||||||||::::...: |..|.:
  Fly    78 AISKARSGDTADDFIEGLRHFDKDASGYISSAELRHLLTTLGEKLTDEEVEQLLANME-DQQGNI 141

Human   138 NYEEFVQMM 146
            ||||||:|:
  Fly   142 NYEEFVRMV 150

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CALM3	NP_005175.2	PTZ00184	1..149	CDD:185504	63/139 (45%)
		Necessary and sufficient for interaction with PCP4. /evidence=ECO:0000269|PubMed:27876793	77..149		36/70 (51%)
Mlc-c	NP_001245533.1	PTZ00184	14..152	CDD:185504	63/139 (45%)