Protein Alignment PTP4A2 and PRL-1

DIOPT Version :10

• Sequence 1: NP_536316.1
• Gene: PTP4A2 / 8073
• HGNCID: 9635
• Length: 167
• Species: Homo sapiens
• Sequence 2: NP_609780.1
• Gene: PRL-1 / 34952
• FlyBaseID: FBgn0024734
• Length: 176
• Species: Drosophila melanogaster
• Alignment Length: 168
• Identity: 97/168 - (57%)
• Similarity: 123/168 - (73%)
• Gaps: 5/168 - (2%)

Human     3 RPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPF 67
            ||||..|.|:.|:||||..|::.|:|.:..||||..|.|:||||:.:|:...:|.:||.|.|..|
  Fly    11 RPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAF 75

Human    68 DDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQ 132
            :||..||.|:||:|..:||.|:::.|..|||||||||||||||||||||||.|:|||.||:.||.
  Fly    76 EDGTFPPQQVVDEWFEVLKDKYQQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRD 140

Human   133 KRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ 167
            |||||.|:|||.:||||:||.||:.:  |||   |.||
  Fly   141 KRRGAINAKQLSFLEKYKPKARLKHK--NGHKNSCSVQ 176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTP4A2	NP_536316.1	PTP-IVa2	1..155	CDD:350512	89/151 (59%)
PRL-1	NP_609780.1	PTP-IVa	10..163	CDD:350350	89/151 (59%)