Protein Alignment PBX4 and vis

DIOPT Version :10

• Sequence 1: XP_011526622.1
• Gene: PBX4 / 80714
• HGNCID: 13403
• Length: 391
• Species: Homo sapiens
• Sequence 2: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 155
• Identity: 41/155 - (26%)
• Similarity: 68/155 - (43%)
• Gaps: 22/155 - (14%)

Human   172 HV-TNLLQEQSRMRPVSPKEIER-MVGAIHGKFSAIQMQLKQSTCEAVMTLRSRLLDA------- 227
            || .:||..:.|.|..|...::: .:.|:.|...:.:....|     |......::|:
  Fly    29 HVHASLLNNEGRDRFHSDSSLDQDSLHAVVGNDLSTEQGANQ-----VQNYHDMMVDSEHHVDIN 88

Human   228 ---RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKNM 289
               |::|.|..|.:.::|..:.|.|..|.|||:..|..|:::..||:.||.|||.|.|.|....|
  Fly    89 GSLRKRRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEM 153

Human   290 GKFQEEATIY-----TGKTAVDTTE 309
            .:.:....::     .||..|..||
  Fly   154 IRREGNDPLHFTISRRGKKVVGATE 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PBX4	XP_011526622.1	PBC	18..226	CDD:461052	11/55 (20%)
		homeodomain	228..289	CDD:238039	23/60 (38%)
vis	NP_788337.1	Homeobox_KN	110..148	CDD:428673	17/37 (46%)