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Protein Alignment SHOC2 and scrib

DIOPT Version :9

Sequence 1:	NP_001311265.1	Gene:	SHOC2 / 8036	HGNCID:	15454	Length:	582	Species:	Homo sapiens
Sequence 2:	NP_001163746.1	Gene:	scrib / 44448	FlyBaseID:	FBgn0263289	Length:	2585	Species:	Drosophila melanogaster

Alignment Length:	395	Identity:	128/395 - (32%)
Similarity:	202/395 - (51%)	Gaps:	30/395 - (7%)

- Green bases have known domain annotations that are detailed below.

Human   169 KKLRMLDLRHNKLREIPSVVYRLD-SLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPA 232
            :::..:|.||..|.::|..:.|.. :|..|:|..|.|..:.|:...|.:|..|.:.:|:|.:||.
  Fly    13 RQVEFVDKRHCSLPQVPEEILRYSRTLEELFLDANHIRDLPKNFFRLHRLRKLGLSDNEIGRLPP 77

Human   233 EIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLS 297
            :|....||:.|||:.|.:..:|.:|.:...:...|...|.:..||.....|.:|:.|||....|:
  Fly    78 DIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLT 142

Human   298 AIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQ-LYPVGGPSQFSTIYSLN 361
            .:|......:.||.|.|..|.:..|||: :|.|.||..|.|..|..: |.|..|  ....::.|.
  Fly   143 TLPADFGSLTQLESLELRENLLKHLPET-ISQLTKLKRLDLGDNEIEDLPPYLG--YLPGLHELW 204

Human   362 MEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVS 426
            ::|                        |||..||.:.|..|.:..|:::.|:|.::|.::|||||
  Fly   205 LDH------------------------NQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVS 245

Human   427 LEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIG 491
            |..|.|:.|||:.||.|:..|.:|..|.|::|:|:.|.:.:...:::|:|:||.|.|:.||..||
  Fly   246 LTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIG 310

Human   492 HLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHL 556
            .:|.|.:|.:..|.|.:||.|||...||..|.|.|| .|..||.||..|:.|.::.:....|.:|
  Fly   311 QMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDN-KLKKLPPELGNCTVLHVLDVSGNQLLYL 374

Human   557 PPQIV 561
            |..:|
  Fly   375 PYSLV 379

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.