Protein Alignment PABPC1L and pab-1

DIOPT Version :9

• Sequence 1: NP_001359108.1
• Gene: PABPC1L / 80336
• HGNCID: 15797
• Length: 619
• Species: Homo sapiens
• Sequence 2: NP_001369814.1
• Gene: pab-1 / 172920
• WormBaseID: WBGene00003902
• Length: 646
• Species: Caenorhabditis elegans
• Alignment Length: 662
• Identity: 332/662 - (50%)
• Similarity: 420/662 - (63%)
• Gaps: 94/662 - (14%)

Human     2 NASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAE 66
            |.:||.|.:||||||||||||.|::|:||||.|||:||||||||.|||.||||||:|||||||||
 Worm    23 NQTGSSYTMASLYVGDLHPDVNESILFEKFSAAGPVLSIRVCRDNATRLSLGYAYVNFQQPADAE 87

Human    67 RALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
            ||:||||||.|.|:|:|||||||||.:|:||.||||||||:..||||::|||||.||||||||||
 Worm    88 RAMDTMNFEALHGKPMRIMWSQRDPAMRRSGAGNIFIKNLDKVIDNKSIYDTFSLFGNILSCKVA 152

Human   132 CDEHG-SRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYV 195
            .||.| |:|:|||||||.||||.||..:|||||..:|||||.|:.|.:|..|||..|.:|||:||
 Worm   153 IDEDGFSKGYGFVHFETEEAAQNAIQKVNGMLLAGKKVFVGKFQPRAQRNRELGETAKQFTNVYV 217

Human   196 KNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGR- 259
            ||.....:::.|:.||::||.:.|.:|| ...|.|:.||||.|...|||:.||..::...:.|.
 Worm   218 KNFGDHYNKETLEKLFAKFGNITSCEVM-TVEGKSKGFGFVAFANPEEAETAVQALHDSTIEGTD 281

Human   260 -LLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSA 323
             .|:..||||:.||..|||::.||.|.:|:::||||||||||||:::|||.|:|:|..||.||||
 Worm   282 LKLHVCRAQKKSERHAELKKKHEQHKAERMQKYQGVNLYVKNLDETVDDDGLKKQFESYGNITSA 346

Human   324 KVMT-EGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQRLS 387
            |||| |.|.|||||||||..|||||.||||||.::|.:||||||:|||||:|:|.|.:||||||:
 Worm   347 KVMTDENGRSKGFGFVCFEKPEEATSAVTEMNSKMVCSKPLYVAIAQRKEDRRAQLASQYMQRLA 411

Human   388 TMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAYYGCGPVTPTQPAP-RWTSQPPRPSSAYPPGAS 451
            :||...|                   .|..|.|      .||||.| .:.:.|.:....:..|..
 Worm   412 SMRMHGN-------------------VPGAAMY------NPTQPGPGYYVANPMQQQRNFAGGQQ 451

Human   452 MVRP----------PVV-------------------------PRRPPAHISSVRQASTQVPRTVP 481
            ||||          ||.                         ||.||...:.|.|...:: :..|
 Worm   452 MVRPGGRWGMQNQYPVQNQYMMAQGPGVYQNRMGRPQNQQGGPRGPPQQYNQVAQGGVRM-QGPP 515

Human   482 HTQRVANIGTQTTG------------PSGVGCCTPGRPLLPCKCSSAAHSTYRVQEPAVHIPGQE 534
            .||   |.|.|...            |:..|...|.:|          :..|:.:...:.|.|||
 Worm   516 RTQ---NPGVQQQNVPRPPQQQQQQRPAPTGPKAPPQP----------YQAYQQRPQGIVIGGQE 567

Human   535 PLTASMLAAAPLHEQKQMIGERLYPLIHDVHT--QLAGKITGMLLEIDNSELLLMLESPESLHAK 597
            |||::|||||...||||::|||:|.||..::.  :.|||||||:||||||||::||:..|...:|
 Worm   568 PLTSAMLAAAAPQEQKQLLGERIYALIEKLYPGHKDAGKITGMMLEIDNSELIMMLQDSELFRSK 632

Human   598 IDEAVAVLQAHQ 609
            :|||.:||.:.|
 Worm   633 VDEAASVLVSAQ 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PABPC1L	NP_001359108.1	PABP-1234	11..606	CDD:130689	326/648 (50%)
pab-1	NP_001369814.1	PABP-1234	32..640	CDD:130689	325/647 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	123	1.000	Domainoid score	I3805
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	631	1.000	Inparanoid score	I501
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53624
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	1	1.000	-	-		mtm5099
orthoMCL	1	0.900	-	-		OOG6_100425
Panther	1	1.100	-	-	LDO	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X269
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.980