Protein Alignment WNT10A and Wnt10

DIOPT Version :10

• Sequence 1: NP_079492.2
• Gene: WNT10A / 80326
• HGNCID: 13829
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_609109.4
• Gene: Wnt10 / 34011
• FlyBaseID: FBgn0031903
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 415
• Identity: 173/415 - (41%)
• Similarity: 242/415 - (58%)
• Gaps: 57/415 - (13%)

Human    56 NANTVCLTLPGLSRRQMEVCVRHPDVAASAIQGIQIAIHECQHQFRDQRWNCSSLETRNKIPYES 120
            :....|.::|||::.|:|:|.:..||.|:|::|:.:||.|||.||:..|||||||.|:::.|:.|
  Fly    81 DGRATCRSVPGLTKDQVELCYKASDVTAAALEGLDMAIRECQIQFQWHRWNCSSLSTKSRNPHAS 145

Human   121 PIFSRGFRESAFAYAIAAAGVVHAVSNACALGKLKACGCD--ASRRGDEEAFRRKLHRLQLDALQ 183
            .:..:|:||||||:||:||||.|:|:.||:.|:|.:||||  .:|:...:..|:.|.:.:...||
  Fly   146 SLLKKGYRESAFAFAISAAGVAHSVARACSQGRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQ 210

Human   184 RGKGLSHGVPEHPALPTASPGLQDSWEWGGCSPDMGFGERFSKDFLDSREPHRDIHARMRLHNNR 248
            ..:......||.......|. :...|:|||||.:|.||..:||.|||.||...||.:::.||||.
  Fly   211 YLETNQILTPEEEKKYERSK-IASRWKWGGCSHNMDFGVEYSKLFLDCREKAGDIQSKINLHNNH 274

Human   249 VGRQAVMENMRRKCKCHGTSGSCQLKTCWQVTPEFRTVGALLRSRFHRATLIRPHNRNGGQLEP- 312
            .||.||..||..:|||||.||||||||||:..|:|..||.:|:.:|.:|.|:...|...|  ||
  Fly   275 AGRIAVSNNMEFRCKCHGMSGSCQLKTCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNG--EPV 337

Human   313 ------------GPAGAPSPAP-------------GAPG---PRR----------RASPAD---- 335
                        |.:|:.|.:|             |..|   .||          |...||
  Fly   338 VVLKRARNKKSNGGSGSGSTSPDLDSTDASGGHDDGGTGDSETRRHDELGVERGTRQPSADKNAA 402

Human   336 ---------LVYFEKSPDFCEREPRLDSAGTVGRLCNKSSAGSDGCGSMCCGRGHNILRQTRSER 391
                     |.|:::||:||||:...|..|||||.||:::..||||.|:||||||:.:.|.|:||
  Fly   403 RMARKLETSLFYYQRSPNFCERDLGADIQGTVGRKCNRNTTTSDGCTSLCCGRGHSQVIQRRAER 467

Human   392 CHCRFHWCCFVVCEECRITEWVSVC 416
            |||:|.|||.|.||||.:.||:|:|
  Fly   468 CHCKFQWCCNVECEECHVEEWISIC 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT10A	NP_079492.2	Wnt	58..417	CDD:393294	173/413 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..331		12/69 (17%)
Wnt10	NP_609109.4	Wnt	83..493	CDD:393294	173/413 (42%)