Protein Alignment WNT10A and Wnt4

DIOPT Version :10

• Sequence 1: NP_079492.2
• Gene: WNT10A / 80326
• HGNCID: 13829
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Alignment Length: 364
• Identity: 111/364 - (30%)
• Similarity: 168/364 - (46%)
• Gaps: 71/364 - (19%)

Human    61 CLTLPGLSRRQMEVCVRHPDVAASAIQGIQIAIHECQHQFRDQRWNCSSLETRNKIPYESPIFSR 125
            |..:|. :|||...|.:...:..:..:..::|...|:.|||..|||| |:|||.|    ..||.:
  Fly   240 CRYMPA-TRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNC-SIETRGK----RNIFKK 298

Human   126 GFRESAFAYAIAAAGVVHAVSNACALGKLKACGCDASRRGDEEAFRRKLHRLQLDALQRGKGLSH 190
            .::|:||.:|:.||.:.|:::.|||.|::..|.|...:...|
  Fly   299 LYKETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKKHNRE----------------------- 340

Human   191 GVPEHPALPTASPGLQDSWEWGGCSPDMGFGERFSKDFLDSREPHRDIHARMRLHNNRVGRQAVM 255
                          .|| ::||||:.::..|:|.::.|||.|....|..:.:..|::.||.:||.
  Fly   341 --------------AQD-FQWGGCNDNLKHGKRVTRSFLDLRGGDGDEVSEILRHDSEVGIEAVS 390

Human   256 ENMRRKCKCHGTSGSCQLKTCWQVTPEFRTVGALLRSRFHRATLIRPHNRNGGQLEPGPAGAPSP 320
            ..|..||||||.||||.:||||:...:|.....|||.:::.|....|:.|:..|:.......|.
  Fly   391 SQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIRKAPNQRSMRQVSSSRMKKPK- 454

Human   321 APGAPGPRRRASP-----ADLVYFEKSPDFCEREPRLDSAGTVGRLCNKSSAGSDGCGSMCCGRG 380
                   :||..|     ..|.|.|.||.:|        |.|..|.|    ...|.||::|||||
  Fly   455 -------QRRKKPQQSQYTTLYYLETSPSYC--------AVTKDRQC----LHPDNCGTLCCGRG 500

Human   381 HNILRQTRSERCHCRFH--WCCFVVCEECRITEWVSVCK 417
            :......:.|:|.|||:  .||.::|:.|:..|....||
  Fly   501 YTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFCK 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT10A	NP_079492.2	Wnt	58..417	CDD:393294	109/362 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..331		5/30 (17%)
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	107/357 (30%)