Protein Alignment CCDC6 and CG6664

DIOPT Version :10

• Sequence 1: NP_005427.2
• Gene: CCDC6 / 8030
• HGNCID: 18782
• Length: 474
• Species: Homo sapiens
• Sequence 2: NP_648944.1
• Gene: CG6664 / 39903
• FlyBaseID: FBgn0036685
• Length: 532
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 240/540 - (44%)
• Similarity: 304/540 - (56%)
• Gaps: 135/540 - (25%)

Human    23 MQSSCSSTSGGGGGGGGGGGGGKSGGIVI--SPFRLEELTNRLASLQQENKVLKIELETYKLKCK 85
            |:|.|.|.|            ...||.::  ||...|:|..|:.||.|:|||||.||:|:|.|||
  Fly     1 MESPCESES------------SLDGGTMLPPSPVSREQLQKRIESLTQQNKVLKAELDTFKTKCK 53

Human    86 ALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLM 150
            .:|||||.|::|||.|||:||||||:|||||.||||||:|||||||.:||:|||.|||:|||||.
  Fly    54 VVQEENRCLKQASVIIQAKAEQEEEYISNTLLKKIQALKKEKETLAHHYEREEECLTNDLSRKLD 118

Human   151 QLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVN 215
            ||:.||.:|||.||||||..|||||:||:||:.:|.:||..|||||||.::||||||||||||||
  Fly   119 QLRQEKCKLEQTLEQEQECLVNKLMRKIEKLQAETDNKQTNLEQLRREMVELENTLEQEQEALVN 183

Human   216 RLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEI-----DSPENMMRHIRFLKNEVERLKKQ 275
            :|||||||||.|||.||.|||||||.|.:||||:...     |:..::..||:.|::||.|.:..
  Fly   184 KLWKRMDKLETEKRSLQIKLDQPVSDPTTPRDITNNAHANGGDTATSLSAHIQILRSEVLRYRSD 248

Human   276 LRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNE- 339
            |.:||.:.:.|..||.:||:.:||||.||||||::|:||||||||.|||||||||||:||::||
  Fly   249 LASAQKEATIKTQQYAQEEKSIREENARLQRKLKQEVERREALCRHLSESESSLEMDEERFYNEN 313

Human   340 --------------------MSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSY------------ 372
                                :|||  |.||:|||:.:  |||||||:|||.:.
  Fly   314 LMGGGSFAVATAAAAAAASAVSAQ--RQRTISSPVSH--SPSSSRPLSPGTAVQNRCYACGQLVN 374

Human   373 ----------------------ASHTVGFTPP--------TSLTRAGMSYYNSPGLHVQHMG--- 404
                                  |.:.:..|.|        :|.:.|.:|..|:.|..:.::|
  Fly   375 RRASERFIKPALPTPMLGLNTSAPNVLTSTNPLLGILGTGSSSSSASVSAGNAAGGFLSNLGGER 439

Human   405 ----------------------------TSHGITRPSPRR------------------SNSPDKF 423
                                        |||.....|...                  |||....
  Fly   440 LSLGSSNSAGGSATFLAGGGGGGLLAQLTSHSSASSSSSNLMNISLNNSSSGNLVNSSSNSSLSA 504

Human   424 KRPTPPPSPNTQTPVQPPPP 443
            ..||.|||......:||..|
  Fly   505 FTPTNPPSSAATAFIQPASP 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCDC6	NP_005427.2	DUF2046	52..337	CDD:401633	188/289 (65%)
CG6664	NP_648944.1	DUF2046	4..310	CDD:401633	193/317 (61%)