Protein Alignment CCDC6 and ccdc6b

DIOPT Version :10

• Sequence 1: NP_005427.2
• Gene: CCDC6 / 8030
• HGNCID: 18782
• Length: 474
• Species: Homo sapiens
• Sequence 2: NP_956535.2
• Gene: ccdc6b / 393211
• ZFINID: ZDB-GENE-040426-869
• Length: 437
• Species: Danio rerio
• Alignment Length: 461
• Identity: 395/461 - (85%)
• Similarity: 409/461 - (88%)
• Gaps: 35/461 - (7%)

Human     1 MADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLAS 65
            |||||||||||||          ...|||:|              |..|:||.||||||:|||||
Zfish     2 MADSASESDTDGA----------TPHCSSSS--------------SSSILISSFRLEELSNRLAS 42

Human    66 LQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETL 130
            ||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish    43 LQQENKVLKIELETFKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETL 107

Human   131 AVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQL 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   108 AVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQL 172

Human   196 RREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRD-ISMEIDSPENMM 259
            |||||||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Zfish   173 RREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDTISMEIDSPENMM 237

Human   260 RHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSE 324
            |||||||:|||||||.||.::|||:||.|||:||||||||||:|||||||||:||||||||||||
Zfish   238 RHIRFLKSEVERLKKNLRTSELQHTEKRAQYIEEERHMREENIRLQRKLQREVERREALCRQLSE 302

Human   325 SESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAG 389
            ||||||||||||||||||||||||||||||||:|||||||||||||||.||||||||||:|||||
Zfish   303 SESSLEMDDERYFNEMSAQGLRPRTVSSPIPYSPSPSSSRPISPGLSYVSHTVGFTPPTTLTRAG 367

Human   390 MSYYNSPGLHVQHMGTSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPP-------- 446
            ||||||||||. |:|.||||.|||||||||||||||||||||||||..|||||||||
Zfish   368 MSYYNSPGLHA-HVGASHGIARPSPRRSNSPDKFKRPTPPPSPNTQAGVQPPPPPPPIAHPVFSH 431

Human   447 -PPMQP 451
             .|.||
Zfish   432 NAPQQP 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCDC6	NP_005427.2	DUF2046	52..337	CDD:401633	271/285 (95%)
ccdc6b	NP_956535.2	DUF2046	31..315	CDD:401633	270/283 (95%)