Protein Alignment CUBN and cubn

DIOPT Version :10

• Sequence 1: NP_001072.2
• Gene: CUBN / 8029
• HGNCID: 2548
• Length: 3623
• Species: Homo sapiens
• Sequence 2: XP_021326049.2
• Gene: cubn / 100144772
• ZFINID: ZDB-GENE-060228-6
• Length: 3626
• Species: Danio rerio
• Alignment Length: 3647
• Identity: 1938/3647 - (53%)
• Similarity: 2544/3647 - (69%)
• Gaps: 46/3647 - (1%)

Human     2 MNMSLPFLWSLLTLLIFAEVNGEAGELELQRQKRSINLQQPRMATERGNLVFLTGSAQNIEFRTG 66
            |..:|.|.|..:.||.||.:.|:.|.....||||:|:.:||||.:|.|:|.|..|..::|.|.|.
Zfish     1 MAQTLSFSWIFIFLLFFAGLQGDRGGQNHSRQKRAISSEQPRMISENGHLTFSAGYNKDIRFTTS 65

Human    67 SLGKIKLNDEDLSECLHQIQKNKEDIIELKGSAIGLPQNISSQIYQLNSKLVDLERKFQGLQQTV 131
            ..|.:|:..|||...::||:||||||..:|.|  |..::|.:|::.|::::..||.|.|.::|||
Zfish    66 GTGSLKVGAEDLILQINQIKKNKEDIDTIKNS--GPSEDIKNQLHLLDTRVTTLESKVQSIEQTV 128

Human   132 DKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGS 196
            .:|.||||||||.||||||.|:|.|:||..|:||.|:.|||||::.:||||.||||.||.||.||
Zfish   129 QRKTCSSNPCQNTGTCLNLLDAFHCLCPDNWQGPTCAVDVNECQVLAGTPLGCQNGATCNNTPGS 193

Human   197 YSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMFSPNSPACT 261
            |:|.|.||.|||.|.|:||||.|||...||||:|.|..|....||||.|:|||||...|...|||
Zfish   194 YTCTCTPEWYGPHCTSRYDDCAGGSQDLCVHGLCIDSDRVNPNEPKYKCICDAGWTSPPGVAACT 258

Human   262 LDRDECSFQPGPCST--LVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVEC 324
            .|.||||....||||  .|:||||.|||||||||:|||||||.|:|::||..||||||.:|.|.|
Zfish   259 ADIDECSLPTKPCSTNPPVECFNTLGSFYCGACPSGWQGNGYSCQDVDECATNNGGCSTSPFVPC 323

Human   325 VNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGS-LPLCTCLPGYTGNGYG 388
            :||.||.||..|||||:|||:.||..||||.:||||.|.|:|:||.|| :|||||.|||.|||||
Zfish   324 LNTMGSFHCGQCPPGYEGDGKTCTQADICSTNNGGCFPLATCTSTPGSTIPLCTCPPGYVGNGYG 388

Human   389 PNGCVQLSNIC-LSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVD 452
            |.||.|:|:|| .|:||:||||.:|.:||.|.||.||.|.||.:|:|||.||||.|||||.||::
Zfish   389 PTGCTQISDICGTSNPCVNGQCENTATGYVCHCDPGWAGQNCDQNMNECSSNPCQNGGTCTDGIN 453

Human   453 SFSCECTRLWTGALCQVPQQVCGESLSGINGSFSY-RSPDVG-YVHDVNCFWVIKTEMGKVLRIT 515
            .::|.||..|||..||.|||.||..|....|:||| .:|..| |.|.|:|.|||:|:..::||||
Zfish   454 GYTCTCTAQWTGPQCQTPQQECGGILESPAGTFSYPNNPGTGDYDHQVSCAWVIRTDPNQILRIT 518

Human   516 FTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFT 580
            |.||.:|:..:|..:||||:||:|:|||.:|::|||:.|.||.||.|:|||...|:|..:..|||
Zfish   519 FPFFDIENSASCNFDFLQVHDGESASAFVIGKYCGSAAPAELFSSHNSLYFWFRSDHSVSAGGFT 583

Human   581 VRWETQQPECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNK 645
            |.|::|.|.|||.||..||.||||||||||||.|||.|.|..:|.||:||.||||||||||:||.
Zfish   584 VAWQSQAPVCGGQLTNTYGDIKSPGYPGNYPPNRDCYWTVNVNPGLLITFAFGTLSLEHHDNCNF 648

Human   646 DYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTSPSDLRCGG 710
            |:||||||.|.:|.||||:|:|.|.||||||||.|.||||||..|||:||||||.|||||..|||
Zfish   649 DFLEIRDGLLPEDSLLGKYCSTASPPPLQTTGPSAWIHFHSDFSISDRGFHITYTTSPSDPGCGG 713

Human   711 NYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIEVRDG---- 771
            .:|:.||.:..|.....:.|.|||:|:::.|:.||:.:||||::|:..:....:::|||||
Zfish   714 VFTETEGIIISPNWPNNYAHNRQCIYIIRMPRSEQVALNFTHMDLETHTGCLFDFVEVRDGTGET 778

Human   772 ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQVACGDELTGEGVIRSPFFPNVY 836
            :.|:||.|||...:.|.|.||.:||||:.|:||.:|.|||:|::|||..|:|.|.||:||.|:.|
Zfish   779 DPLIGKYCGNTLPAPILSTTNGLWIRFQSDSSVSRAGFRAMYELACGGTLSGTGQIRTPFHPDPY 843

Human   837 PGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKYCGTDIPSFITS 901
            |..:.|.|.|:||:..|:.|||..|::..|:.|..|:||:.......||...:|||.::|..:.|
Zfish   844 PHNKVCEWVINQPEGYVVTLNFLTFDVEGSSTCAFDHVEVRDGPSSSSPLIGRYCGVEMPPMLES 908

Human   902 VYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQP 966
            ....:::.|...:|..||||.|:|.:.:..|||.|||.||:..|||||..||||.||||:|.|.|
Zfish   909 TQKSMFIQFKTDASVSNHGFTAEFGSAEQGCGETLTEPTGSFTSPGHPTEYPHGANCTWYISVPP 973

Human   967 NHLIHLMFETFHLEFHYNCTNDYLEVYDTDSE---TSLGRYCGKSIPPSLTSSGNSLMLVFVTDS 1028
            .|||.|.|..|::|||.||..||::|||..:.   |.|||:||:|:||||||:.:.:.::.|:||
Zfish   974 GHLIRLSFSYFNMEFHTNCAYDYVDVYDNGTALTGTLLGRFCGRSVPPSLTSTDSLMTVLLVSDS 1038

Human  1029 DLAYEGFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNF 1093
            .|:.|||..:|.:|:|.|.|.:.:....|..:|||:|:|||.|.||:|||.|.....|.::||:|
Zfish  1039 SLSAEGFSADYISINATTDCSKVFRTSTGELSSPNYPDNYPTNRECVYRIIVEVNMQIMLNFTDF 1103

Human  1094 SLEEAIGNYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYW 1158
            .| |...:...|:|||||||||.|||:|.:.|:|.||.|:||||:||:||:||...|..||.|:|
Zfish  1104 QL-EGFSSCGFDYLEIRDGGYETSPLIGRYCGTNAPPIIVSHSNRLWMKFRSDHSLTYKGFQAHW 1167

Human  1159 DGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYL 1223
            ||:.|||||.||||||.|.|||||:||..::||||.:|:|.||..:|.|.|||||...:|..|||
Zfish  1168 DGTQTGCGGTLTTSSGGFTSPNYPLPYPANAECYWHIKTSAGSRIQLSFGDFHLEDTVDCYFDYL 1232

Human  1224 AVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYRQTCENVVIVNQTY 1288
            .||||.:||:|.|.:|||::.|..|.||.::|::|||||......||.|.|..||..::|.|::.
Zfish  1233 MVYDGNNSNAHQLAKLCGNQIPAPISSSRENMYVKLRTDSIIHTGGFLANYHSTCNGMLIANRSR 1297

Human  1289 GILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDGPRQ----MGR 1349
            |::||:.|||.|..:..|:|||:|..|||:||||:||::|....|..|:::|||||..    :|.
Zfish  1298 GMIESLNYPNDYPSHADCSWTIQAYMGNTINYTFIAFEVEQSDGCGYDHVKLYDGPNDQANLIGT 1362

Human  1350 YCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELSGATGSFSSPGFPNRYPPN 1414
            :||...||.|:|:.:.|.::..:| :....:||||.|:..||||||.|..|:|:|||:|.:||.|
Zfish  1363 FCGNVPPPAGTTSGTSLHIVFRSD-MSISYRGFQMDWYQNGCGGELFGPVGTFNSPGYPGQYPMN 1426

Human  1415 KECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQLCTQRSPENPMQVSS 1479
            :||:|:|.|.|||||.:||.:||||||..||:|.||:|||||..:||:|||||.|.|.||:||||
Zfish  1427 RECVWHIHTSPGSSISITILEFDVEYHPDCNYDKLEVYGGPDLSAPRLAQLCTTRPPSNPLQVSS 1491

Human  1480 TGNELAIRFKTDLSINGRGFNASWQAVTGGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDR 1544
            |||.:.:||.:|..::||||||:|..|.|||||...|||||||||.|||.|..|.||||||.||.
Zfish  1492 TGNAVTVRFTSDAVVSGRGFNATWIEVPGGCGGSVTAPSGEIHSPQYPSNYPDNADCSWVITVDA 1556

Human  1545 NHRVLLNFTDFDLEPQDSC----IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGP 1605
            .|||..||||.|:|.|.||    :..:||.......||:.||..: ..|:.||.|.:::||:|..
Zfish  1557 GHRVFFNFTDLDIENQFSCSYDYVAIHDGPHEHSPLLAQVCGTSR-PPPVTSSTNVIYVRFRSDH 1620

Human  1606 SRQNRGFRAQFRQACGGHILTSSF-DTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFEL 1669
            |..:|||.|||.:|||..|:|... ..::|||:|..||.||:|||||:||.|.||:|||||.|||
Zfish  1621 SLNHRGFSAQFSEACGSFIVTDDVGGEIASPRYPYPYPPNQDCSWIIRAQEPFNHVTLSFTDFEL 1685

Human  1670 ER-STTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTA 1733
            |. ::.|..|.||||||.:..||..|||||:::|||:||.|:|:.::||||.::...||..|..|
Zfish  1686 EMLNSNCTHDSVEILDGDNVQAPSVGRYCGSNLPHPVTSLSNAMVVKFVSDHAVGRKGFRATYMA 1750

Human  1734 SVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEI 1798
            |.|.|||...|..|.||||.|||:|||||||||.:.||||||:|||||.|||:.|.|||.|::||
Zfish  1751 STSGCGGLLNMESGAFNSPNYPDVYPPNVECVWTLTSSPGNRIQLSFIMFQLQPSSDCSNDYLEI 1815

Human  1799 REGNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIFGNDNIVGTHGKV 1863
            |||::||.||||:||:|.|.||:||.||.||::|.||.|.||.||:|.|..::||| |.|:.|.:
Zfish  1816 REGHSTGALVGRFCGDSLPTNYTSITGHILWIKFFSDSSISGAGFRAVFSHLYGND-ITGSTGLI 1879

Human  1864 ASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHARLIGAYCG 1928
            |||.:|..||:|::|:|||.|::...:..:.|::|||::.||.||||:||||||.::.|:|.:||
Zfish  1880 ASPLYPRTYPNNADYRWTVTVDSDSHIQIQFLDIDIEDLFNCLYDKLKIYDGPSTNSFLLGEFCG 1944

Human  1929 -TQTESFSSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTIAPGACGGFLRTGDAPVFLF 1992
             |......|:|:::|..|.||:.|.|||||:||.||.. .|.||||.||||||.|.|||.|.|||
Zfish  1945 LTLPNPVRSSGSAITLEFQSDTVIGGKGFLIEWTAVQG-SGPLPTIEPGACGGTLVTGDTPQFLF 2008

Human  1993 SPGWPDSYSNRVDCTWLIQAPDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQLAVLCGRE 2057
            |||||:.|.:.:||:|:|::|.|.||.|:||||:|...:|.:|||.||||:.|.:..:|.:|||:
Zfish  2009 SPGWPELYQHNLDCSWVIRSPSSIVEFNLLSLDMEDEVSCLHDSLDIRDGETNASPLIAKVCGRQ 2073

Human  2058 IPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYLHADRGIITSPKYPETYPSNLNCSWHV 2122
            :||.:.|||:.|.:|||||.|:...||||:|.:.|||:||.|||:::||:||:.|..||||:|.|
Zfish  2074 LPGSLHSTGDAMLLRFTSDGSINGRGFNATFSRGCGGFLHTDRGVLSSPQYPQNYKPNLNCNWQV 2138

Human  2123 LVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTS 2187
            :|..|..::|.|:.|||:....:.|:.||||.||||||..||.|     :|..|||:..||..|:
Zfish  2139 MVTPGFRVSVTFQSPFQVQGYGNQCSTGDYLELRNGPDGNSPTL-----SGRLCGSNVPSTFQTT 2198

Human  2188 DNQMFVQFISDHSNEGQGFKIKYEAKSLACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILA 2252
            ||.::..|:||.||||.|||:.:||.|.||||.:.::|.|..||:|||::|.|||.:.||:||:.
Zfish  2199 DNSLYAHFVSDGSNEGNGFKLLFEAHSSACGGFIELNDGDPPGYITSPDYPSNYPQNIDCVWIIT 2263

Human  2253 APPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFR 2317
            .|....:||.||..|.||....|..:|:|:|||..|||.::.:.||.:.||:|.|||..||||||
Zfish  2264 VPNGEAVQLDFEGDFYIEPHSGCLFDYIEIRDGPTSDADLIGRLCGNTRPSTQHSSGTTMYLRFR 2328

Human  2318 SDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDF 2382
            :|.|.||:|||||||||.|||...||:||:.|.|.|...|.||..|||:|:|.:|||||:::..|
Zfish  2329 TDASVTHIGFKAKYSIAVCGGTYIGQNGVIRSPGFPGSNYPDNSNCEWYLEGPTGHYLTLTYTAF 2393

Human  2383 NLQNSSGCEKDFVEIWDNHTSGNILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFES 2447
            :||:|:.|..|:|||.:.:.||.:||::|||.:|..:||..:.|.|:||:|.|..|.||.|.||:
Zfish  2394 DLQSSANCNSDYVEIREYNASGRLLGKHCGNNLPAPMDTGDSFAYVKFVSDASANAGGFSLSFEA 2458

Human  2448 SMEECGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIV 2512
            |:|||||||....||.:||||||..||.|||.|.||.|:|||:||..|:|||....:|..:.|.:
Zfish  2459 SIEECGGDLNAPFGTISSPNYPNLYPHSRICRWSITVPQGRRVTLTINDLRLEDQSTCAFDFVEI 2523

Human  2513 FNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCGGSLPNT 2577
            .||:..::|:|::||.:|....::|||||||.|||.||.|...|||||.|:|.|.|||||.| |.
Zfish  2524 LNGLTPSAPRLDRLCGTVPAGTQVKSSGNTMTVIFSTDSSVSNGGFTADYSSEESAVCGGIL-NE 2587

Human  2578 PEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFRVGDADG 2642
            | ||||||.: |..|||.||||||.:.||:..||||.:..::.:||.||.|::|.||||:||.:|
Zfish  2588 P-GNFTSPDF-GNGNYSNNLNCEWLIQNPHHTNSSIVVIIDELHLEHHQTCEWDYLEFRLGDHNG 2650

Human  2643 PLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYSFTDCGGIQIGDSGVITSPNYPN 2707
            .|:.||||.:.|::|:|:....:|:||:::|.|..:||.|.|.|::|||.|.||.|||:||.|||
Zfish  2651 ELLTRLCGQTPPSIPIVVSTPSLWVHFLSDEAVGDLGFKATYYFSECGGTQSGDGGVISSPGYPN 2715

Human  2708 AYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTI 2772
            .|.|.:.|:.|||||.|||:.|||:.|::|.|:.|.|||||:.||.|..|||||||||:::|.||
Zfish  2716 VYPSPSRCTWLLEAPVGHTVVLTFTYFEVEEHSQCVWDSVTIFNGASSGSPIIGQYCGHNSPGTI 2780

Human  2773 QSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFHSDNGTIRSPHWPQNFPENSRCSWTAIT 2837
            :||||:|||.|.:||::..|||.|||:|.:.|||||.|:|.|||:||::|||||.|..||||.|.
Zfish  2781 RSGSNKLVVVFLADHTVSKGGFAATWSTDSTGCGGIIHADTGTIKSPNYPQNFPTNIECSWTIIA 2845

Human  2838 HKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVF 2902
            |...|||:.|.::|.||...||||||::|:|:...:.|:.|||||||..||..:|.|.|..||.|
Zfish  2846 HDGNHLEMGFASDFQIPDSSGQCQNSYIKMWSDNIQNDENLLATGCGTTAPAAIIAPRNVITARF 2910

Human  2903 QSQEAPAQGFSASFVSRCGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHL 2967
            ||.:.|.:||||:|.:.||:|||..||.::|||||..|..|.||.|:|.|....||:|||.:|.:
Zfish  2911 QSSDTPGKGFSAAFYTTCGANFTASSGRVVSPNYPDHYPANSNCNYIINAGEQFVVVLTFRTFQI 2975

Human  2968 EARSAVTGSCVNDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVLLNFYSNEQITDFGFKFSY 3032
            ||.|    :||.|||.|..|.:..|:|.||:||:.:|...|..||:|:||||:..|.|.||...|
Zfish  2976 EAHS----TCVYDGVKIYSGTTASSSPLATLCGNTIPGIFTTFGPMLINFYSDSIIHDNGFLAEY 3036

Human  3033 RIISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLA 3097
            ..|.||||||.::|.|.||::|.::|.::::|.|.|.|.:::||.|||:.|::..|::|:.||:|
Zfish  3037 TTIPCGGVFNGTAGTIGSPSHSISNYHHNINCTYHIYVRNNRVINLKFNSFNLEASSTCNFDYVA 3101

Human  3098 IYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQTLGPQQGCGGYLT 3162
            :|||.:|..||:|||||.:.|||::||.|.|.|.|.|||...|:||:.::.:||||||||||:|:
Zfish  3102 VYDGESTLAPLMGKFCGHELPPNLRSSTNHMFLQFVTDSSVAAEGWRATYSETLGPQQGCGGFLS 3166

Human  3163 GSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYDGDS 3227
            ..:..|.|||.|.||.|:.:::|:|.|...|||.|:|||.:|.|| .||...|.||:|.:|||||
Zfish  3167 SPSGMFGSPDIDMNGQYEPHMDCMWTIAVEVNKAINLTFTSFELE-GSTGTLCRYDHVTIYDGDS 3230

Human  3228 ENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATYTIMDMPCGGTYNATWTPQNIS 3292
            .|..|.|||||..:||||||:.|||||.||||.|:.|.||||||:.::..|||.:|||.|.|.|:
Zfish  3231 ANFPLVGTFCGDLIPAPFISASNFLTVHFISDGTVSRRGFNATYSTVNSLCGGAFNATATSQTIT 3295

Human  3293 SPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQL-TSQDCTQNYLQLQDSPQGHGNSRFQFCGR 3356
            ||...:...||:.|.||:|:|..:.||::|....| |||.||.|:|:.:|.|.|......:||..
Zfish  3296 SPLYPNAYPPFTSCRWVLDAPSQEGVKVSVQQFHLDTSQSCTSNFLEFKDFPVGDYGQAHKFCSA 3360

Human  3357 NASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTYQIADCNRDYHKAFGNLRSPGWPDNYDNDKDC 3421
            : |.||.|||...|..:.|||......:..|.:||:|.|:|.|.:.:|.|:||||||.|.::.:|
Zfish  3361 D-SHVPDFYSYGRTMHITFKSEAFMTGNGFSLSYQVAGCSRVYEQEYGYLKSPGWPDLYPHNLEC 3424

Human  3422 TVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELY 3486
            ::.|.||||..|||||.|..:|....|..|:|||||||.:.||||||:||..||||||..:|||:
Zfish  3425 SIVLQAPQNSFISLFFTSFDVETHPSCNFDYLEVRNGSTATSPLLGKHCGNTLPNPVFPGSNELF 3489

Human  3487 LRFKSDSVTSDRGYEIIWTSSPSGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTI 3551
            :.||||..|:..|:||.|||||.||||.||||.||||||.|||||.|.:.|||.:.||:||:||:
Zfish  3490 IFFKSDFTTTRNGFEITWTSSPQGCGGVLYGDHGSFTSPNYPGTYANGSSCEWSIRAPSGRVVTV 3554

Human  3552 NFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSA 3616
            .|..|||||||||..|||.|:|||:|:||:.|||||.:|:||||.||||.||:||.|..|..||.
Zfish  3555 TFNQISIDDPGDCQNNYLKLFDGPDANSPAVGPYCGLETNIAPFRASSNLVFVKFSAQSAVLPSG 3619

Human  3617 FRLTWDS 3623
            |||||.|
Zfish  3620 FRLTWSS 3626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CUBN	NP_001072.2	cubilin_NTD	32..135	CDD:412063	43/102 (42%)
		Interaction with AMN. /evidence=ECO:0000269|PubMed:30523278	42..49		4/6 (67%)
		EGF_CA	136..167	CDD:238011	22/30 (73%)
		EGF_CA	170..210	CDD:238011	27/39 (69%)
		EGF_CA	263..304	CDD:214542	30/42 (71%)
		EGF_3	309..347	CDD:463759	24/37 (65%)
		EGF_3	353..387	CDD:463759	23/34 (68%)
		EGF_CA	399..430	CDD:238011	18/31 (58%)
		EGF_CA	432..468	CDD:238011	21/35 (60%)
		CUB	474..585	CDD:238001	56/112 (50%)
		CUB	590..699	CDD:238001	79/108 (73%)
		CUB	708..815	CDD:238001	47/110 (43%)
		CUB	817..927	CDD:238001	42/109 (39%)
		CUB	932..1041	CDD:238001	61/111 (55%)
		CUB	1048..1157	CDD:412131	54/108 (50%)
		CUB	1165..1275	CDD:238001	60/109 (55%)
		CUB	1282..1388	CDD:238001	45/109 (41%)
		CUB	1391..1505	CDD:238001	71/113 (63%)
		CUB	1510..1617	CDD:238001	56/110 (51%)
		CUB	1620..1733	CDD:238001	60/114 (53%)
		CUB	1738..1847	CDD:238001	72/108 (67%)
		CUB	1859..1962	CDD:238001	48/103 (47%)
		CUB	1978..2088	CDD:395345	60/109 (55%)
		CUB	2092..2212	CDD:238001	59/119 (50%)
		CUB	2217..2333	CDD:238001	59/115 (51%)
		CUB	2336..2447	CDD:238001	53/110 (48%)
		CUB	2452..2564	CDD:238001	59/111 (53%)
		CUB	2570..2686	CDD:238001	58/115 (50%)
		CUB	2689..2800	CDD:238001	68/110 (62%)
		CUB	2805..2918	CDD:238001	62/112 (55%)
		CUB	2920..3034	CDD:238001	55/113 (49%)
		CUB	3037..3148	CDD:238001	53/110 (48%)
		CUB	3157..3273	CDD:238001	66/115 (57%)
		CUB	3278..3392	CDD:238001	46/114 (40%)
		CUB	3395..3506	CDD:238001	60/110 (55%)
		CUB	3511..3621	CDD:238001	73/109 (67%)
cubn	XP_021326049.2	None