Protein Alignment MLLT10 and zfp-1

DIOPT Version :10

• Sequence 1: NP_001182555.1
• Gene: MLLT10 / 8028
• HGNCID: 16063
• Length: 1068
• Species: Homo sapiens
• Sequence 2: NP_001379957.1
• Gene: zfp-1 / 176237
• WormBaseID: WBGene00006975
• Length: 867
• Species: Caenorhabditis elegans
• Alignment Length: 27
• Identity: 9/27 - (33%)
• Similarity: 14/27 - (51%)
• Gaps: 0/27 - (0%)

Human    84 LLAVTLIVLNSTLKSFDQFTCNLLYVS 110
            |.|:..:.|....:..|..|||::.||
 Worm    62 LRALEYLGLGDQNQHIDALTCNVMKVS 88

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MLLT10	NP_001182555.1	PHD_AF10_AF17	24..71	CDD:277049
		ePHD_AF10	78..206	CDD:277178	9/27 (33%)
		Self-association	80..287		9/27 (33%)
		Required for interaction with histone H3. /evidence=ECO:0000269|PubMed:26439302	106..190		2/5 (40%)
		Interaction with FSTL3. /evidence=ECO:0000269|PubMed:17868029	141..233
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..260
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	291..505
		DNA-binding	311..674
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	583..612
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	660..708
		Transactivation domain, required for DOT1L-binding	703..784
		CC_AF10	715..778	CDD:411015
		Leucine-zipper	750..778
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	800..865
zfp-1	NP_001379957.1	PHD_AF10_AF17	7..54	CDD:277049
		ePHD_AF10_like	72..185	CDD:277142	6/17 (35%)
		CC_AF10	593..654	CDD:411015