Protein Alignment GRPEL1 and Roe1

DIOPT Version :10

• Sequence 1: NP_079472.1
• Gene: GRPEL1 / 80273
• HGNCID: 19696
• Length: 217
• Species: Homo sapiens
• Sequence 2: NP_610886.2
• Gene: Roe1 / 36508
• FlyBaseID: FBgn0014877
• Length: 213
• Species: Drosophila melanogaster
• Alignment Length: 212
• Identity: 101/212 - (47%)
• Similarity: 133/212 - (62%)
• Gaps: 7/212 - (3%)

Human     9 ARRSLPALALSLRPSPRLLCTATKQKNSGQNLEEDMGQSEQKADPPATEKT-----LLEEKVKLE 68
            |:.:|| |.:..|....|..:.|.|..|...|.....|.|:..:..|||.:     |.:|....:
  Fly     3 AKAALP-LQMFGRRLVHLRSSVTSQNMSALRLYSTEKQPEEATEQKATESSPEVEKLTKELAAAK 66

Human    69 EQLKETVEKYKRALADTENLRQRSQKLVEEAKLYGIQAFCKDLLEVADVLEKATQCVPKEEIKDD 133
            ||..|.::||||:|||:||:|.|..|.:.:||::|||:||||||||||.|..|||.|||::: ..
  Fly    67 EQNAELMDKYKRSLADSENMRNRLNKQISDAKIFGIQSFCKDLLEVADTLGHATQAVPKDKL-SG 130

Human   134 NPHLKNLYEGLVMTEVQIQKVFTKHGLLKLNPVGAKFDPYEHEALFHTPVEGKEPGTVALVSKVG 198
            |..||||||||.||...:.:||.:|||..|:|:..||||.:|||||....:..||.||..|:|:|
  Fly   131 NADLKNLYEGLTMTRASLLQVFKRHGLEPLDPINQKFDPNQHEALFQKEDKTVEPNTVVEVTKLG 195

Human   199 YKLHGRTLRPALVGVVK 215
            ||||.|.:|||||||.|
  Fly   196 YKLHERCIRPALVGVSK 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GRPEL1	NP_079472.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..56		6/26 (23%)
		GrpE	72..213	CDD:271355	79/140 (56%)
		2-helical coiled coil	72..122	CDD:271355	29/49 (59%)
		2-helical coiled coil	143..158	CDD:271355	6/14 (43%)
Roe1	NP_610886.2	GrpE	70..210	CDD:271355	79/140 (56%)
		2-helical coiled coil	70..120	CDD:271355	29/49 (59%)
		2-helical coiled coil	140..155	CDD:271355	6/14 (43%)