Protein Alignment STAM and Gga

DIOPT Version :10

• Sequence 1: NP_003464.1
• Gene: STAM / 8027
• HGNCID: 11357
• Length: 540
• Species: Homo sapiens
• Sequence 2: NP_572571.1
• Gene: Gga / 31902
• FlyBaseID: FBgn0030141
• Length: 660
• Species: Drosophila melanogaster
• Alignment Length: 591
• Identity: 104/591 - (17%)
• Similarity: 193/591 - (32%)
• Gaps: 184/591 - (31%)

Human   148 SAQQAEVFTKQIQQLQGEL------------QHLREEISLLEHEKESELKEMEQELHLAQAEIQN 200
            |.|..|:..|.:||:....            :..||.|..:|.|:...|:..::    |:..|.:
  Fly    15 SRQITELPPKALQQIFATCSATDMTRCSLVNKQFREVIEDMEDERAESLRSCQK----AKIFICD 75

Human   201 LRQA---------------------AADSATEHESDIASLQDDLCRLQNDLDDMERIRGDYEMEI 244
            .|:|                     ::||.:...|.|||.........:.....:..:...|.|.
  Fly    76 RRRAILEGVSTVTPSRLPRTPKNSESSDSGSASSSSIASTSSSEADSVSSSSKTKTKQQQTEREK 140

Human   245 ASLRAEMELKTSEPSNLSISDFSGIQDELHHLRERYNLLNEEYQALRESNSSLTGQLAE------ 303
            ...|..:..:|.  |:.|.:|.|||..      :..:.|:::|....:.|.:......|
  Fly   141 ELRRRNISDRTK--SSSSSTDSSGIHS------KATSFLSDQYTDTTDPNWAFAFHFDEWLQEYD 197

Human   304 ------------LESDR--------TRRATERWLESHLLRSTMSSESQTSELDFPEPDPVMQL-L 347
                        ||.::        :.:....:.|:.|::...::.| .::......:|..:| :
  Fly   198 VNDVFFKNFCSFLEREKIEDPMSPSSYKGRTAYYENQLIQDKTTAMS-LADCQIVRLNPTAELEM 261

Human   348 RQQLLGAEEQMQDMQDKCKNLYCELEELQHHRRTSEEEQKRLQRELKC--AQNEVLRFQTSHSTQ 410
            |.|..|..|::.|...|.:|.:.                  :.::..|  |:..|..|   :...
  Fly   262 RNQSAGRIERLADRLSKIRNAHF------------------IFKDSVCYGARPPVTFF---YFLS 305

Human   411 HEELKSRLCTLQQKYDASQDEHSELLKVQMQLETELQQLRLLRCTPVESQSEKELMCRLQKLQAQ 475
            .....:|..|......||..|..|:|.:.          .|.|.|.::.|..:.:|.|
  Fly   306 MMRRNTRALTFDNVQAASTIELHEVLNLS----------NLNRLTVIQPQQHQTIMVR------- 353

Human   476 HQCSVNEKEQLLEVQHHLHDKLR---------CHESEVHRLRSMVDCLREKNEKNSGIHLQLQEM 531
                    :|||.....|.|::|         |||.....|.::|                 ||.
  Fly   354 --------DQLLINWMKLPDQIRKRISVHLVGCHEFRPQNLYNVV-----------------QEW 393

Human   532 KGLYQ---FSRDELERQKHMYDQLEQDFLLCQQELTELKSSQSLCEEN-GNCSNKCDALLARLTE 592
            .||.:   |.:..::...:.|::. .:.:....::.|.:..:|....: ||..|:...:|.|..
  Fly   394 LGLAKPVVFKQISIDGGSYKYNEF-MNIIEHLHDIIEKRPPRSPMNRSFGNEQNEHSIVLERTC- 456

Human   593 LQDKFKASQEEIGH-------LQMEQCELLEDQRR----LQEEQGQLQ-------EELHRLTFPQ 639
                      .|.|       :|::.|   :..||    ::.|...:.       ..|.||..||
  Fly   457 ----------RIPHPKDRRVVIQLKYC---KPSRRMVLTIEREDSPIPVTTLTPVSSLSRLARPQ 508

Human   640 PKCGIL 645
            ....:|
  Fly   509 SAASVL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STAM	NP_003464.1	VHS_STAM1	9..139	CDD:340797
		SH3_STAM1	213..267	CDD:212897	11/53 (21%)
		GAT_STAM1	301..377	CDD:410594	15/102 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	500..540		9/42 (21%)
Gga	NP_572571.1	VHS_GGA_metazoan	8..144	CDD:340769	24/132 (18%)
		GAT_GGA_meta	201..283	CDD:410582	14/82 (17%)
		Alpha_adaptinC2	543..644	CDD:197886