Protein Alignment ATOSB and atos

DIOPT Version :10

• Sequence 1: NP_079458.2
• Gene: ATOSB / 80256
• HGNCID: 25666
• Length: 538
• Species: Homo sapiens
• Sequence 2: NP_001369081.1
• Gene: atos / 36243
• FlyBaseID: FBgn0033638
• Length: 1338
• Species: Drosophila melanogaster
• Alignment Length: 574
• Identity: 161/574 - (28%)
• Similarity: 222/574 - (38%)
• Gaps: 139/574 - (24%)

Human    45 PGVY-QVSIFSPPAGTSEPHRALKRQAPSTEGPRELKRGPGLGAREGLPPEEPSTVGLLGPEGPG 108
            |||. |||..:......:.:..|| ..|:|.|.:..||.............:|:       .|..
  Fly   771 PGVLDQVSCRNADLNGGQNNNLLK-ATPATSGCQVCKRQKTQHNFANGKVHQPT-------NGKQ 827

Human   109 LGLGVASQHFSHRGLCVVEQRSSVTSSWTSGAWSPPCPPSNASCNTLHTRDWASPDPG------- 166
            ...|.||.|..      .|::..|..     ..:....|:...|:........:|.||
  Fly   828 ASNGYASMHLE------AEKQPDVVQ-----ILATKLTPNIERCSLNPVERCKTPPPGVADHIVV 881

Human   167 -GQGSLGESPGPAPPGQLHTLDTDLHSLAQIGGKSPVAGVGNGGSLWPRESPGTANGHSPEHTPP 230
             .:..|.:.|....|..:..|..  ..|.:...|.....:..|.:|...|:|
  Fly   882 QFKTPLSQVPAKHQPDAMVPLQQ--QQLGKSSSKPAQLRLNCGSNLLESETP------------- 931

Human   231 GPGPPGPCPTKRRLLPAGE---------------------------------APDVSSEEEGPAP 262
               ||...|..|:.||...                                 |||||..   |..
  Fly   932 ---PPMTSPQMRKALPKVNLTTIFCSSAPIAIGCPAFSFDPAALSHARSQLLAPDVSVT---PPV 990

Human   263 RRRRGSLGHPTAANSSDAKATP-FWSHLLPGPK---EPVLDPTDCGPMGRRLKGARRLKLSPLRS 323
            ::   |...||..:::....:| |....|...|   ..:.|.:|...:|    ...:|....|.|
  Fly   991 QK---SFSAPTLPHAASLSVSPRFSKQALAAHKRRSRHLSDRSDRSSLG----SDEQLSDEDLES 1048

Human   324 LRKGPGLLSPPSASPVPTPA------VSRTLLGNFEESLLRGRFAPSGHIEGFTAEIGASGSYCP 382
                 ||.||...||:...|      ..|.||||.|||||:.|..|...:.|||.::||||.:||
  Fly  1049 -----GLCSPAGGSPLKCRARLAAQFGGRPLLGNLEESLLQRRLMPKIEVMGFTLQLGASGGFCP 1108

Human   383 QHVTLPVTVTFFDVSEQNAPAPFLGIVDLNPLGRKGYSVPKVGTVQVTLFNPNQTVVKMFLVTFD 447
            ..|.:|....|:::..:....|:|..:   .|.|||||||:.||||.||.||..|||:||::.:|
  Fly  1109 TQVNIPAVSYFYELHGETLSTPYLCEI---RLPRKGYSVPRSGTVQATLLNPIGTVVRMFVIPYD 1170

Human   448 FSDMPAAHMTFLRHRLFLVPVG---EEGNANP--------THRL-----------LCYLLHLRFR 490
            ..|||..|.||:|.|:....:.   :||:..|        |.:|           |.|.:||:|:
  Fly  1171 MRDMPPLHRTFIRQRILAEELSQDQDEGHKVPRSPTVTSTTSKLGHFISAEQMKRLRYSIHLKFQ 1235

Human   491 SSRSGRLSLHGDIRLLFSRRSLELDTG---------LPYELQAVTEAPHNPRYS 535
            :||||||.||.|||||.|||: :.||.         .|.||...|..|..||||
  Fly  1236 TSRSGRLCLHTDIRLLISRRT-DCDTAAAHAKGVLEAPNELVTDTMMPAEPRYS 1288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATOSB	NP_079458.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..114		16/69 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..300		34/211 (16%)
		Required for macropage invasion. /evidence=ECO:0000250|UniProtKB:Q8BR27	348..430		37/81 (46%)
		DUF4210	348..405	CDD:404751	23/56 (41%)
		Transactivation domain 1 (TAD1). /evidence=ECO:0000250|UniProtKB:Q8BR27	436..444		5/7 (71%)
		Chromosome_seg	480..537	CDD:464021	33/76 (43%)
atos	NP_001369081.1	DUF4210	1074..1131	CDD:404751	23/56 (41%)
		Chromosome_seg	1226..1290	CDD:464021	32/64 (50%)