Protein Alignment ORAI2 and orai2

DIOPT Version :10

• Sequence 1: NP_116220.1
• Gene: ORAI2 / 80228
• HGNCID: 21667
• Length: 254
• Species: Homo sapiens
• Sequence 2: XP_005165627.1
• Gene: orai2 / 555612
• ZFINID: ZDB-GENE-060531-127
• Length: 281
• Species: Danio rerio
• Alignment Length: 275
• Identity: 217/275 - (78%)
• Similarity: 226/275 - (82%)
• Gaps: 29/275 - (10%)

Human     1 MSAELNVPIDPSAPACPEPGHK-------GMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRA 58
            ||:||.||:     ..|.||..       ||||||||||||||||||||||||||||||||||||
Zfish    15 MSSELTVPM-----GSPAPGGSDRLQDGGGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRA 74

Human    59 KLKASSRTSALLSGFAMVAMVEVQLETQYQYPRPLLIAFSACTTVLVAVHLFALLISTCILPNVE 123
            ||||||||||||||||||||||||||.||.|||.||||||.||||||||||||||||||||||||
Zfish    75 KLKASSRTSALLSGFAMVAMVEVQLEMQYNYPRVLLIAFSVCTTVLVAVHLFALLISTCILPNVE 139

Human   124 AVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDARRQ------- 181
            ||||||||||:|||||||||.||||||||||.||||||||||||||||||||||:..|
Zfish   140 AVSNIHNLNSVSESPHERMHHYIELAWGFSTALGILLFLAEVVLLCWIKFLPVDSGAQSASALVA 204

Human   182 -------PGPPPGPGSHTGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHK 239
                   |...||   |:||||||.|||||||||||||||||||||||||||||||::|||||||
Zfish   205 LKQNCSTPAVQPG---HSGWQAALASTIIMVPVGLIFVVFTIHFYRSLVRHKTERHHQEIEELHK 266

Human   240 LKVQLDGHERSLQVL 254
            :|||||||||.||.:
Zfish   267 IKVQLDGHERGLQAV 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ORAI2	NP_116220.1	Orai-1	47..228	CDD:462291	162/194 (84%)
orai2	XP_005165627.1	Orai-1	63..255	CDD:462291	162/194 (84%)