Protein Alignment ORAI2 and orai1

DIOPT Version :10

• Sequence 1: NP_116220.1
• Gene: ORAI2 / 80228
• HGNCID: 21667
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_001096448.1
• Gene: orai1 / 100125061
• XenbaseID: XB-GENE-962826
• Length: 257
• Species: Xenopus tropicalis
• Alignment Length: 257
• Identity: 210/257 - (81%)
• Similarity: 233/257 - (90%)
• Gaps: 3/257 - (1%)

Human     1 MSAELNVPIDPSAPACPEPGHKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSR 65
            ||:|||:|:|||.||..|.|:||||||||||||||||||||||||||||||||||||||||||||
 Frog     1 MSSELNIPVDPSTPAVSERGNKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSR 65

Human    66 TSALLSGFAMVAMVEVQLETQYQYPRPLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHN 130
            |||||||||||||||||||.:|.||:.||||||||||||||||||||||||||||||||||||||
 Frog    66 TSALLSGFAMVAMVEVQLEMKYGYPQLLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHN 130

Human   131 LNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDA---RRQPGPPPGPGSHT 192
            |||::||||:||||||||||||||.||||||||||||||||||||:|:   |.:......|..:.
 Frog   131 LNSVNESPHDRMHPYIELAWGFSTALGILLFLAEVVLLCWIKFLPIDSASTRNETTATQKPRGNA 195

Human   193 GWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKLKVQLDGHERSLQVL 254
            ||.:||:|||||||||:|||:|||||||:|||||||||::|||||||||||||||:|.:.|:
 Frog   196 GWNSALISTIIMVPVGIIFVIFTIHFYRTLVRHKTERHHQEIEELHKLKVQLDGHDRGINVV 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ORAI2	NP_116220.1	Orai-1	47..228	CDD:462291	151/183 (83%)
orai1	NP_001096448.1	Orai-1	47..231	CDD:462291	151/183 (83%)