Protein Alignment ABHD18 and CG32112

DIOPT Version :10

• Sequence 1: NP_001345383.1
• Gene: ABHD18 / 80167
• HGNCID: 26111
• Length: 479
• Species: Homo sapiens
• Sequence 2: NP_729820.2
• Gene: CG32112 / 317860
• FlyBaseID: FBgn0052112
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 234/513 - (45%)
• Similarity: 321/513 - (62%)
• Gaps: 66/513 - (12%)

Human     4 SKLDILYRRLLLTKLFIRGWGRPEDLKRLFEFRKMIGNRERCQNLVSSDYPVHIDKIEEQSDCKI 68
            ||||.:|||:|:|:.|.:|||:||:|:::|:|||:|.:||.|..||..||||.|.|.|..::..:
  Fly     3 SKLDSIYRRMLITRFFEKGWGKPENLRKVFQFRKVISSRESCFKLVPRDYPVEITKKEIGAESTL 67

Human    69 LDGHFVSPMAHYVPDIMPIESVIARIIDEMLDTNLILLPLFQFIVPKEW-NSKYRPVCIHLAGTG 132
            ::|.|.:||..::|.::|.||..|.               ||.::|.:| |.|::|:||||||||
  Fly    68 IEGQFKTPMELHMPGVVPEESQQAH---------------FQLLIPNKWKNEKHKPICIHLAGTG 117

Human   133 DHHYWRRRTLMARPMIKEARMASLLLENPYYGCRKPKDQVRSSLKNVSDLFVMGGALVLESAALL 197
            ||.:||||..:|:|::|:|.:.|::||||:||.|||.:|.||:|.||||:|||||.|:||...|.
  Fly   118 DHFFWRRRNFIAKPLLKDANIGSIILENPFYGLRKPNNQTRSNLHNVSDIFVMGGCLILECLVLF 182

Human   198 HWLEREGYGPLGMTGISMGGHMASLAVSNWPKPMPLIPCLSWSTASGVFTTGVLSKSINWRELEK 262
            ||.||.|:||||:||:||||||||||.:|||||:.|:|||||||||.||||||:|:||||..||.
  Fly   183 HWCERNGFGPLGVTGLSMGGHMASLAATNWPKPLVLVPCLSWSTASAVFTTGVMSQSINWDMLET 247

Human   263 QYYTQTVYEEEIIHMLEYCGTDSFKMGQEFVKHFTSSADKLTNLNLVSRTLNLDISNQVVSQKPA 327
            ||::...|.|.:..|:... .|:|..||.|:::|..|..:|..          |||:   ::|..
  Fly   248 QYFSDGQYRERLSKMVTVI-DDAFSAGQSFIQNFNQSLQELKE----------DISD---TRKIH 298

Human   328 DCHNSSKTSVSATSEGLLLQDTS-----------KMKRFNQTL---------------STNK-SG 365
            ...||:.......::|:..|:.|           |:...|.|:               .|:| ||
  Fly   299 ATENSNTCGDKYETQGICPQEDSSIFLSKSLKNTKLDSENLTIDAKDALSQKVAIETEETSKDSG 363

Human   366 YTSRNPQSYHLLSKEQSR---------NSLRKESLIFMKGVMDECTHVANFSVPVDPSLIIVVQA 421
            .|..|...:.|....||:         |...:|:|.||:|:||||||:.|||||.|.||||.|.|
  Fly   364 STLTNLMKFILPLSAQSKTDKIDITKTNWWEREALQFMRGMMDECTHLKNFSVPFDTSLIIAVCA 428

Human   422 KEDAYIPRTGVRSLQEIWPGCEIRYLEGGHISAYLFKQGLFRQAIYDAFDRFLHKYAN 479
            |:|||:||.|..||:|||||.|:|||:.||:|||:..|.|||..|.:||:|....|.|
  Fly   429 KDDAYVPREGCSSLEEIWPGAEVRYLDAGHVSAYVLHQKLFRSCIIEAFERAKKIYEN 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABHD18	NP_001345383.1	ABHD18	16..472	CDD:370661	223/492 (45%)
CG32112	NP_729820.2	ABHD18	15..479	CDD:370661	223/492 (45%)