Protein Alignment THOC7 and thoc7

DIOPT Version :10

• Sequence 1: NP_079351.2
• Gene: THOC7 / 80145
• HGNCID: 29874
• Length: 204
• Species: Homo sapiens
• Sequence 2: NP_728489.2
• Gene: thoc7 / 38033
• FlyBaseID: FBgn0035110
• Length: 288
• Species: Drosophila melanogaster
• Alignment Length: 199
• Identity: 77/199 - (38%)
• Similarity: 121/199 - (60%)
• Gaps: 1/199 - (0%)

Human     4 VTDDEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTL 68
            :.|:|:|::||||||||.|:||||.:|:|.|:||. |.|.:.....|.|:::..:||:.:..|.:
  Fly    21 MNDEEIIKQRLLIDGDGTGEDRRIVVLLKQFLKWA-SDSLDSNPIMYDRLMAQFAQCKLTALKNV 84

Human    69 LVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRH 133
            ....|...|.:||.::.:..|.||..|..:|...||:::.||:||||:.|||.||.:||..|||.
  Fly    85 QTLQMIAGERDNYTQLVEHHEESIVLAKAEIESSKKELITAKQIRKNKMEYDLLASLIQDQPDRS 149

Human   134 ETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQEASM 198
            ||.:.:|.:.:|::.|...|..:|.|.:.||..|.:|:.|||||:|.|:.|...|....:.:...
  Fly   150 ETQRHIETIRREIDDLVQKKLKMERKFQKRRNDFTLLMYTIHELEQQLDQDSSSSASSSSSDCDA 214

Human   199 ETDP 202
            .::|
  Fly   215 RSEP 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
THOC7	NP_079351.2	THOC7	7..139	CDD:461692	56/131 (43%)
		Interaction with THOC5. /evidence=ECO:0000269|PubMed:19059247	50..137		34/86 (40%)
		Interaction with NIF3L1. /evidence=ECO:0000269|PubMed:12951069	105..204		38/98 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	182..204		3/21 (14%)
thoc7	NP_728489.2	THOC7	24..155	CDD:461692	56/131 (43%)