Protein Alignment PTGES2 and Su(P)

DIOPT Version :10

• Sequence 1: NP_079348.1
• Gene: PTGES2 / 80142
• HGNCID: 17822
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_524116.2
• Gene: Su(P) / 39856
• FlyBaseID: FBgn0004465
• Length: 417
• Species: Drosophila melanogaster
• Alignment Length: 402
• Identity: 146/402 - (36%)
• Similarity: 211/402 - (52%)
• Gaps: 68/402 - (16%)

Human    23 GGRPQPLLPTQSRAGFAGAAGGP-------SPVAA-ARK--------GSPR----------LLGA 61
            |.||.|          |.:.||.       :|.|| ||:        |..|          :|||
  Fly    14 GVRPPP----------AASGGGALRLLTKRNPDAAFARRQFAVAVENGGGRKKPNGTFKLAVLGA 68

Human    62 AALALGGALGLYHT--ARW--------HLRAQDLHAERSAAQLSLSSR---------LQLTLYQY 107
               .:|.|.|..:|  .||        |...:....:...|.:.::.|         |.:.|:|:
  Fly    69 ---TVGAATGSVYTMYQRWTDGSSHKEHEETKPTRLDGIPAGVRITKRYVNPKDTSGLDIVLFQF 130

Human   108 KTCPFCSKVRAFLDFHALPYQVVEVNPVRRAEIKFSSYRKVP-ILVAQEGESSQQLNDSSVIISA 171
            :|||||.|||||||:..:.|.||||:.|.|.:|::||.:||| :|:.|:.....|:.|||.|||.
  Fly   131 QTCPFCCKVRAFLDYMGISYAVVEVDAVLRQDIRWSSVKKVPMVLIRQQDGKYVQMVDSSAIISL 195

Human   172 LKTYLVSGQ-PLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQVYGGKEARTEEMKWR 235
            :.|:|...: .:.|:..:||.....::.||:..:..|||:||..|...:.|  .||....:.|||
  Fly   196 IATHLQDKRTDIGELAQFYPHTSFFDDDGKKKNDILNKYFLMYREHTPKGV--SKETDETDRKWR 258

Human   236 QWADDWLVHLISPNVYRTPTEALASFDYIVREGK----FGAVEGAVAKYMGAAAMYLISKRLKSR 296
            .|||..||||||||.|:|..|:|.:|::..:.|:    |...|..:..|.||.||:.|:|.||.|
  Fly   259 SWADSHLVHLISPNCYQTMGESLETFEWFSQAGEWDVHFPKWERDLMVYCGATAMWAIAKMLKRR 323

Human   297 HRLQDNVREDLYEAADKWVAAVGK-DRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQ 360
            |.|.|:||..:|:|.|:|...:.| :..||||::|:||||:|:|||..|||...|.|.:|:|.|.
  Fly   324 HALSDDVRSHMYDALDQWTTELKKRNTKFMGGKQPSLADLSVFGVLSSMEGCQTFKDCLQNTSIG 388

Human   361 PWYLRVERAITE 372
            .|:..| :|:.|
  Fly   389 KWFYDV-KALVE 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTGES2	NP_079348.1	GST_N_mPGES2	101..177	CDD:239338	37/76 (49%)
		GST_C_mPGES2	224..370	CDD:198306	67/150 (45%)
Su(P)	NP_524116.2	GST_N_mPGES2	124..201	CDD:239338	37/76 (49%)
		GST_C_mPGES2	247..400	CDD:198306	69/154 (45%)