Protein Alignment ZNF703 and noc

DIOPT Version :10

• Sequence 1: NP_079345.1
• Gene: ZNF703 / 80139
• HGNCID: 25883
• Length: 590
• Species: Homo sapiens
• Sequence 2: NP_476917.1
• Gene: noc / 34847
• FlyBaseID: FBgn0005771
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 608
• Identity: 189/608 - (31%)
• Similarity: 231/608 - (37%)
• Gaps: 178/608 - (29%)

Human    64 LHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIG-----------------KPDPPPSSKLN 111
            |.|:||.||      |..:||||||||||||||||||                 ||....||..:
  Fly    19 LQPDYLAPL------PTTMDAKKSPLALLAQTCSQIGADSSAVKPLLAMDKNKTKPGACSSSSNS 77

Human   112 S-------VAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK---GSGGGDS 166
            |       ::||.:..|..|.|..|.| .:|.|.:......|..|.|.:||||..   .....:|
  Fly    78 SSSSGSAEISAAKSPSGQAKSPKSSTP-ISSTATSASLSNTSTGEIKLAFKPYETNVLSHQNQNS 141

Human   167 RKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAA---CPPFPPHGAPVSASSSSS-----SPGGS-- 221
            .|.|.|.....|..||.:|  ..|..||||.:   ..|.....|.:||..|||     ||.||
  Fly   142 FKSSSSLDAEPTRPSSKNS--SSAQERVPSRSKSNATPTDGGKAEISAHDSSSSRKTVSPSGSSQ 204

Human   222 RGGSP----HHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSE 282
            ||.||    ......|..|..        |.||.....||.:       .|...|...|......
  Fly   205 RGASPIVRSGMEVLNNANGTA--------QHPKEMSSMAAAA-------AAAAAAYKAAGPYGLN 254

Human   283 PPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGY---HGSI--VGAYAGYPSQFVPGLDPSKSGLV 342
            |.|||     ..|....:..:..| .||.:.|:   |.::  |.|..|||
  Fly   255 PLSAL-----CCPPGMEQHANPAF-RPPFAGGFSHHHAAMLAVAANGGYP--------------- 298

Human   343 GGQLSGGLGLPPGKPPS-------SSPLTGASPPSFLQGLCRDPYCLG---GYHGASHLGG---- 393
            ||...||   |.|:|..       .:|..|.:    :..:|:||||.|   ..|....|.|
  Fly   299 GGAPGGG---PAGQPNPYISYQRIKTPAGGEA----IVPVCKDPYCQGCPYSAHTQQMLMGAPCP 356

Human   394 SSCSTCSAHDPAGPSL-KAGGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHS 457
            :.|:.|. |...|.:: .|.|.|   |.||...||.:::|..||.              ...|:.
  Fly   357 AGCTQCE-HQKYGLAMASAAGLP---PAHPYSQAAAAAAANAAAA--------------RSAPYV 403

Human   458 CNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLH--- 519
            |:||.....|.|||.||:||.|||||||               ..|...||||||.|.....
  Fly   404 CSWVVGDAYCGKRFQTSDELFSHLRTHT---------------GNLSDPAAAAAALAQSQAQSLL 453

Human   520 ---LPP-------PAAPGSPGSLSLRNPHTLGLSRYHPY----------GKSHLSTAGGL---AV 561
               .||       |..|.||.|.:      ...:|||||          |.|....||..   |.
  Fly   454 GTLFPPSALRAGYPTPPLSPMSAA------AAAARYHPYAKPPPGALAGGPSPFGAAGAFNPAAA 512

Human   562 PSLPTAGPYYSPYALYGQRLASA 584
            .:....||||||||:||||:.:|
  Fly   513 AAAAALGPYYSPYAMYGQRMGAA 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF703	NP_079345.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		SP1-4_N	67..>102	CDD:425404	23/51 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	96..293		68/237 (29%)
		nlz1	311..>338	CDD:403564	7/31 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..366		8/31 (26%)
		C2H2 Zn finger	458..484	CDD:275368	15/25 (60%)
noc	NP_476917.1	zf-C2H2	402..430	CDD:395048	15/27 (56%)
		C2H2 Zn finger	404..430	CDD:275368	15/25 (60%)