Protein Alignment ZNF703 and elB

DIOPT Version :10

• Sequence 1: NP_079345.1
• Gene: ZNF703 / 80139
• HGNCID: 25883
• Length: 590
• Species: Homo sapiens
• Sequence 2: NP_523566.4
• Gene: elB / 34844
• FlyBaseID: FBgn0004858
• Length: 553
• Species: Drosophila melanogaster
• Alignment Length: 634
• Identity: 162/634 - (25%)
• Similarity: 225/634 - (35%)
• Gaps: 187/634 - (29%)

Human    55 MLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANG 119
            ||.:...|.|.|:|: ..::.|.:  :||.|.|||||||||||.||.....|.....::..:...
  Fly     1 MLQSSNHHYLRPDYM-TAAAAPTA--QLDNKSSPLALLAQTCSAIGADTTNPKLLAANIEKSTKQ 62

Human   120 LGAEKDPGRSAPGAASAAAALKQLG--DSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSS 182
            |  :..|..|:....|.:..|.|..  |..|.||||  |.|           |.|||||:.|...
  Fly    63 L--QHHPKGSSGSGGSGSFGLSQQASMDGSARDKSS--PVS-----------SHSSSVSTGSVEQ 112

Human   183 SSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHH--------SDC-------- 231
            ...|                |.||   |:|||..:|...:...|::        :||
  Fly   113 QQLP----------------PAHG---SSSSSKPTPTTFKPYEPNNNISNITTAADCGATNLSSN 158

Human   232 --------------KNGGGVGGGELDKKDQEPKPSPEPAAVSR--------GG----GGEPG--- 267
                          .||||...........:.:.||..|...|        ||    .|.||
  Fly   159 NTSAQQRVKTPKSMTNGGGQRCDSNQSASSQHRESPTAAGSLRRTPTSGLAGGVMQHNGSPGLPP 223

Human   268 ----AHGGAESGASGRKSEPPSALVGAGHVAPV-----------SPYKPGHSVFPLPPSSIGYHG 317
                ..|.:.|..|.....|.:|...|...|.:           :..|..:.|..|..:|.....
  Fly   224 TASTTPGRSNSKESAAMHSPSAAAAAAAAAAQIASSNRLQEAALAAAKEANYVKALHAASQQGSA 288

Human   318 SIVGAYAGYPSQFVPG---------------LDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGAS 367
            |...|.|.|   :.||               :.|..:......::..|.....|..:...:..|:
  Fly   289 SAAAAAASY---YPPGYGSPYSMDLMTASSLMSPHHAMFKASAMNPYLNYARMKGLTEQSMMAAT 350

Human   368 PPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDP--------AGPSLKAGGYPLVYPGHPLQ 424
            |     .:||||||.|......::..::...|.|..|        .|.|.|:.|         .|
  Fly   351 P-----NVCRDPYCTGCPASPHYINKAAGQPCPAGCPQCEGGGGGGGGSSKSSG---------SQ 401

Human   425 PAALSSSAAQAALPGHPLYTYGFML----QNEPLPHSCNWVAASGP-CDKRFATSEELLSHLRTH 484
            ..:..||:|.||.......:|...|    ....:|:.|:|:.:... |.|||.||::|..|||||
  Fly   402 GGSGGSSSAAAAAAAAAASSYHAQLAALAAASQMPYVCSWIGSDAAYCGKRFGTSDDLFQHLRTH 466

Human   485 TALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPP---------PAAPGSPGSLSLRNPHTL 540
            ||               .:..|..:||||..    :||         |..|.||          |
  Fly   467 TA---------------SVPDAVLSAAAAGG----IPPNHPLFQRTYPTPPLSP----------L 502

Human   541 GLSRYHPYGK-----SHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASA 584
            ..:|||||||     ..|:..|...:|..|....|::||:|||.|:.|:
  Fly   503 SAARYHPYGKPSMLPPSLAPPGMPGLPPHPALAQYFAPYSLYGPRMGSS 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF703	NP_079345.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		SP1-4_N	67..>102	CDD:425404	18/34 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	96..293		57/247 (23%)
		nlz1	311..>338	CDD:403564	8/41 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..366		2/24 (8%)
		C2H2 Zn finger	458..484	CDD:275368	12/26 (46%)
elB	NP_523566.4	PRK13914	<111..>188	CDD:237555	16/95 (17%)
		zf-C2H2	437..466	CDD:395048	12/28 (43%)
		C2H2 Zn finger	439..466	CDD:275368	12/26 (46%)