Protein Alignment BICC1 and YLL032C

DIOPT Version :10

• Sequence 1: XP_011538487.1
• Gene: BICC1 / 80114
• HGNCID: 19351
• Length: 998
• Species: Homo sapiens
• Sequence 2: NP_013068.1
• Gene: YLL032C / 850627
• SGDID: S000003955
• Length: 825
• Species: Saccharomyces cerevisiae
• Alignment Length: 528
• Identity: 105/528 - (19%)
• Similarity: 178/528 - (33%)
• Gaps: 167/528 - (31%)

Human   528 NTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKKISA 592
            :|...|.|..:|||.        .||.|..         |...|.|      :..:|   |:||
Yeast     8 STVITTAFLQVPHLY--------TTNRLWK---------PIEAPFL------VEFLQ---KRIS- 45

Human   593 ALNGHAQSPDIKYGAISTSSLGEKVLSANHGDPS-IQTSGS----EQTSPKSSPTEGCNDAFVEV 652
                   |.::|    :|.::       .|.||| :..:.|    :..|.|::..:...||...:
Yeast    46 -------SKELK----NTKAI-------CHIDPSWVNLNASFIRDDMISIKATTDDMDLDAICRI 92

Human   653 GMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATESPLADK 717
            .:|...:.:....:|::|         ||..::|   ::..:|          ||..|:.|
Yeast    93 SLPLPMNTNDLTAELEKM---------KRILLDL---SEKFNL----------ELIITKEP---- 131

Human   718 KAPGSERAAERAAAAQQNSERAHLAPRSSYVNMQAFDYE----QKKLLATKAMLKK-----PVVT 773
                      .....:|..|...|.   .||:...|...    :.:|||...::||     |...
Yeast   132 ----------AYFTPEQTGESKELC---IYVHALGFRSNLMECEPQLLAFVDLIKKNGMTLPPQH 183

Human   774 EVRTP--TNTWSGLGFSKSMPAETIKELRRANHVS-YKPTMTTT-----------YEGSSMSLS- 823
            .:..|  .|::|.|.....:..|..|.:.||...| |.|::.|.           :.|:..|||
Yeast   184 YIIEPMELNSYSVLPLYMGVDMENFKHISRAFKTSIYAPSLITLSRDLKANPQIFFSGAVHSLSL 248

Human   824 --RSNSREHLGGGSESDNWRDRNGIGPG-----------SHSEFAASIGSPKRKQNKSTEHYLSS 875
              |...||.:...|:|..:|....|.||           ..::......|..|..|:..|....|
Yeast   249 LARKTLRESISVNSKSFFYRRLTNITPGKLLFIRKYYQQKVNQLILKYQSLIRVTNEYIEFQSIS 313

Human   876 SNYMDCI--------------SSLTGSNGCNLNSSFKGSDLPELF--SKLG-LGKYTDVFQQQEI 923
            :|.::.:              ..::.:..|.::        |||.  |..| .|....|...:|.
Yeast   314 TNLLEMVIKNFTIQVLHEIVEVQISLNENCAMS--------PELIIDSFFGHTGNQIVVITPKED 370

Human   924 DLQTFLTLTDQDLKELGITTFGARRKMLLAISE--------LNKNRRK---LFESPNARTSFLEG 977
            .....:.:.:|...:....|     .:|..:|:        :|.|.|:   :||.......|:.|
Yeast   371 SFNQLIVVGNQSSTDEASDT-----SILHYLSDFIMGSNQVINPNLRQIKAIFEIHPDFEDFISG 430

Human   978 GASGRLPR 985
            ..:|:|.|
Yeast   431 KKNGKLTR 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BICC1	XP_011538487.1	KH-I_BICC1_rpt1	46..150	CDD:411848
		KH-I_BICC1_rpt2	155..224	CDD:411849
		KH-I_BICC1_rpt3	308..373	CDD:411850
		SAM_BICC1	896..960	CDD:188919	13/74 (18%)
YLL032C	NP_013068.1	COG5166	2..704	CDD:227495	105/528 (20%)