Protein Alignment SLC8B1 and CG34162

DIOPT Version :10

• Sequence 1: NP_079235.2
• Gene: SLC8B1 / 80024
• HGNCID: 26175
• Length: 584
• Species: Homo sapiens
• Sequence 2: NP_001097149.2
• Gene: CG34162 / 5740392
• FlyBaseID: FBgn0085191
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 613
• Identity: 131/613 - (21%)
• Similarity: 229/613 - (37%)
• Gaps: 165/613 - (26%)

Human    43 SGVNQTPVVDCRKVCGL------NVSDRCDFIRTNPDCHSDGGYLDYLEGIFCHFPPSLLPLAVT 101
            |.||:         |.|      |.:..|...|:...|.|....::||:..||.|.   ||   |
  Fly     7 SAVNR---------CSLPRESFRNANQTCGLARSTLSCGSLVYLINYLDICFCVFK---LP---T 56

Human   102 LYVSWLLYLFL------ILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIF----S 156
            :.:..|:..||      :|.:....||.|||:.:.....::  :.|.:||.||   |..|    :
  Fly    57 MSIYGLISAFLLMVHLSVLFMVTKYFFVPNLATLIEFAPMT--MFGSSFLLFG---PTFFVSYYN 116

Human   157 ALVAFSDPH-TAGLALGALFGA---GVLVTTVVAG------------GITILH--PFMAASRPFF 203
            :.....:|. ...:.|..|..|   |.::..:|.|            |||...  .|:.....:.
  Fly   117 SFWEICNPRKPESICLSPLQFAKIMGDILRYIVIGFMVICAQGYRVDGITFWSCLSFILTGMVYL 181

Human   204 RDIV--FYMVAVFLTFLMLFRGRVTLAWALGYLGLYVFYVVTVILCTWIYQRQRRGSLFCPMPVT 266
            ..::  .|.|.:.:..|...:.|||:.       ||.|.:|.:::....|...:|
  Fly   182 YIVIKKSYNVYLIVADLYSIKFRVTVF-------LYTFLMVLLVIFVVSYANFQR---------- 229

Human   267 PEILSDSEEDRVSSNTNSYDYGDEYRPLFFYQETTAQILVRALNPLDYMKWRRKSAYWKAL---- 327
                |..:..:...|....|.|||.  |..||:              .|::.|:..:.||:
  Fly   230 ----SKVKSKQTQENFLEMDSGDEI--LGKYQK--------------QMEFSRREIWLKAVNGYR 274

Human   328 ---------KVFKLPVEFLLLLTVPVVDPDKDDQNWKRPLNCLHLVISPLVVVLTLQSGTYGVYE 383
                     ::..:|..|:|...:||:..|:....|.:..:||.|...|::.:      .:|...
  Fly   275 NMADSNVIYRIAMIPSYFVLANFIPVISNDRALIGWNKYTSCLGLFFLPIICL------PHGFKA 333

Human   384 IGGLVPVWVVVVIAGTALASVTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNIL-RSL 447
            :.     |:::.:....|:.:||.:|...:.|...|:||.||.:.|:::||..:.|:.||: :.:
  Fly   334 VS-----WLIMFLTCWTLSILTFISTHSLRRPNNIWIFALLGLIVSSVFINLLSREIENIIYQYI 393

Human   448 GVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLG------ 506
            .:.|.:...|..|...    .:|:..|:..:.|....|..:.|.||.::..:...:.|.
  Fly   394 SMQFDVMPDVTALVYF----GLGEMLSESIVVRCLQQRKMWDATFGVVMSLVTYAIFLAFPLLFF 454

Human   507 -------CLLQISRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCL-LLF 563
                   |.:.:: |.||..:.                .:|.::|..|....||. |.|.: |||
  Fly   455 QGCYNNKCSIMVT-SSTETTIH----------------FIFLVLSTCLLHVSLSG-YEFRISLLF 501

Human   564 YLNFLVVALLT-----------EFGVIH 580
            ||..|.|..:|           .|..:|
  Fly   502 YLLVLTVFYVTLQWMTHYDWILSFATLH 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC8B1	NP_079235.2	PLN03151	63..584	CDD:215604	125/587 (21%)
CG34162	NP_001097149.2	None