Protein Alignment SLC8B1 and CG12376

DIOPT Version :10

• Sequence 1: NP_079235.2
• Gene: SLC8B1 / 80024
• HGNCID: 26175
• Length: 584
• Species: Homo sapiens
• Sequence 2: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Alignment Length: 644
• Identity: 145/644 - (22%)
• Similarity: 262/644 - (40%)
• Gaps: 144/644 - (22%)

Human    34 AHISPQFPASGVNQTPVVDCRKVCGLNVSDRCDFIRTNPDCHSDGGYLDYLEGIFC------HFP 92
            :::...|.|...|....|.|.........:||.|:.:..||:.....|.|:..:.|      .|.
  Fly     6 SYVPNAFDAEFDNFWDTVSCYAANTFPFEERCAFVASAKDCNRSTNVLPYMRIMACDLNCVNEFE 70

Human    93 PSLLPLAVTLYVSWLLYLFLILGV-TAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFS 156
            ..:.   :.|::. |.|..|:|.: ...|::.|.|.|:|..|.::.:|||||.|||||.:.|:||
  Fly    71 QVIF---LALFMG-LCYEILVLLIHVCNKYYSPALKAVSRFLCMNEHVAGVTLLAFGNSSADLFS 131

Human   157 ALVAFSDPHTAGLALGALFGAGVLVTTVVAGG-ITILHPFMAASRPFFRDIVFYMVAVFL----- 215
            .|.:.:    |.:.:.|...|..|..::|:|| |....||...:....|||:|.:....|
  Fly   132 NLASVN----ANVPVFANSLAAALFVSMVSGGLICYTSPFKMNAYESVRDILFLIFGSMLLQYFL 192

Human   216 ---------TFLMLFRGRVTLAWALGYLGLYVFYVVTVILCTWIYQRQRR-----------GSLF 260
                     :|:::|.             :|:||::..::..::.:|..:           |.:
  Fly   193 ASSAHVPETSFIVMFL-------------VYIFYILVNVVDVYLIRRALKTTNAQIDALLVGEM- 243

Human   261 CPMPVTPE---ILSDSEE--------------DRVSS--NTNSYDY-----GDEYRPLFFYQETT 301
                 |||   .||:.|.              :|.:|  |.|...|     |...| :...::.|
  Fly   244 -----TPEKRKRLSELERNQAIYTRDMEVEIFERTNSGPNINKIRYTTLRMGRSTR-ISLDRKAT 302

Human   302 AQILVR---------------ALNPLDYMKWRRKSAYWKALKVFKLPVEFLLLLTVPVVDPDKDD 351
            ..:|..               ||.|::..|||:.:...:|..:.|:|...:..:.:|:||.:.|.
  Fly   303 RMVLHNRALGRNWGLFKDLFIALRPINCEKWRKGNIIKRAFMLTKIPAVIICCIYIPLVDYELDK 367

Human   352 QNWKRPLNCLHLVISPLVVVLTL-----------------QSGTYGVYEIGGLVPVWVVVVIAGT 399
            ..|.:.|||:.::::|.:.::.:                 :...|.:|.:...||:.|.:
  Fly   368 HGWNKLLNCIQVMLNPAMSIMAIKALLSSRGNSLWYVAMGEEAIYAMYSLPITVPIAVFM----- 427

Human   400 ALASVTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLA 464
                  |..:....||..|.:|..:....|...|...|||:..:|..:|.:.::.:..:|.|:.|
  Fly   428 ------FIQSRTDVPPFYHSVFTVMNLTGSMFMIFICATEIDKVLEVIGHILKVEDDFMGATVKA 486

Human   465 WGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVG--------LGCLLQISRSHTEVKLE 521
            ...|:|...::..:|..||||||:::..||..|.:::...        .|  |.:|.::.....
  Fly   487 CTGSLGPLIANVAMALHGYPRMAYASAIGGPFFTVVMSASTVMHVKNLFG--LPVSEANQTGNY- 548

Human   522 PDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVALLTEFGVIH 580
              ||..::.   |.|.:..:|:......|...|..|...::||..:|:.|:|....|||
  Fly   549 --GLNAFIF---LNLGVFSTLLWSTTLGFFARRSVGIFSIVFYCIYLLFAILIHRKVIH 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC8B1	NP_079235.2	PLN03151	63..584	CDD:215604	140/615 (23%)
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	135/605 (22%)