Protein Alignment FOXRED2 and Fmo-1

DIOPT Version :10

• Sequence 1: NP_079231.4
• Gene: FOXRED2 / 80020
• HGNCID: 26264
• Length: 684
• Species: Homo sapiens
• Sequence 2: NP_611859.1
• Gene: Fmo-1 / 37814
• FlyBaseID: FBgn0034943
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 74/342 - (21%)
• Similarity: 126/342 - (36%)
• Gaps: 92/342 - (26%)

Human    34 CVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHD 98
            |::|||.|||..|......|.:..|||.:.|.|..:           :....||..|........
  Fly     5 CIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTW-----------VYNEATGAVNGIDVHSSM 58

Human    99 WNSLLSHDPRLLFRHYSRAYFPD------------ARDMVRYLGDFADTLGLR--VQYNTTIAHV 149
            :.:|.::.|:.:..      |||            :.::..:|..:|:...|:  :::::.:..|
  Fly    59 YKNLRTNLPKEVMG------FPDFEIGANEASYVRSDEICDFLNQYANHFDLKKHIKFDSYVIRV 117

Human   150 TLDKDRQAWNGHYFILTDQKGQVHQCSVLFVATG-LSVPNQVDFPGSEYAEGYESVSVD---PED 210
            ...|.:  |...:..|...|.:......:.||.| ...||....|..|..:|....|.|   .|.
  Fly   118 LQRKTK--WQVLFKDLVTNKIEFQYFDKVLVANGHYHTPNYSQIPNMERFKGQFLHSHDFRSREV 180

Human   211 FVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSL 275
            |.|::||::|.|.|..:.: ||:..|       ..||.:|   |::.|:.  .:...:..|.|
  Fly   181 FEGKSVLVIGAGPSGMDLS-NIISRT-------ADRVTIS---HHLTDIG--QHSFFENVQQK-- 230

Human   276 DGLLESDLTDLAILKDSKGKFHVTPKFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLG 340
                 .|:.:|    |.||.|.|...:                 |:          :|.|..|.|
  Fly   231 -----PDVREL----DEKGAFFVDGSY-----------------QE----------FDTVFFCTG 259

Human   341 WNFDFSIFNKSLRLNSG 357
            :.:.|..    |.::||
  Fly   260 YKYAFPF----LTVDSG 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FOXRED2	NP_079231.4	CzcO	26..>245	CDD:441675	51/228 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	649..684
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	681..684
Fmo-1	NP_611859.1	PLN02172	4..373	CDD:215116	74/342 (22%)