DRSC/TRiP Functional Genomics Resources

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Protein Alignment WWC2 and yki

DIOPT Version :10

Sequence 1:NP_001397793.1 Gene:WWC2 / 80014 HGNCID:24148 Length:1216 Species:Homo sapiens
Sequence 2:NP_001350857.1 Gene:yki / 37851 FlyBaseID:FBgn0034970 Length:418 Species:Drosophila melanogaster


Alignment Length:112 Identity:37/112 - (33%)
Similarity:57/112 - (50%) Gaps:28/112 - (25%)


- Green bases have known domain annotations that are detailed below.


Human     3 RRAGSGQLPLPRGWEEARDYDGKVFYIDHNTRRTSWIDPR------------DRL---------- 45
            |:.|:    ||.|||:|:..||:::|::|.|:.|.|.|||            :|:          
  Fly   261 RQLGA----LPPGWEQAKTNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQNDVLQTTK 321

Human    46 -TKPLSFADCVGDELPWGWEAGFDPQIGVYYIDHINKTTQIEDPRKQ 91
             |...:.|:.:| .||.|||........:|:|:||::||...|||.|
  Fly   322 QTTTSTIANNLG-PLPDGWEQAVTESGDLYFINHIDRTTSWNDPRMQ 367

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
WWC2NP_001397793.1 WW 12..41 CDD:459800 13/28 (46%)
WW 59..88 CDD:459800 11/28 (39%)
Smc <173..>430 CDD:440809
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 441..462
C2_Kibra 700..823 CDD:176062
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 873..895
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 935..1015
Interaction with PRKCZ. /evidence=ECO:0000269|PubMed:24682284 1055..1074
PRK10929 1103..>1185 CDD:236798
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1148..1167
ykiNP_001350857.1 HUL4 <261..>404 CDD:227354 37/112 (33%)
WW 266..295 CDD:459800 13/28 (46%)
WW 335..364 CDD:459800 11/28 (39%)
Blue background indicates that the domain is not in the aligned region.

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