DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SVEP1 and svep1

DIOPT Version :9

Sequence 1:	NP_699197.3	Gene:	SVEP1 / 79987	HGNCID:	15985	Length:	3571	Species:	Homo sapiens
Sequence 2:	XP_012808841.2	Gene:	svep1 / 100493788	XenbaseID:	XB-GENE-5996067	Length:	3695	Species:	Xenopus tropicalis

Alignment Length:	3716	Identity:	2275/3716 - (61%)
Similarity:	2792/3716 - (75%)	Gaps:	174/3716 - (4%)

- Green bases have known domain annotations that are detailed below.

Human     1 MWPRLAFCCWGLALVSGWATFQQMSPS-RNFSFRLFPETAPGAPGSIPAPPAPGDEAAGSRVERL 64
            :|.  :|||. ::||..|.|:....|| |:.|.::...|        .:......|...::||:|
Frog     3 LWG--SFCCC-ISLVCSWTTYSHQLPSYRSSSSQIVQFT--------DSRKQQSSETTENKVEKL 56

Human    65 GQAFRRRVRLLRELSERLELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPVVPTATRVAIVTFSS 129
            ||.|::.:|.|||.|..|:||||||:|||||..||.:||.||:||||||||||:||||||:||||
Frog    57 GQYFKKNIRRLREKSLSLDLVFLVDESSSVGHSNFVNELRFVKKLLSDFPVVPSATRVAIITFSS 121

Human   130 KNYVVPRVDYISTRRARQHKCALLLQEIPAISYRGGGTYTKGAFQQAAQILLHARENSTKVVFLI 194
            |..|..||||||:....||||:||.:|||||:|:||||:||||||||||||.::|.|||||:|||
Frog   122 KTNVQTRVDYISSSEPHQHKCSLLNREIPAITYKGGGTFTKGAFQQAAQILRYSRSNSTKVIFLI 186

Human   195 TDGYSNGGDPRPIAASLRDSGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRA 259
            |||||||||||||||:|||.||||||.||||||||||:||||.||||||||||||.|||||||||
Frog   187 TDGYSNGGDPRPIAANLRDLGVEIFTVGIWQGNIRELHDMASHPKEEHCYLLHSFAEFEALARRA 251

Human   260 LHEDLPSGSFIQDDMVHCSYLCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACP 324
            |||||||||:||:|:.||||||:.||||||.|.|||||||||.:||||||||||||||:||||||
Frog   252 LHEDLPSGSYIQEDISHCSYLCEAGKDCCDVMASCKCGTHTGQYECICEKGYYGKGLQHECTACP 316

Human   325 SGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYF 389
            .|||||||:|||.|:||.|||.||||||||||.:||||::||...|..|::||||.|:|||||||
Frog   317 PGTYKPEGTPGGASTCITCPDPNHTSPPGSTSVDDCVCKQGYEVEGSVCKVVHCPELRPPENGYF 381

Human   390 IQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTR 454
            :||.|||||:||||:||..|:|||||:|.||.|||||:||::.|||||||.|...:||.::||:.
Frog   382 VQNICNNHFDAACGIRCKTGYDLVGSNIRLCQPNGLWTGSDATCRVRTCPKLHTLEHGRMNCSSS 446

Human   455 EMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPA 519
            :..|.|.|:..|::||.||||.||.|.|:||||...|:|.|.||..|..|..|:.||.|||::||
Frog   447 DTSYGTMCIAYCNDGYVLEGSSKLLCLGSSQWDSKVPQCKEMHCPVFHKPNGVLSSPSNCGQEPA 511

Human   520 KFGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAKTLEQQDSA 584
            |:|..|:|.|.:||:|||||:.::|..:|||:..:|.|:|||.|.|:|.||:||..:..|.|:||
Frog   512 KYGYSCHVGCNKGFMLSGVKDKIKCVANGKWSDDIQKAMCKDTEPPKIICPEDIHVENAEHQNSA 576

Human   585 NVTWQIPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAIVYTATDLSGNQASCIFHIKVIDAEPPV 649
            .:.|::|.|.|||||:||:.|.|||.|||:||||:|::.|||||:|||:|||.|:|:|||.:|||
Frog   577 LINWKVPEAVDNSGEEVSIQVSPAFLPPYVFPIGEVSVTYTATDVSGNEASCTFNIRVIDVDPPV 641

Human   650 IDWCRSPPPVQV--SEKVHAASWDEPQFSDNSGAELVITRSHTQGDLFPQGETIVQYTATDPSGN 712
            ||.|||||.:||  :||..:|||:|||||||||..|:||::|:.|||||.|.|:|||||.|||||
Frog   642 IDRCRSPPTIQVTGNEKFQSASWEEPQFSDNSGLPLIITQTHSPGDLFPVGRTVVQYTAIDPSGN 706

Human   713 NRTCDIHIVIKGSPCEIPFTPVNGDFICTPDNTGVNCTLTCLEGYDFTEGSTDKYYCAYEDGVWK 777
            .:||||:|.||||||||||||.||:..|..|..||||||.|.|||...||||...|||:.||:||
Frog   707 KKTCDIYITIKGSPCEIPFTPQNGELACLKDVEGVNCTLVCKEGYALAEGSTQNLYCAFRDGLWK 771

Human   778 PTYTTEWPDCAKKRFANHGFKSFEMFYKAARCDDTDLMKKFSEAFETTLGKMVPSFCSDAEDIDC 842
            |....:||||:..||||||||||||.|||.||||..|:|.|::||:::|||||||||:||:||:|
Frog   772 PPKRADWPDCSLNRFANHGFKSFEMLYKATRCDDNSLLKNFADAFQSSLGKMVPSFCTDADDIEC 836

Human   843 RLEENLTKKYCLEYNYDYENGFAIGPGGWGAANRLDYSYD-DFLDTVQETATSIGNAKSS----- 901
            |||:.. ::.||||||||||||||||.||||||:|||||| ||.|     ||...:|:..
Frog   837 RLEDQY-QRQCLEYNYDYENGFAIGPAGWGAANKLDYSYDEDFFD-----ATETEDAEKPLSDSP 895

Human   902 -----RIKR----SAPLSDYKIKLIFNITASVPLPDERNDTLEWENQQRLLQTLETITNKLKRTL 957
                 |:||    :|..:|.|:|.|||||||||||.:||||||.|||||||.||||:||:|||.|
Frog   896 HTAPLRVKRHRRLNAGAADQKVKFIFNITASVPLPKQRNDTLEQENQQRLLLTLETLTNRLKRIL 960

Human   958 NKDPMYSFQLASEILIADSNSLETKKASPFCRPGSVLRGRMCVNCPLGTYYNLEHFTCESCRIGS 1022
            .|:|::||..:||::||||||||..||..||||||||:||||||||.||||:|||..||||..||
Frog   961 RKEPLHSFHFSSEMIIADSNSLEDGKAFLFCRPGSVLKGRMCVNCPKGTYYSLEHRACESCWTGS 1025

Human  1023 YQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQCKQGTYSYSGLETCESCPLGTYQPKFGSRSCL 1087
            |||||||::||.||:|.||||:||:.||:||||||.||||.:|||||||||.|||||.|||::|.
Frog  1026 YQDEEGQMDCKSCPAGTYTEYLHSKRISECKAQCKPGTYSSNGLETCESCPHGTYQPVFGSKACE 1090

Human  1088 SCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFA 1152
            .||...||||||:|:.|.|||||..|:|||:||:||:|||||||||..||::||:|||||||..:
Frog  1091 VCPNGMSTVKRGSVDKSECGVPCHAGEFSRTGLVPCYPCPRDYYQPEPGKSYCLSCPFYGTTTIS 1155

Human  1153 GSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVC 1217
            |:|||.:||||.|:||||||||:.|.|..::..::::|||||:||..|||.|||||.|:|.||:|
Frog  1156 GARSIADCSSFGSSFSAAEESVMIPISPENVNSKYKVSSQVFNECLLNPCQNSGTCTQIGSGYIC 1220

Human  1218 LCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKG 1282
            .|..||||.|||.:|:|||.:||.|||:|.|.||||.|:|.||::|..||||||||||:||||:.
Frog  1221 SCIKGYTGAKCENEINECSSIPCRNNGICIDRVGEFDCQCLSGFSGTLCEENINECSSNPCLNEA 1285

Human  1283 ICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVD 1347
            ||:||:..:.|.|..||:|..||.|::||.|.|||||.||:|...||.|.||.|:.|..|.|::|
Frog  1286 ICIDGINAFYCRCANGFLGPRCEIEIDECLSRPCLNNGVCDDLKAGFQCLCPAGYTGKVCEKDID 1350

Human  1348 ECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPG 1412
            ||||.||||||:|.||.|||||.|..||||..||:|:::|.||||.|.|||||.||||.||||||
Frog  1351 ECLSGPCKNGASCTDGINSFRCQCPEGFTGQVCEINVDDCVSNPCLNNATCVDGLNSYICKCQPG 1415

Human  1413 FSGKRCETEQSTGFNLDFEVSGIYGYVMLDGMLPSLHALTCTFWMKSSDDMNYGTPISYAVDNGS 1477
            :||.||||||..|||||||||||||||:||.::|:|.|:||.|||:|||..|||||||||:||||
Frog  1416 YSGIRCETEQPFGFNLDFEVSGIYGYVLLDNVMPTLSAITCAFWMRSSDTTNYGTPISYALDNGS 1480

Human  1478 DNTLLLTDYNGWVLYVNGREKITNCPSVNDGRWHHIAITWTSANGIWKVYIDGKLSDGGAGLSVG 1542
            ||..|||||||||||:||:||||:||||||.:|||||:|||:.:|.||||||||.||||.|||||
Frog  1481 DNAFLLTDYNGWVLYINGKEKITDCPSVNDAKWHHIAVTWTNTDGSWKVYIDGKQSDGGKGLSVG 1545

Human  1543 LPIPGGGALVLGQEQDKKGEGFSPAESFVGSISQLNLWDYVLSPQQVKSLATSCPEELSKGNVLA 1607
            ..|||||||||.||||::||||:||||||||:||||:||:.|:|.|:||||.|||.||.||||||
Frog  1546 ESIPGGGALVLAQEQDQRGEGFNPAESFVGSLSQLNIWDHPLTPAQIKSLAISCPVELQKGNVLA 1610

Human  1608 WPDFLSGIVGKVKIDSKSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYC 1672
            |.|||.|:||:||:|.||.||:|||.|.|:.|||.....|.|||||::|||:||||:||.|.:.|
Frog  1611 WADFLPGVVGRVKVDHKSKFCADCPALEGTSPHLHATKSDHKPGSKISLFCNPGFQIVGKPERQC 1675

Human  1673 LNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWN 1737
            ||.|:|.||||||||||||.||.|||||::|:|.:||||||||||.|||||||||||||||||||
Frog  1676 LNLGEWDQPLPHCERISCGKPPRLENGFYNAEDLFAGSTVTYQCNIGYYLLGDSRMFCTDNGSWN 1740

Human  1738 GVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSG 1802
            |:||||||||||.:||||.|||||:|.:|||||:|:|||.||||.|.||:|||.||..|||:.||
Frog  1741 GISPSCLDVDECEIGSDCDEHASCMNTNGSYICTCIPPYHGDGKKCLEPVKCKDPGEIENGNYSG 1805

Human  1803 EIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGS 1867
            ..:.||:::.|||.|||.|:|:.|:||||||||:..:|||:||||||...|.||.|....||||.
Frog  1806 NHFGVGSQLMFSCHEGYDLIGLVKVTCLESGEWDDALPYCQAVSCGKVPAPNNGEILGSNFTFGE 1870

Human  1868 KVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCD 1932
            .||:|||:||||.|::|:.||||.||||:.|.||.|.||.|:.|.||.:.|||||:.|||||:|.
Frog  1871 IVTFRCNEGYTLIGNEETVCLANRSWSHALPTCESVTCSKPKEIENGIFSLSGLTFNSTASYACK 1935

Human  1933 TGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAG 1997
            ||||||||:.:.|.|||.|....|:|.||.||.||.::||..||:|:|:.|.:||.|||||||.|
Frog  1936 TGYSLQGPATLICEASGNWSSEVPSCDLVSCGPPPLVRDADATGDNYTYSNIITYKCKEGYTLVG 2000

Human  1998 LDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCN 2062
            .|||.|.:.||||....||:||||||||.||:||..::||||||.|:||||||||:.||:|:|||
Frog  2001 PDTINCSSSGKWSEHIPQCMAVSCDEPPNVDYASSHSSHRLFGDTAYYYCSDGYSMVDNAQMLCN 2065

Human  2063 AQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECM 2127
            .:|.||||:|:::|.|||.|||:|.||::||||||:||||.:||.|||||||||||||:|:|||:
Frog  2066 TEGNWVPPDGKEIPNCIADFCERPSSVAHSILESVNKAKFVSGSTVSFKCMEGFVLNTTARIECV 2130

Human  2128 RGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQW 2192
            |||||.||.::||||||||||||||.|||.||:|||||::|||||:||:|||||||.||.|:|:|
Frog  2131 RGGQWIPSSLTIQCIPVRCGEPPSIKNGYVSGTNYSFGSVVAYSCDKGYYIKGEKKRTCLASGEW 2195

Human  2193 SSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPL 2257
            |..:|.|||.||.:|||:||||::..||.::||:|.|.||||||.|||.|.|||.||||:||||.
Frog  2196 SGRLPACHPGSCDDPPKLENGFVKSKTGLLYESKVIYACNPGYKLVGSNVRVCQLNRHWYSESPP 2260

Human  2258 MCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAK 2322
            .||.|.|.||||::.|.||||||||||||:|||.:||||.||.||||||:|:|:||..|.|||:|
Frog  2261 TCVLLTCEKPPPVKYGSMKGENFEVGSKVEFFCEDGYELSGDLSWTCQKNGEWDKKQTPTCMPSK 2325

Human  2323 CPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLI 2387
            |.:|||.||.|||||:..|||:|.|||||||||:|.||||||||||||||||:||:|.|:.||.:
Frog  2326 CQDPPLYENHLVLKEVPNEVGIVRFSCKEGHVLEGSSVLKCLPSQQWNDSFPLCKLVFCSSPPEL 2390

Human  2388 SFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIID 2452
            ::|.||...:|:|||||||:||.||.|:|.|...|...|.||...|.|.|:||||||||.|||:|
Frog  2391 AYGEPISVPSLYFGSTVKYTCVDGFLLKGESVITCNASGMWSPDFPNCSPIECPQPEEILNGIVD 2455

Human  2453 VQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYG 2517
            ||||.:||.||||||||:||:||:|.:||.:|:|.||||.||.|:|.|.|||||||||:..|:||
Frog  2456 VQGLTFLSAALYTCKPGYELIGNSTLICGADGYWQGGKPICKPIKCSKAKEILNGKFSFQSLNYG 2520

Human  2518 QTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSC 2582
            ||:||:|||||||||.:.|||||||:|:.:.|.|..|.||.||.|:|||||||||||||:||:||
Frog  2521 QTITYTCNRGFRLEGQNVLTCLETGEWNSNPPICKEITCDPPQGIDNGFVEGADYSYGAMIIFSC 2585

Human  2583 FPGFQVAGHAMQTCEESGWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQE---DDMMEVP 2644
            .||||:.|.|||||||||||||.|.|:..|||||||||||..|.:.     ||::   ||.::
Frog  2586 MPGFQLVGLAMQTCEESGWSSSTPVCLHTDCGLPPHIDFGQYTIVT-----FEEKILTDDELK-- 2643

Human  2645 YVTPHPPYHLGAV---AKTWENTKESPATHSSN-----FLYGTMVSYTCNPGYELLGNPVLICQE 2701
                |..:.:..:   ..|..||.:: ..||.|     :||||.|.|:||.|||:||..||.|:|
Frog  2644 ----HSIFGVSNIILSPTTTSNTLKT-ENHSENSQLSEYLYGTNVIYSCNNGYEILGMSVLTCKE 2703

Human  2702 DGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGA 2766
            |||||||||:|..|||.:||.||||.:.:|:.::||:|.:.||||:.|.|||..:||.|::|:..
Frog  2704 DGTWNGSAPACAPIECSIPTDPENGVMHYTDNTIGSSVHFECKPGYELNGSDKSICLANKQWNNE 2768

Human  2767 SPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPV 2831
            .|:|..||||.||.:::|..:.|||||:|.::|:||.||.:.|..:||||..|.||.:||||:||
Frog  2769 IPKCVIISCKTPNKILHGYTEVSNYTYMSVIHYKCDKGYQIYGLSQRTCQISKQWDGEEPICVPV 2833

Human  2832 DCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQ 2896
            .|..||:..||:|.|:||||.|.|||.||||:.|.|...|.||.||:|||.||.|:.:.|.....
Frog  2834 SCGQPPMVINGKVIGNEYTFSKTIEYVCNEGYRLYGEEIRTCLENGNWSGTTPSCLAITCKISTT 2898

Human  2897 LANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPN 2961
            :.||...|.:.|..||:.:.|:.||.:.|.|||||.:||.|::..|||:|::|.||||:::|:.|
Frog  2899 VNNGEVTGTECGVGKEILYRCNHGYKMQGTPKLTCLNDGTWNSNAPLCEPIHCEPPEDISNGYLN 2963

Human  2962 GFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTDFDCGK 3026
            ..:|.:..:|.|.|||||::||:|:|:||:||:||||.|:||||.|.|||::.|.::|.||.||.
Frog  2964 SSNFKYNEYIHYVCFPGYEMHGSSTRQCLANGAWSGSPPTCLPCECPTPVVQNGIMSGDDFTCGH 3028

Human  3027 AARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCR 3091
            :..|:|.:||||||.||:||::.|:||||||||....||..|.||||||:.:||..|:.|.|:|.
Frog  3029 SVSIKCREGFKLLGSSELTCQSAGKWSSGFPHCGKVPCGPPPSIPNAFINGSSSTDEDAIRYNCV 3093

Human  3092 SGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDT 3156
            :||::||.|:|:||::||||:|||.|:.||||.||||.|||...:::||.|....||.:||.|..
Frog  3094 AGYIMQGKSELLCTKEGVWSKPYPNCQLLSCGLPPSVLNAVLIADSYTYGSTANYRCQDGYVMHQ 3158

Human  3157 DTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVC 3221
            |..:.||.:||.|.|..|.|.||||.|...:..|.....::.:|:.:::.|.||||..|.:.|.|
Frog  3159 DVSSKTCLEDGSWSPGDIVCVPKKCLLQSTLIQIKNDETEYDINKTITIVCKEGYTLTGPSTSTC 3223

Human  3222 QLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQ 3286
            ..||.|.|..::..|:|||||:|.:||||.|:|::|.|:.:::|||..|:|:.|..|||||.|..
Frog  3224 MNDGNWIPEVNNNICTPVSCGEPAAPEHGIVLGTRYLFKDSVLYQCNAGFEIHGPTERVCQINGL 3288

Human  3287 WS------------------GGV------------------------------------------ 3291
            ||                  .||
Frog  3289 WSDVEPQCKKISCHPPEPLENGVIHGAGYLFEDELHYSCNHGFELNGPSRRICHIDKQWIPPPPT 3353

Human  3292 --------------AI------------------------------------------CKETRCE 3300
                          |:                                          |||||||
Frog  3354 CVSVTCDSLPYIENAVYTSTGNTYTHNITFTCNFGYHLVGPPHVRCLVNGTWSKPLPQCKETRCE 3418

Human  3301 TPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPE 3365
            .|.:..||.|:.||.|.|..|.|.|..||:|||...|.||.|||||||||:||.|||||||||||
Frog  3419 VPQQPENGHAEYENVTVGSTVRYQCQNGYTLEGEDLAECTTNGTWSHPVPICKANPCPVPFVIPE 3483

Human  3366 NALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGV 3430
            ||:|:|.:|||.|.||||||:|:.|||..:||||.|||||..:.||||||||||..::|.|.||:
Frog  3484 NAILTETDFYVGQKVSIKCRKGYQLQGQAVITCNADETWTDANVKCEKISCGPPHTIQNGILRGM 3548

Human  3431 HYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWM 3495
            ::|:||::||||||||||.|..|||||||||||:||.|:|||||||||||:|:||||||||:|||
Frog  3549 YHQFGDVVTYSCYSGYMLLGSFRSVCLENGTWTAPPSCKAVCRFPCQNGGVCERPNACSCPKGWM 3613

Human  3496 GRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTG 3560
            |||||||||.|||||||||.||::|:||.||||||||.|||||||||||.|||||||.|..||:|
Frog  3614 GRLCEEPICPLPCLNGGRCTAPFRCECPNGWTGSRCHIAVCQSPCLNGGICVRPNRCQCPPSWSG 3678

Human  3561 HNCSRKRRTGF 3571
            .:|||||:..|
Frog  3679 PDCSRKRKHAF 3689

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SVEP1	NP_699197.3	VWA	84..258	CDD:278519	138/173 (80%)
		GCC2_GCC3	310..360	CDD:285001	40/49 (82%)
		CCP	378..434	CDD:153056	39/55 (71%)
		CCP	438..494	CDD:153056	26/55 (47%)
		DUF5011	560..642	CDD:295940	48/81 (59%)
		DUF5011	643..722	CDD:295940	54/80 (68%)
		O-glycosylated at one site	887..894		1/6 (17%)
		GCC2_GCC3	1005..1052	CDD:285001	33/46 (72%)
		GCC2_GCC3	1059..1106	CDD:285001	32/46 (70%)
		GCC2_GCC3	1113..1160	CDD:285001	32/46 (70%)
		EGF	1197..1225	CDD:278437	17/27 (63%)
		EGF_CA	1231..1267	CDD:238011	20/35 (57%)
		EGF_CA	1269..1305	CDD:238011	20/35 (57%)
		EGF_CA	1308..1342	CDD:238011	18/33 (55%)
		EGF_CA	1345..1381	CDD:238011	24/35 (69%)
		EGF_CA	1383..1419	CDD:238011	25/35 (71%)
		LamG	1424..1622	CDD:304605	150/197 (76%)
		Sushi	1628..1685	CDD:278512	34/56 (61%)
		CCP	1690..1743	CDD:153056	43/52 (83%)
		EGF_CA	1745..1783	CDD:214542	28/37 (76%)
		PHA02927	1789..2017	CDD:222943	132/227 (58%)
		CCP	1789..1843	CDD:153056	30/53 (57%)
		CCP	1847..1901	CDD:153056	31/53 (58%)
		CCP	1905..1958	CDD:153056	31/52 (60%)
		CCP	1963..2016	CDD:153056	29/52 (56%)
		Sushi	2021..2078	CDD:278512	37/56 (66%)
		CCP	2083..2136	CDD:153056	40/52 (77%)
		PHA02927	2137..2376	CDD:222943	170/238 (71%)
		CCP	2146..2199	CDD:153056	38/52 (73%)
		CCP	2204..2260	CDD:153056	35/55 (64%)
		CCP	2264..2318	CDD:153056	38/53 (72%)
		CCP	2323..2377	CDD:153056	41/53 (77%)
		CCP	2381..2436	CDD:153056	26/54 (48%)
		CCP	2440..2494	CDD:153056	38/53 (72%)
		PHA02927	2498..2770	CDD:222943	156/282 (55%)
		CCP	2498..2551	CDD:214478	36/52 (69%)
		CCP	2556..2608	CDD:153056	41/51 (80%)
		CCP	<2670..2713	CDD:153056	29/47 (62%)
		CCP	2717..2771	CDD:153056	24/53 (45%)
		PHA02927	2770..3003	CDD:222943	116/232 (50%)
		CCP	2775..2828	CDD:214478	26/52 (50%)
		CCP	2833..2887	CDD:153056	31/53 (58%)
		Cell attachment site. /evidence=ECO:0000255	2845..2847		0/1 (0%)
		CCP	2891..2945	CDD:153056	21/53 (40%)
		CCP	2949..3002	CDD:214478	28/52 (54%)
		Sushi	3007..3059	CDD:278512	29/51 (57%)
		CCP	3064..3118	CDD:153056	30/53 (57%)
		Sushi	3181..3231	CDD:278512	16/49 (33%)
		CCP	3241..3295	CDD:153056	28/169 (17%)
		CCP	3299..3353	CDD:153056	30/53 (57%)
		CCP	3357..3412	CDD:153056	37/54 (69%)
		CCP	3416..3469	CDD:153056	35/52 (67%)
svep1	XP_012808841.2	vWFA_subfamily_ECM	74..236	CDD:238727	126/161 (78%)
		Ephrin_rec_like	302..352	CDD:311571	40/49 (82%)
		PHA02927	<365..550	CDD:222943	104/184 (57%)
		CCP	430..486	CDD:153056	26/55 (47%)
		HYR	552..634	CDD:367105	48/81 (59%)
		DUF5011	646..716	CDD:383419	46/69 (67%)
		Ephrin_rec_like	1008..1055	CDD:311571	33/46 (72%)
		Ephrin_rec_like	1062..1109	CDD:311571	32/46 (70%)
		Ephrin_rec_like	1116..1163	CDD:311571	32/46 (70%)
		EGF_CA	1198..1232	CDD:238011	21/33 (64%)
		EGF_CA	1235..1270	CDD:238011	20/34 (59%)
		EGF_CA	1272..1308	CDD:238011	20/35 (57%)
		EGF_CA	1311..1346	CDD:238011	18/34 (53%)
		EGF_CA	1348..1384	CDD:238011	24/35 (69%)
		EGF_CA	1386..1422	CDD:238011	25/35 (71%)
		LamG	1422..1625	CDD:389952	154/202 (76%)
		Sushi	1631..1688	CDD:365861	34/56 (61%)
		CCP	1693..1746	CDD:214478	43/52 (83%)
		EGF_CA	1748..1786	CDD:214542	28/37 (76%)
		PHA02927	<1791..1961	CDD:222943	100/169 (59%)
		PHA02639	1904..>2082	CDD:165022	107/177 (60%)
		PHA02927	2081..2322	CDD:222943	170/240 (71%)
		PHA02817	2321..>2439	CDD:165167	74/117 (63%)
		PHA02927	2404..2612	CDD:222943	141/207 (68%)
		PHA02927	2518..2773	CDD:222943	144/266 (54%)
		CCP	2777..2830	CDD:214478	26/52 (50%)
		PHA02927	2830..3061	CDD:222943	119/230 (52%)
		CCP	3066..3119	CDD:214478	30/52 (58%)
		PHA02927	3119..3355	CDD:222943	79/235 (34%)
		PHA02927	3257..3470	CDD:222943	54/212 (25%)
		PHA02927	3366..3586	CDD:222943	117/219 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	391	1.000	Domainoid score	I6252
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23386
Inparanoid	1	1.050	4724	1.000	Inparanoid score	I76
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG38874
OrthoDB	1	1.010	-	-		D259668at32523
OrthoFinder	1	1.000	-	-		FOG0009719
OrthoInspector	1	1.000	-	-		oto149363
Panther	1	1.100	-	-	LDO	PTHR19325
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4809
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.080