Protein Alignment ERMP1 and CG11961

DIOPT Version :10

• Sequence 1: NP_079172.2
• Gene: ERMP1 / 79956
• HGNCID: 23703
• Length: 904
• Species: Homo sapiens
• Sequence 2: NP_725876.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Alignment Length: 843
• Identity: 257/843 - (30%)
• Similarity: 436/843 - (51%)
• Gaps: 66/843 - (7%)

Human    95 LVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEVQSNSLHKISV 159
            |.::....|..:|.|.:|...|..:.|:|||..||.:||:..:..|.:  |:.:::|.:.:.|.|
  Fly    82 LTIQDEETHPDQFIAERAEKNLRELVSLGPRVVGSRQNEMAALKMLSQ--KMQKIRSGTANDIEV 144

Human   160 DVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRD-GAQHAVLANCHFDSVANSPGASDDAVSCS 223
            |||..:||:   ......:.|.:|.|:|||:.|:: .:...:|.|.|:|||...|||.||....:
  Fly   145 DVQVASGSY---VHWSMVNMYQSIQNIVVKISPKNTNSTTYLLVNSHYDSVPAGPGAGDDGSMVA 206

Human   224 VMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLIRAFINLEAAGVGGKELV 288
            .|:||||||:.|.:.|.:.|:|||||||||.|||||.|||||.||...:|.|||::.|.||:|::
  Fly   207 TMMEVLRVLAKSDKPLKNPVVFLFNGAEENPLQASHAFITQHKWAKYCKALINLDSCGNGGREIL 271

Human   289 FQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIY 353
            ||:||.:|||::.|..|.|||:||.:.:|:||...|||||||||:||.|::||:|:|:..||::|
  Fly   272 FQSGPNHPWLMKNYRRAIKHPYASTMGEELFQHNFIPSDTDFRIFRDHGSVPGLDMAYTYNGFVY 336

Human   354 HTKYDTADRILTDSIQRAGDNILAVLKHLATSDMLAAASKYRHGNMVFFDVLGLFVIAYPSRIGS 418
            ||::|.|:.....|.|..|||:||:::.:|.|..:..::||..|:.::|||:|.|::.|....|.
  Fly   337 HTRHDKAEIFPRGSFQHTGDNLLALVRQIANSPEIENSAKYAKGHTIYFDVMGWFLVFYTETEGV 401

Human   419 IINYMVVMGVVLYLGKKFLQPKHKTGNYKKDFLCGLGITLISWFTSLVTVLIIAV----FISLIG 479
            |:|.:|.:..:...|..|......:|...:..|..:|.||:....|:|...|:.|    |:..:.
  Fly   402 ILNVIVSLVSIGICGYAFKLMSVNSGIKLEKILKKVGHTLLVQILSVVVGAILPVLLGLFMDAVH 466

Human   480 QSLSWYNHFYVSVCLYGTATVAKIILIHTLAKRFYYMNASAQYLGEVFFDISLFVHC-CFLVTL- 542
            ..|||:::.::.:.||.|.....:.::..|  .|::.......:|:   .:.|.:|| |.|:::
  Fly   467 LPLSWFSNSWLILGLYFTTFFFGLAIVPAL--YFHWTKRDKLPIGQ---RVQLLLHCHCLLLSVL 526

Human   543 ----TYQGLCSAFI---SAVWVAFPLLTKLCVHKDFKQHGAQGKFIAFYLLGMFIPYLYALYLIW 600
                |..|:.|.|:   |.::....|:..:..    |.|.....::..:::....|:::..|...
  Fly   527 TLIFTICGIRSVFVLMLSCLFYTVGLIINIAT----KLHTKDVAWVIPHIVCTVPPFVFFAYFSH 587

Human   601 AVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFINFIYLAKSTKKT---MLTLTLVCAIT 662
            ..|..|.|:.||.|..:.||:.:|........:...:.|..:.|...:|..   ::.:||:|
  Fly   588 GFFTTFIPMFGRFGENLNPDLAVAVFSVAVGFLCCGFIIPVLQLFNKSKTIICGLMGITLLC--- 649

Human   663 FLLVCSGTFFPYSSNPANPKP--KRVFLQHMTRTFHDLEGNAVKRDSGIWINGFD---YT---GI 719
            |::..:...|||     .|:.  :|..:.|..|||||.:....:::||.:|...|   ||   .:
  Fly   650 FIIAMTPIGFPY-----RPETNVQRFAVLHTKRTFHDAQNKVRRQESGYFIMPQDRRTYTVKNAV 709

Human   720 SHITPHIPEINDSIRAHCEENAPLCGFPWYLPVHFLIRKN--WYLPAPE-VSPRNPPHFRLISKE 781
            .::|     :...|.:.|::... ||.|.|.......|||  | :||.| |...|.|...|:||.
  Fly   710 INMT-----LAQRIGSDCDKEIN-CGLPLYNQRWHKTRKNSLW-IPASEPVLGENVPTVLLLSKN 767

Human   782 QTPWDSIKLTFEATGPSHMSFYVRAHKGSTLSQWSLGNGTPVTSKGGDYFVFYSHGLQASAWQFW 846
            ......|:...:.:||:||:.:::...|:.:..||........|....||:::|.|:.....:||
  Fly   768 TVSPTKIRYEMQLSGPNHMALFIQPLNGAKMMDWSFHQAPLRLSFEPPYFIYFSWGVNGDPLKFW 832

Human   847 IEVQVSEEHPEG-----MVTVAIAAHYLSGEDKRSPQLDALKEKFPDWTFPSAWVCTYDLFVF 904
            :|:    |.|.|     .:.:.:..|:...::..:|......:.||.:...:.|..:::..:|
  Fly   833 LEL----EKPNGNWNSSTLELGLGGHWNHHKELITPDFKKFLDSFPHYVDATPWPASFESRIF 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERMP1	NP_079172.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..65
		M28_Fxna_like	104..412	CDD:349872	136/308 (44%)
CG11961	NP_725876.1	M28_Fxna_like	91..395	CDD:349872	136/308 (44%)
		MFS	<539..>658	CDD:475125	23/125 (18%)