Protein Alignment ERMP1 and CG30049

DIOPT Version :10

• Sequence 1: NP_079172.2
• Gene: ERMP1 / 79956
• HGNCID: 23703
• Length: 904
• Species: Homo sapiens
• Sequence 2: NP_725142.3
• Gene: CG30049 / 246416
• FlyBaseID: FBgn0050049
• Length: 878
• Species: Drosophila melanogaster
• Alignment Length: 864
• Identity: 270/864 - (31%)
• Similarity: 423/864 - (48%)
• Gaps: 121/864 - (14%)

Human   105 GEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLI--EVQSNSLHKISVDVQRPTGS 167
            |:|...:|:..|..:..|||:..||..||:.||.:||.:::.|  |::.:..| :.||||:||||
  Fly    72 GQFVGERAQKILYELDRIGPKVVGSTANEVTTVAFLLNEVEKIRSEMRGDLFH-LEVDVQQPTGS 135

Human   168 FSIDFLGGFTSYYDNITNVVVKLE-PRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRV 231
            :.:   |..||.|..|.||||||. ....:...:|.|.|||:...||||.||.....|||||||.
  Fly   136 YVV---GTMTSIYQGIQNVVVKLSTASSNSSSYLLINSHFDTKPGSPGAGDDGTMVVVMLEVLRQ 197

Human   232 LSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLIRAFINLEAAGVGGKELVFQTGPENP 296
            :|.|.....|.::|||||||||.|||||||||||.||...:|.||||..|.||::::||:||.||
  Fly   198 MSISESEFMHPIVFLFNGAEENPLQASHGFITQHKWAPNCKAVINLEVGGNGGRDILFQSGPNNP 262

Human   297 WLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTAD 361
            |||:.|...:||||||.:|:|:||.||:||||||||:||:|||||:|:|...|||:|||.:|:.|
  Fly   263 WLVKYYKQHSKHPFASTLAEEIFQFGILPSDTDFRIFRDYGNIPGLDIAQFSNGYVYHTAFDSFD 327

Human   362 RILTDSIQRAGDNILAVLKHLATSDMLAAASKYRHGNMVFFDVLGLFVIAYPSRIGSIINYMVVM 426
            .:...::|..|:|||::::.|:.:..|...:::..|:.||||.||||.:.|....|.|:||...:
  Fly   328 VVPGRAVQNTGENILSLVRALSNASELYNTNEHSAGHAVFFDFLGLFFVTYTENTGIILNYCFAV 392

Human   427 GVVLYLG----KKFLQPKHKTGNYKKDFLCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNH 487
            ..|..:|    :.....:...|.....|...||:.|......:...|::::...:..:::::|::
  Fly   393 ASVFLVGFSLWRMSCVSEVSAGRISILFASHLGLHLAGCLLCIGLPLVMSILYDVSDRTMTYYSN 457

Human   488 FYVSVCLYGTATVAKIILIHTLAKRF---------YYMNASAQYLGEVFFDISLFVHCCFLVTLT 543
            .::.:.||....:..::|..||...|         |.|     |:|       |..||..|..||
  Fly   458 NWLVIGLYICPAIIGLVLPSTLYHSFKSDDKISHPYQM-----YVG-------LHAHCVVLSILT 510

Human   544 -----------YQGLCSAFISAVWVAFPLLTKLCVHKDFKQHGAQGKFIAFYLLGMFIPYLYALY 597
                       |..:.|.|:..:.:...|||.|        |.....::....:.....|:|..|
  Fly   511 IALTAIGLRIPYMCMISLFLYILSLLINLLTTL--------HDRGYYWVLTVQISQLFQYVYFCY 567

Human   598 LIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFINFIYLAKSTKKTMLTLTLVCAIT 662
            |.:....:|.|.:||:.....||:::|.|.|..|.....:.:..|.:.:.:...::.|.:|..|.
  Fly   568 LFYIFLVIFFPAMGRNRDSANPDMLIALICAVGTFFALGFVVPLINMFRWSTYLLICLGVVTFIL 632

Human   663 FLLVCSGTFFPYSSNPANPKPK----RVFLQHMTRTFHDLEGNAVKRDSGIWINGFDYTGISHIT 723
            .::..:|..|||       :||    ||......|.|::.:|:....|||.:   |||.....:.
  Fly   633 SMISITGVGFPY-------RPKTSVMRVNFLQTRRMFYEYDGSLSVNDSGYY---FDYQDRRALR 687

Human   724 PHIPEIND---------SIRAHCEENAPLCGFP--WYLPVHFLIRKNW--------YLPAPE--V 767
            |    :.|         |:..:|:... :||.|  |         .:|        :||..|  .
  Fly   688 P----LKDYAVNLTGLTSVDGYCDRYV-MCGIPCFW---------SSWCRGISSAAWLPRDEEVT 738

Human   768 SPRN-PPHF--RLISKEQTPWDSIKLTFEATGPSHMSFYVRAHKGSTLSQWSL--------GNGT 821
            .|.| ..:|  :.:||..:   |.:..||..||.||..|:|...|..:..||.        ...:
  Fly   739 VPGNLELNFLNKTLSKSGS---SARFEFELAGPPHMGLYIRPLDGVAVEDWSFIRTMLDQPEKYS 800

Human   822 PVTSKGGDYFVFYSHGLQASAWQFWIEVQVSEEHPEGMV-TVAIAAHYLSGEDKRSPQLDALKEK 885
            |      .|.:::|:|:.:|.::|.||...|:...:|.: .:.:..||::.:.:|..........
  Fly   801 P------PYQIYFSYGVDSSPFKFHIEFVKSDGQLDGPIFELGVVGHYVNQDFERDETTLRFIAD 859

Human   886 FPDWTFPSAWVCTYDLFVF 904
            .||:.:...|...:..::|
  Fly   860 LPDFVYTMEWPSLFMRYIF 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERMP1	NP_079172.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..65
		M28_Fxna_like	104..412	CDD:349872	151/309 (49%)
CG30049	NP_725142.3	M28_Fxna_like	71..378	CDD:349872	151/309 (49%)