Protein Alignment ERMP1 and CG30043

DIOPT Version :10

• Sequence 1: NP_079172.2
• Gene: ERMP1 / 79956
• HGNCID: 23703
• Length: 904
• Species: Homo sapiens
• Sequence 2: NP_725143.1
• Gene: CG30043 / 246412
• FlyBaseID: FBgn0050043
• Length: 878
• Species: Drosophila melanogaster
• Alignment Length: 886
• Identity: 276/886 - (31%)
• Similarity: 433/886 - (48%)
• Gaps: 105/886 - (11%)

Human    75 LGLALYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHY 139
            |.|||:...:..|......:|.:...:...|||.|.:|:.||.....|||:.|||..||:.||.:
  Fly    42 LWLALFYAIVIPLYYRLPDRLTISEESHRPGEFVAERAQQYLYTYDRIGPKVTGSYANEVTTVEF 106

Human   140 LLEQIKLIEVQSNS-LHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDG-AQHAVLA 202
            |:.:.:.|..:..| |:.:.:|||.|||.:   ......:.|..|.||:|||..:.. ::..:|.
  Fly   107 LVNETEKIRAEMRSDLYDLELDVQSPTGGY---VFNDMVNMYQGIHNVIVKLSSKSSQSESYLLL 168

Human   203 NCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPW 267
            |.||||...|||:.||.....||:||||.:|.|.....|.::|||||||||.|||||||||||.|
  Fly   169 NSHFDSKPGSPGSGDDGTMVVVMMEVLRQMSISEIPFEHPIVFLFNGAEENPLQASHGFITQHKW 233

Human   268 ASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRI 332
            |...:||||||..|.||::|:||:||.||||::.|...||||||:.:|:|:||||::|||:||||
  Fly   234 AEKCKAFINLEVGGSGGRDLLFQSGPNNPWLMKYYRQHAKHPFATTMAEEIFQSGVLPSDSDFRI 298

Human   333 YRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLK-HLATSDMLAAASKYRH 396
            :||:|||.|:|:|.|||||:|||.:||.:.:...|||.:|:|:||::: :...|::....|...|
  Fly   299 FRDYGNIAGLDIAQIENGYVYHTAFDTYENVPGRSIQNSGNNVLALVRAYSNASELYNTESDDSH 363

Human   397 GNMVFFDVLGLFVIAYPSRIGSIINYMV-VMGVVLYLGKKFLQPKHKTGNYKKD-----FLCGLG 455
            .  ||||.||||.:.|....|.::|.:: |:.:|| :|....:..|::......     ||..||
  Fly   364 A--VFFDFLGLFFVYYTETTGIVVNCVIGVLSLVL-VGCSVWRMCHQSEEASLPQISIWFLSILG 425

Human   456 ITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTATVAKIILIHTLAKRFYYMNASA 520
            :.::.:...:...|::||......:||:::...::...||....:..::|..||    ||.....
  Fly   426 LHVVGFLLCICLPLLMAVLFDAGDRSLTYFTSNWLVFGLYVCPAIIGLVLPLTL----YYTLLPN 486

Human   521 QYLGEVF-FDISLFVH----CCFLVTLTYQGLCSAF---ISAVWVAFPLLTKLCVHKDFKQHGAQ 577
            :.|.:.: ..:||..|    ....:.||..||.|.:   ||.::....||..|.  ......|..
  Fly   487 EKLSQAYQLQLSLHAHLVVQALLALILTAMGLRSQYLCLISMIFYGGALLINLV--STLHDRGYY 549

Human   578 GKFIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFINFI 642
            ...|..:|  ..:|:.|..||.:....:|.|:|||:|....||:::..:...|......:....|
  Fly   550 WVPIVMFL--QVLPFSYFCYLFYMFLVIFIPVLGRNGYSTNPDLIVGLLCGVCVFFALGFAAQLI 612

Human   643 YLAKSTKKTMLTLTLVCAITFLLVCSGTFFPYSSNPANPKPKRVFLQHMTRTFHDLEGNAVKRDS 707
            .:.:..|..:|.|.::..|..::..|...|||.   |.....|....|..|.|::.:|:..:.||
  Fly   613 NMFRWPKLILLGLGVMTFIFCMIAVSDVGFPYR---AKTNVMRANCLHTRRIFYEHDGSVSRSDS 674

Human   708 GIWIN-------------GFDYTGISHITPHIPEINDSIRAHCEENAPLCGFP--------WYLP 751
            |.:.|             ..|.||:           :.:...|::.. :||.|        |
  Fly   675 GYYFNYQDRRAFAPLEDSALDLTGL-----------EPVANRCDDYV-MCGIPCFYYSWCKW--- 724

Human   752 VHFLIRKNW--YLPAPEVSPRNPPHFRLISKEQTPWDS---IKLTFEATGPSHMSFYVRAHKGST 811
                  :.|  :||. |.....|....|.....|..:|   .:..||..||.||:.:::....:.
  Fly   725 ------RQWDGWLPR-ESEVILPGELTLDFLGYTVLESGTVARYEFELAGPPHMNLFIQPVGSAK 782

Human   812 LSQWSLGNGTPVTSKGGD--------YFVFYSHGLQASAWQFWIEVQVSEEHPEGMV---TVAIA 865
            :..||.      ..|..|        |.:|:|:|...::.:|:|::    |.|:|:.   |:.:|
  Fly   783 VDDWSF------VRKMLDEPEEFQPPYQIFHSYGTDNTSLKFFIDM----EKPDGIFDTPTLELA 837

Human   866 A--HYLSGEDKRSPQLDALKEKFPDWTFPSAWVCTYDLFVF 904
            |  |::|.|.:|..:.......|||:.....|...:..::|
  Fly   838 AVGHWVSFEYERDAEAKDFVAAFPDFVHVMEWPSIFKRYIF 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERMP1	NP_079172.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..65
		M28_Fxna_like	104..412	CDD:349872	150/310 (48%)
CG30043	NP_725143.1	M28_Fxna_like	71..377	CDD:349872	150/310 (48%)
		YfcC	<534..>615	CDD:440899	20/84 (24%)