DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SLC35E1 and slc35e1

DIOPT Version :9

Sequence 1:	NP_079157.3	Gene:	SLC35E1 / 79939	HGNCID:	20803	Length:	410	Species:	Homo sapiens
Sequence 2:	NP_998239.1	Gene:	slc35e1 / 406347	ZFINID:	ZDB-GENE-040426-2033	Length:	375	Species:	Danio rerio

Alignment Length:	387	Identity:	264/387 - (68%)
Similarity:	316/387 - (81%)	Gaps:	23/387 - (5%)

- Green bases have known domain annotations that are detailed below.

Human    25 REGARVAALCLLWYALSAGGNVVNKVILSAFPFPVTVSLCHILALCAGLPPLLRAWRVPPAPPVS 89
            |||.|:|.|||.||.:|:||||:||:||::||:||||||.||:::...||||||||.||...
Zfish    11 REGMRIAVLCLCWYTVSSGGNVINKIILNSFPYPVTVSLFHIVSIIVFLPPLLRAWGVPRTE--- 72

Human    90 GPGPSPHPSSGPLLPPRFYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIWVVLLSR 154
                         ||.|:|..|:|||||||||||||||.||||||||||||||||||||||||||
Zfish    73 -------------LPARYYRWYILPLAFGKYFASVSAHFSIWKVPVSYAHTVKATMPIWVVLLSR 124

Human   155 IIMKEKQSTKVYLSLIPIISGVLLATVTELSFDMWGLVSALAATLCFSLQNIFSKKVLRDSRIHH 219
            |||||||:||||:||||||.||||||||||||||.||:||||||||||||||||||||||:||||
Zfish   125 IIMKEKQTTKVYVSLIPIIGGVLLATVTELSFDMSGLISALAATLCFSLQNIFSKKVLRDTRIHH 189

Human   220 LRLLNILGCHAVFFMIPTWVLVDLSAFLVSSDLTYVYQWPWTLLLLAVSGFCNFAQNVIAFSILN 284
            |.||||||.:|:.||:|||:|||||:||:..||:.|..|..||:||.:|||||||||:||||:||
Zfish   190 LHLLNILGFNALLFMLPTWILVDLSSFLMDGDLSEVSSWTGTLMLLLISGFCNFAQNMIAFSVLN 254

Human   285 LVSPLSYSVANATKRIMVITVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQARKHLLP 349
            |||||||:|||||||||||::||:||||||.::|::||||||||||||||.|||:||:|:|.|||
Zfish   255 LVSPLSYAVANATKRIMVISISLLMLRNPVNTSNIIGMMTAILGVFLYNKAKYDSNQEAKKGLLP 319

Human   350 VTTADLSSKERHRSPLEKPHNGL-LFPQHGDYQYGRNNILTDHFQYSRQSYPNSYSLNRYDV 410
            |:..|:.|.::.:|      ||. .|....|:|:||:.:||||||||||:|..:||.::|.|
Zfish   320 VSAQDVVSFDKPQS------NGTGAFTHSSDFQHGRSTVLTDHFQYSRQAYTANYSSSQYVV 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SLC35E1	NP_079157.3	TPT	29..333	CDD:308657	222/303 (73%)
slc35e1	NP_998239.1	TPT	14..303	CDD:281186	222/304 (73%)
		EamA	32..151	CDD:304911	93/134 (69%)
		EamA	158..303	CDD:279264	110/144 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194329265
Domainoid	1	1.000	450	1.000	Domainoid score	I3567
eggNOG	1	0.900	-	-		E1_KOG1441
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49075
Inparanoid	1	1.050	523	1.000	Inparanoid score	I6206
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG57710
OrthoDB	1	1.010	-	-		D1453018at2759
OrthoFinder	1	1.000	-	-		FOG0000579
OrthoInspector	1	1.000	-	-		oto42281
orthoMCL	1	0.900	-	-		OOG6_101650
Panther	1	1.100	-	-	LDO	PTHR11132
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5824
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	1	1.500	-	-
	17	17.310