Protein Alignment COQ8B and COQ8

DIOPT Version :10

• Sequence 1: NP_079152.3
• Gene: COQ8B / 79934
• HGNCID: 19041
• Length: 544
• Species: Homo sapiens
• Sequence 2: NP_011396.1
• Gene: COQ8 / 852758
• SGDID: S000003087
• Length: 501
• Species: Saccharomyces cerevisiae
• Alignment Length: 468
• Identity: 193/468 - (41%)
• Similarity: 276/468 - (58%)
• Gaps: 25/468 - (5%)

Human    55 GEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGV----LAEMAKKSM 115
            |||::.|..|...:        |..:...||.||||||.::|.||.|:|:..    ::|:||
Yeast    49 GEENVERKHEEEKK--------DTLKSSSVPTSRISRLFHYGSLAAGVGMNAAAKGISEVAK--- 102

Human   116 PGGRLQSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVR 180
                    |.|....|..||::|.:||......:||.|||:||:||.||...:..:|..|..||:
Yeast   103 --------GNSPTWKSLILSDSNIDRITNKFSKMRGVALKIGQLLSFQDEKVLPKELYEILSRVQ 159

Human   181 QSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQ 245
            .||:.||:.|:.:|:.:|||.:|:.|.:..:::|.|||||||||...|..|..|.|||||||:.:
Yeast   160 NSANHMPQRQLEKVMAKELGANWKTKFSKFDKIPMAAASIGQVHAAELPSGQRVVVKIQYPGVKE 224

Human   246 SIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVP 310
            ||.||:.:||.:|..|:.||.|||.::::...:.||.|||||.|||...|.|..||.:||.|.||
Yeast   225 SIDSDLNSLLMLLTASSLLPKGLFLDKTIANARTELKWECDYNREARALQKFEALLKDDPAFEVP 289

Human   311 AVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLY 375
            .|..|..|..::.|....|..:.:....||:.:|.|...::.|||.|:..|::||||||||||||
Yeast   290 HVFPEYTTDNIITMTRMEGTEIMKLPKASQETKNFISENIMRLCLEEIATFKYMQTDPNWANFLY 354

Human   376 DASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVE 440
            :..:.::.||||||||.|..:|...|.:::..|...||....:.|..|.:|||.|:::..||||:
Yeast   355 NGRTKKIELLDFGASRPFAEDFILKYRKLLTYATLRDRKGAYEMSVQLGYLTGLESQSMKDAHVD 419

Human   441 AVMILGEPFA--TQGPYDFGSGETARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLR 503
            :|:.|||||.  ....:||.....:.||:..|.::|..||||||||||:||||.:|.||.||.:.
Yeast   420 SVLTLGEPFRGDVDKSFDFKDQTVSDRIRGNIGLMLNERLCPPPEETYSLHRKFSGIFLLCARMG 484

Human   504 AHIACRDLFQDTY 516
            |.:.|..||::.:
Yeast   485 ASVHCAKLFKEIF 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
COQ8B	NP_079152.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..86		7/30 (23%)
		KxGQ motif. /evidence=ECO:0000250|UniProtKB:Q8NI60	155..158		1/2 (50%)
		ABC1_ADCK3	175..424	CDD:270872	107/248 (43%)
		AAAS motif. /evidence=ECO:0000250|UniProtKB:Q8NI60	216..219		2/2 (100%)
COQ8	NP_011396.1	ABC1_ADCK3	153..403	CDD:270872	107/249 (43%)