Protein Alignment UBXN8 and casp

DIOPT Version :10

• Sequence 1: XP_011542957.1
• Gene: UBXN8 / 7993
• HGNCID: 30307
• Length: 327
• Species: Homo sapiens
• Sequence 2: NP_611080.1
• Gene: casp / 36769
• FlyBaseID: FBgn0034068
• Length: 695
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 67/270 - (24%)
• Similarity: 116/270 - (42%)
• Gaps: 66/270 - (24%)

Human    73 TSGADFTSRNLFPPGIKDFLLL---------C-------GRILL--LLALLTLTISVTTSWLNSF 119
            :|.|..|:||:....:...:|:         |       |.|.|  ||..|..|..:....|
  Fly   473 SSNASLTARNIKLDKLPAIMLVGKSRQLGSNCEVLSVIHGNIGLDDLLTRLIETCEMFEEQL--- 534

Human   120 KSPQVYLKEEEEKNEKRQKLVRKKQQEAQGEKASRYIENVLKPHQEMKLRKLEERFYQMTGEAWK 184
               ||.:::|:|:..:.|  |:.:|..|               :||.....:.:...:...||.:
  Fly   535 ---QVEIRQEDERAARDQ--VKAEQDMA---------------YQETLQADMAKDAAKRQKEAAQ 579

Human   185 LSSGHKLGGDEGTSQTSFETSNREAAKSQNLPKPLTEFPSPAEQPTCKEIPDLPEEPSQTAEEVV 249
            |:...::     .|:.:.|.:.||:.:            ..|:|       .||:|||:......
  Fly   580 LAERKRM-----ESERAEEDARRESIR------------LVAQQ-------SLPQEPSEQETGTS 620

Human   250 TVALRCPSGNVLRRRFLKSYSSQVLFDWMTRIGYHISLYSLSTSFPRRPL-AVEGGQSLEDIGIT 313
            .:.:|.|:|:.|.|||..:.:.|.|.:::|..|:.|..|.|.:|:|||.| |:|..|:||.:.:.
  Fly   621 KIRVRKPTGDFLERRFFINNNLQDLLNFVTANGFLIEEYKLISSWPRRDLTAIESSQTLESLKLY 685

Human   314 VDTVLILEEK 323
            ....:||||:
  Fly   686 PQETVILEER 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBXN8	XP_011542957.1	Ubl1_cv_Nsp3_N-like	247..322	CDD:475130	26/75 (35%)
casp	NP_611080.1	UBA_FAF1	12..44	CDD:270596
		Ubl1_FAF1	140..215	CDD:340649
		Ubl2_FAF1	236..308	CDD:340650
		UAS_FAF1	392..530	CDD:239288	14/56 (25%)
		tolA	<531..>600	CDD:236545	18/96 (19%)
		UBX_UBXN3A	616..695	CDD:340469	27/78 (35%)