| Sequence 1: | NP_079141.2 | Gene: | NANOG / 79923 | HGNCID: | 20857 | Length: | 305 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001094251.1 | Gene: | Nanog / 414065 | RGDID: | 1303178 | Length: | 312 | Species: | Rattus norvegicus |
| Alignment Length: | 318 | Identity: | 189/318 - (59%) |
|---|---|---|---|
| Similarity: | 227/318 - (71%) | Gaps: | 22/318 - (6%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MSVDPACPQSLP-CFEASDCKESSPMPVICGPEENYPSLQMSSAEMPHTETVSPLPSSMDLLIQD 64
Human 65 SPDSSTSPKGK--QPTSAEKSVAKKEDKVPVKKQKTRTVFSSTQLCVLNDRFQRQKYLSLQQMQE 127
Human 128 LSNILNLSYKQVKTWFQNQRMKSKRWQKNNWPKNSNGVTQKASAPT-YPSLYSSYHQGCLVNPTG 191
Human 192 NLPM----------WSNQTWNNSTWSNQTQNIQSWSNHSWNTQTWCTQSWNNQAWN-SPFYNCGE 245
Human 246 ESLQSCMQFQPNSPASDLEAALEAAGEGLNVIQQTTRYFSTPQTMDLFLNYSMNMQPE 303 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| NANOG | NP_079141.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..96 | 54/97 (56%) | |
| COG5576 | 74..191 | CDD:227863 | 81/119 (68%) | ||
| HOX | 95..151 | CDD:197696 | 47/55 (85%) | ||
| Required for DNA-binding. /evidence=ECO:0000269|PubMed:25825768 | 122..151 | 26/28 (93%) | |||
| 8 X repeats starting with a Trp in each unit | 196..240 | 27/44 (61%) | |||
| Sufficient for transactivation activity. /evidence=ECO:0000250 | 196..240 | 27/44 (61%) | |||
| Sufficient for strong transactivation activity. /evidence=ECO:0000250 | 241..305 | 30/63 (48%) | |||
| Nanog | NP_001094251.1 | Homeobox | 102..154 | CDD:278475 | 44/51 (86%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83680149 | |
| Domainoid | 1 | 1.000 | 176 | 1.000 | Domainoid score | I27633 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0491 | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H78027 | |
| Inparanoid | 1 | 1.050 | 359 | 1.000 | Inparanoid score | I13801 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG34640 | |
| OrthoDB | 1 | 1.010 | - | - | D1141558at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0012535 | |
| OrthoInspector | 1 | 1.000 | - | - | otm52239 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_122116 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24327 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X7335 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 18 | 18.270 | |||||