Protein Alignment ACTR5 and Actr5

DIOPT Version :9

• Sequence 1: NP_079131.3
• Gene: ACTR5 / 79913
• HGNCID: 14671
• Length: 607
• Species: Homo sapiens
• Sequence 2: NP_780628.3
• Gene: Actr5 / 109275
• MGIID: 1924748
• Length: 608
• Species: Mus musculus
• Alignment Length: 608
• Identity: 542/608 - (89%)
• Similarity: 575/608 - (94%)
• Gaps: 1/608 - (0%)

Human     1 MAANVFPFRDARAAPDPVLEAGPVAHGPLPVPLVLDNGSFQVRAGWACPGQDPGPEPRLQFRAVC 65
            |.||||.|||||:||||||||||||.|..||||||||||||.||||||||.||||||||||||||
Mouse     1 MEANVFRFRDARSAPDPVLEAGPVAFGSQPVPLVLDNGSFQARAGWACPGPDPGPEPRLQFRAVC 65

Human    66 ARGRGGARGASGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHLGVSSQGCVDH 130
            |||||||||..||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 ARGRGGARGGPGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHLGVSSQGCVDH 130

Human   131 PIVLTEAVCNPLYSRQMMSELLFECYGIPKVAYGIDSLFSFYHNKPKNSMCSGLIISSGYQCTHV 195
            ||||||||||||||||||||||||||.|||||||||||||||||.|||::.|||||||||||||:
Mouse   131 PIVLTEAVCNPLYSRQMMSELLFECYRIPKVAYGIDSLFSFYHNVPKNALSSGLIISSGYQCTHI 195

Human   196 LPILEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILHEHSYIAEDYVEEL 260
            ||:||||||||||||||||||||||||||||||||||||||||||||||||.|||||||||..||
Mouse   196 LPVLEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILQEHSYIAEDYGAEL 260

Human   261 HKWRCPDYYENNVHKMQLPFSSKLLGSTLTSEEKQERRQQQLRRLQELNARRREEKLQLDQERLD 325
            .||:||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||:
Mouse   261 QKWQCPDYYENNVHKMQLPFSSKLLGSTLTAEEKQERRQQQLRRLQELNARRREEKLQLDQERLE 325

Human   326 RLLYVQELLEDGQMDQFHKALIELNMDSPEELQSYIQKLSIAVEQAKQKILQAEVNLEVDVVDSK 390
            ||||||||||:||||||||||||||||||||||||||||::|||||||||||||.:|||||||||
Mouse   326 RLLYVQELLEEGQMDQFHKALIELNMDSPEELQSYIQKLTLAVEQAKQKILQAEASLEVDVVDSK 390

Human   391 PETPDLEQLEPSLEDVESMNDFDPLFSEETPGVEKP-VTTVQPVFNLAAYHQLFVGTERIRAPEI 454
            |||||||.|||::||||:::||:||||||||.|||| ||||||||||||||||.|||||||||||
Mouse   391 PETPDLEPLEPTMEDVENISDFEPLFSEETPEVEKPQVTTVQPVFNLAAYHQLSVGTERIRAPEI 455

Human   455 IFQPSLIGEEQAGIAETLQYILDRYPKDIQEMLVQNVFLTGGNTMYPGMKARMEKELLEMRPFRS 519
            ||||||||||||||||||.::||||||.||:.|||||||||||.||||||||:||||||||||:|
Mouse   456 IFQPSLIGEEQAGIAETLHFVLDRYPKAIQDTLVQNVFLTGGNVMYPGMKARVEKELLEMRPFQS 520

Human   520 SFQVQLASNPVLDAWYGARDWALNHLDDNEVWITRKEYEEKGGEYLKEHCASNIYVPIRLPKQAS 584
            |||||||||||||||||||||||:||:|:..|:|||:||||||||||||||||.|||||||||||
Mouse   521 SFQVQLASNPVLDAWYGARDWALDHLEDSGAWVTRKDYEEKGGEYLKEHCASNTYVPIRLPKQAS 585

Human   585 RSSDAQASSKGSAAGGGGAGEQA 607
            |:|:.|.|.:||:|.|.|||:||
Mouse   586 RASETQTSGRGSSASGSGAGDQA 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTR5	NP_079131.3	COG5277	32..569	CDD:227602	488/537 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	584..607		12/22 (55%)
Actr5	NP_780628.3	NBD_sugar-kinase_HSP70_actin	27..570	CDD:302596	491/542 (91%)
		ACTIN	32..562	CDD:214592	480/529 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	581..605		14/23 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83954261
Domainoid	1	1.000	52	1.000	Domainoid score	I57240
eggNOG	1	0.900	-	-		E1_KOG0681
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6818
Inparanoid	1	1.050	1099	1.000	Inparanoid score	I5039
Isobase	1	0.950	-	1	Normalized mean entropy	S3096
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG54909
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005644
OrthoInspector	1	1.000	-	-		oto122268
orthoMCL	1	0.900	-	-		OOG6_104278
Panther	1	1.100	-	-	LDO	PTHR11937
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R84
SonicParanoid	1	1.000	-	-		X4046
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	18	18.240