Protein Alignment BTNL8 and side

DIOPT Version :9

• Sequence 1: NP_001035552.1
• Gene: BTNL8 / 79908
• HGNCID: 26131
• Length: 500
• Species: Homo sapiens
• Sequence 2: NP_001247334.1
• Gene: side / 43300
• FlyBaseID: FBgn0016061
• Length: 986
• Species: Drosophila melanogaster
• Alignment Length: 533
• Identity: 110/533 - (20%)
• Similarity: 178/533 - (33%)
• Gaps: 171/533 - (32%)

Human    24 PDKPVQALVGEDAAFSCFLSPKTNAEAMEVRFFRGQFSSVVHLYRDGKDQPFMQMPQYQGRTKL- 87
            |.:.|.|.:|:.....|.|:|.|:.:::::..:          ::|....|...:....|..||
  Fly    96 PARLVWAALGKTVELPCDLTPPTSQDSVKLLLW----------FKDTTGIPLYSLDSRGGNVKLA 150

Human    88 ----------------VKDSIAEGRISLRLENITVLDAGLYGCRIS-----SQSY---------- 121
                            :.|:..:.|  |::.::...|.|:|.||:.     ::::
  Fly   151 PHAAIASDLGQRLFFSIGDNPKDSR--LQINDVKPEDGGVYRCRVDFFNSPTRNFRHNLTLVVPP 213

Human   122 YQKAIWELQVSALGSVPLISITGYVDRDIQLLCQSSGWFPRPTAKWKGPQGQDLSTDSRTNRDMH 186
            .:..|::.|...:..:......||   ::.|.||..|..|.|...|.....:.:.| |.|:
  Fly   214 EEPRIFDAQGKEISQMAGPFREGY---ELFLCCQVRGGRPPPKVTWWRDDTELIGT-SHTS---- 270

Human   187 GLFDVEISLTVQENAGSISCSMRHAHLSREVESRVQIGDTFFEPISWHLATKVLGILCCGLFFGI 251
                ||...||..|                   ::.||.|..:                  |:||
  Fly   271 ----VEEGATVMVN-------------------QLLIGTTTRD------------------FYGI 294

Human   252 VGLKIFFSKFQWKIQAELDWRRKHGQAELRDARKH-AVEVTLDP---ETAHPKLCVSDLKTVTHR 312
                        :|:.     |..|...:...||. .|:|.|.|   :.|.|    ::|.|
  Fly   295 ------------RIEC-----RAQGTRLVDPVRKDVTVQVYLKPVRVKIATP----NELLT---- 334

Human   313 KAPQEVPHSEKRFTRKSVVASQSFQAGKHYWEVDGGHNKRWRVGVCRDDVDRRKEYVTLSPDHGY 377
             |.|.:|...:.:        .|:.|.|..|.:||...:...|.|..|..|..   :|.|
  Fly   335 -AGQPMPIRCESW--------GSYPAAKITWLLDGEPIRNAEVTVHSDKEDGN---ITTS----- 382

Human   378 WVLRL-------NGEHLYFTLNP----------RFISVFPRTPPTKIGVFLDYECGTISFFNIND 425
             :|.|       |.|......||          |.|.|  ..||| :.|.|..|..:........
  Fly   383 -ILTLKVTSENDNAELTCRATNPWFSGGAIEDKRIIRV--AYPPT-VSVHLANEDPSRLVTRAEG 443

Human   426 QSLIYTLTCRFEGLLRP----YIEYPSYNEQNGTPIVICPVTQESEKEASWQRASAIPETSNSES 486
            |::  |..||.:.  ||    |..:.:....:|....|..:|| .|:|::...|.....|.....
  Fly   444 QNV--TFKCRADA--RPPVTSYSWFKNGMRMSGESTEIMHLTQ-LERESAGAYACGATNTEGETR 503

Human   487 SSQAT--TPFLPR 497
            ||..|  ..|.||
  Fly   504 SSSLTLKVQFSPR 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BTNL8	NP_001035552.1	IG_like	26..131	CDD:214653	21/136 (15%)
		Ig_MOG_like	33..132	CDD:143190	20/130 (15%)
		SPRY_PRY_C-I_1	289..460	CDD:293968	45/194 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	470..500		8/30 (27%)
side	NP_001247334.1	V-set	95..211	CDD:284989	21/126 (17%)
		IG_like	100..211	CDD:214653	20/122 (16%)
		Ig	235..301	CDD:299845	25/131 (19%)
		Ig	326..408	CDD:299845	25/107 (23%)
		IG_like	329..407	CDD:214653	24/103 (23%)
		IG_like	435..511	CDD:214653	18/80 (23%)
		Ig_2	442..511	CDD:290606	18/73 (25%)
		FN3	<700..735	CDD:238020

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910