Protein Alignment ZC3H14 and zc3h14

DIOPT Version :10

• Sequence 1: NP_079100.2
• Gene: ZC3H14 / 79882
• HGNCID: 20509
• Length: 736
• Species: Homo sapiens
• Sequence 2: NP_001020695.2
• Gene: zc3h14 / 562846
• ZFINID: ZDB-GENE-041014-257
• Length: 669
• Species: Danio rerio
• Alignment Length: 780
• Identity: 345/780 - (44%)
• Similarity: 457/780 - (58%)
• Gaps: 156/780 - (20%)

Human     1 MEIGTEISRKIRSAIKGKLQELGAYVDEELPDYIMVMVANKKSQDQMTEDLSLFLGNNTIRFTVW 65
            ||||||||:|||:|||.||||.||||||||||||||||||||:..||.:|||||||||||:||||
Zfish     1 MEIGTEISKKIRTAIKRKLQEFGAYVDEELPDYIMVMVANKKNPQQMADDLSLFLGNNTIKFTVW 65

Human    66 LHGVLDKLRSVTTEPSSLKSSDTNIFDSNVPSNKSNFSRGDERRHEAAVPPLAIPSARPEKRDSR 130
            |||||:|||||..||.||..|..: .::::|:..|.  ||.|.|      .:|:.|:|.:|.:.|
Zfish    66 LHGVLEKLRSVAVEPPSLGPSVVH-SETSIPAENSR--RGAEPR------AIAVSSSRSDKAEGR 121

Human   131 VSTSSQESKTTNVRQTYDDGAA---TRLMSTVKPLREPAPSEDVIDIKPEPDDLIDEDLNFVQEN 192
            ||:|:.|::.:.      .|::   :||.|.||||.| |.:|.||||||:    :|:||  :..:
Zfish   122 VSSSAHENRASK------RGSSERPSRLTSAVKPLME-ASAEAVIDIKPD----LDDDL--ISYD 173

Human   193 PLSQKKPTVTLTYGSS------------RPSIEIYRPPAS--RNADSGVHLNRLQFQQQQNSIHA 243
            |:..     :||.|.|            ||::|..|..|.  |::|    ::|.|.:.::.
Zfish   174 PVEH-----SLTSGHSQALYSRSTAERQRPAVESSRQTADTYRSSD----ISRGQDRSERG---- 225

Human   244 AKQLDMQSSWVYETGRLCEPEVLNSLEETYSPFFRNNSEKMSMEDENFRKRKLPVVSSVVKVKKF 308
                                             :|:::|  |..|.: ||||.||.||||:|.:.
Zfish   226 ---------------------------------YRSSAE--SSRDLS-RKRKAPVASSVVRVHRG 254

Human   309 NHDG------EEEEEDDDYGSRTGSISSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVT 367
            :..|      ||||||:|||     ::|.||:|:||||:|:|||:||||||||||||||||||:.
Zfish   255 HERGLEIEDLEEEEEDEDYG-----LASKVSLPSKPERKPTLPPAKQANKNLILKAISEAQESIN 314

Human   368 KTTNYSTVPQKQTLPVAPRTRTSQEELL-AEVVQGQSRTPRISPPIKEEETKGDSVEKNQGTQQR 431
            |||:..||||:||:|||||||::.:|:. |.:...|.....::|.        |::   ..||.|
Zfish   315 KTTSQYTVPQRQTVPVAPRTRSASDEMSNAAIRLVQEHLHALTPQ--------DTL---HNTQSR 368

Human   432 QLLSRLQIDPVMAETLQMSQDYYDMESMVHA-----DTRSFILKKPKLSEEVVV-----APNQES 486
            .|.||||::  :.|........|:::.:..|     ||||||:::|::.:...:     |.||..
Zfish   369 GLASRLQLE--VPEEDSREPHEYELQVLEAARLKALDTRSFIMRQPEVEQPPPIRSRLSAVNQNE 431

Human   487 GMKTADSLRVLSGHLMQTRDLVQPDKPASPKFIVTLDGVPSPPGYMSDQEEDMCFEGMKPVNQTA 551
            ...|       :..::|.|:..:....:||||||||||||||....:|||    .|....:|.||
Zfish   432 NAPT-------TSRMVQARERAEAVGGSSPKFIVTLDGVPSPLANRTDQE----METEDELNTTA 485

Human   552 -----ASNKGLRGLLHPQQLHLLSRQLEDPNGSFSNA------EMSELSVAQKPEKLLERCKYWP 605
                 .:|...........:||..      ...|.||      ||...:|..|.:||.||||:||
Zfish   486 DLPENNNNNNTTTTTSKPAIHLRL------GADFRNACDDEVEEMDVEAVQAKRQKLPERCKFWP 544

Human   606 ACKNGDECAYHHPISPCKAFPNCKFAEKCLFVHPNCKYDAKCTKPDCPFTHVSRRIPVLSPKPAV 670
            .||:||||.||||.:.||.|||||||:||||:|||||:||||||.|.||||||||   |:..|..
Zfish   545 TCKSGDECLYHHPNTQCKVFPNCKFADKCLFIHPNCKFDAKCTKADSPFTHVSRR---LNSNPTR 606

Human   671 APPAPPSSSQLCRYFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTINVPPRHALKWIRPQTS 735
            |  ||..:|.:||:||.|||::|||||||.|||.|||.|.|||||||.:.||||.||||.:.|:|
Zfish   607 A--APALTSTVCRFFPGCKKVDCPFYHPKPCRFATQCKRADCTFYHPAVAVPPRSALKWTKTQSS 669

Human   736  735
            Zfish   670  669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZC3H14	NP_079100.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..145		20/67 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	310..350		23/45 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	398..430		4/31 (13%)
		zf-CCCH_2	601..618	CDD:464217	12/16 (75%)
		zf-CCCH_2	621..639	CDD:464217	13/17 (76%)
		zf-CCCH_2	681..698	CDD:464217	11/16 (69%)
zc3h14	NP_001020695.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..145		21/78 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	175..298		52/176 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	316..337		15/20 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	460..504		15/47 (32%)
		zf-CCCH_2	540..557	CDD:464217	12/16 (75%)
		zf-CCCH_2	560..578	CDD:464217	13/17 (76%)
		zf-CCCH_2	616..632	CDD:464217	11/15 (73%)