DRSC/TRiP Functional Genomics Resources

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Protein Alignment TLCD3A and CG17841

DIOPT Version :10

Sequence 1:XP_054173240.1 Gene:TLCD3A / 79850 HGNCID:29646 Length:369 Species:Homo sapiens
Sequence 2:NP_572622.1 Gene:CG17841 / 31965 FlyBaseID:FBgn0028480 Length:429 Species:Drosophila melanogaster


Alignment Length:412 Identity:89/412 - (21%)
Similarity:150/412 - (36%) Gaps:120/412 - (29%)


- Green bases have known domain annotations that are detailed below.


Human    63 RGPGRKRGAAGSPGAAPSASRRPEFPKPLR---------VLPWRERGRG---------------- 102
            |.|....|..|...||.....:.:..:||.         ..|.:..|||                
  Fly     5 RQPANGNGRGGGTTAAVRTEEQQQQQQPLSQDAGAKEAGSTPGKATGRGCYFSLAFSIGSMGLAC 69

Human   103 GREWP-------MSLRSPLPTSACGW-------------------GESGRRAGPGRAPCGPRTGL 141
            |..|.       :||:..|..::.|:                   |:..||.        .|..:
  Fly    70 GSLWQIPNSSDRISLQRGLVLTSLGFIYFVSLTDFCNKYLLETTHGQRFRRK--------YRLMM 126

Human   142 SARAVLLSARARLVSSVHAVLATGSGIVIIRS-C-DDVITGRHWLAREYVWFLIPYMIYDSYAMY 204
            |.   :|....::||::.|..:...|:::.:| | ...:...|:|...|.||...|.:||.::||
  Fly   127 SD---VLEITNKIVSAIQASFSFFVGLIVCKSTCTKSFVYASHFLMEAYGWFGTAYFMYDIWSMY 188

Human   205 LCEWCRTRDQNRAPSLT------------------------------------------------ 221
            .....:..|:.....:|                                                
  Fly   189 KVHTQKIADKLHLLRITKGQGAVVSNGHANGKVNGKSASGNNNGSTPTNLHEICDYDGACVQIPK 253

Human   222 -----LRNFLSRNRLMITHHAVILFVLVPVAQRLRGDLGDFFVGCIFTAELSTPFVSLGRVLIQL 281
                 ...::..:.:|:.||..|....:.|...:||. |......:|..|.|||||||..:|..:
  Fly   254 DGRWDFLKYVVTHPVMMIHHVFIGTFGLLVVTYIRGG-GHCIYSYMFMMEFSTPFVSLRSILSTM 317

Human   282 KQQHTLLYKVNGILTLATFLSCRILLFPFMYWSYGRQ-QGLSLLQVPFSIPFYCNVANAFLVAPQ 345
            :.:.:.:|..||:|.||||..||:.::|::.|.|... :..||....:.:|..|.::.|.|..||
  Fly   318 RLKDSRVYIANGLLMLATFFVCRVCMWPYVMWRYSLAIEAASLWSAMWGLPRGCLISIAILFLPQ 382

Human   346 IYWFCLLCRKAVRLFDTPQAKK 367
            :|||.|:...|:::| .||.::
  Fly   383 LYWFYLMVLGALKVF-LPQKRR 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TLCD3AXP_054173240.1 PHA03378 <49..>139 CDD:223065 21/126 (17%)
TLC 153..361 CDD:214789 62/263 (24%)
CG17841NP_572622.1 TLC 127..397 CDD:214789 64/273 (23%)

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