Protein Alignment ZDHHC11 and app

DIOPT Version :9

• Sequence 1: XP_016865358.1
• Gene: ZDHHC11 / 79844
• HGNCID: 19158
• Length: 559
• Species: Homo sapiens
• Sequence 2: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Alignment Length: 436
• Identity: 93/436 - (21%)
• Similarity: 146/436 - (33%)
• Gaps: 139/436 - (31%)

Human    44 VTWAVFVGLSSATFGIFIPFLPHAWKYIAYVVTGGIFSFHLVVHLIASCIDPA-------DSNVR 101
            :|..:..|.|:..|....|||..:......:|...::.|.:...|..:..||.       |....
  Fly    48 LTCILITGTSALFFAFDCPFLADSINPAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAY 112

Human   102 LMKNYSQPMPLFD-------RSKHAHV----IQNQFCHLCKVTVPQHPPPASHSLLDALSPGRTG 155
            :.|....|..|..       |:|...|    ::.::|..||:.   .||.||
  Fly   113 IEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIF---RPPRAS------------- 161

Human   156 LVPPRHLASSDGPLALPQPAHLGPDRRSPIHPSRNKKTKHCISCNKCVSGFDHHCKWINNCVGSR 220
                                                   ||..|:.||..|||||.|:.||||.|
  Fly   162 ---------------------------------------HCSLCDNCVDRFDHHCPWVGNCVGKR 187

Human   221 NYWFFFSTVASATAGMLCLIAILLY-VLVQYLVNPGVLRTDPRYEDVKNMNTWLLFLPLFPVQVQ 284
            ||.||:..:.|     |..:|:.:: ..|.:|    ||.....:| |.|:.....|
  Fly   188 NYRFFYLFLVS-----LAFLAVFIFSCSVTHL----VLLMKKEHE-VFNVIKAAPF--------- 233

Human   285 TLIVVIIGMLVLLLDFLGLVHLGQLLIFHIYLSMSPTLSPRSPQGWVVRAAHLTPLLEYVPNPEP 349
            |:|||.| ....:...:||..      ||.||:.|...:....:|.......        |..:.
  Fly   234 TVIVVFI-CFFSIWSVIGLAG------FHTYLTTSDQTTNEDLKGSFSSKGG--------PRTQN 283

Human   350 PTPGARVFVPRVRMCSGSASPRSEIMDKKGKSQEEIKSMRTQQAQQEAELTPRPAGVVPEAKKMT 414
            |.....:.:....:..|..:|  .::|::|.:.:|.    .||.|.::  :||.|
  Fly   284 PYSRGNICLNCCHILCGPMTP--SLIDRRGIATDEF----IQQMQHQS--SPRHA---------- 330

Human   415 TFEYLINNRKEESSKHQAVRKDPYVQMDKGVLQQGAGALGSSAQGV 460
            ..:.|       |:.|......|.:    |.|  |.|.:|.:..|:
  Fly   331 LSDVL-------SASHMVTTSQPMM----GGL--GGGGIGGAGGGI 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZDHHC11	XP_016865358.1	None
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	50/204 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810