Protein Alignment ZDHHC11 and app

DIOPT Version :10

• Sequence 1: XP_024301977.1
• Gene: ZDHHC11 / 79844
• HGNCID: 19158
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Alignment Length: 406
• Identity: 87/406 - (21%)
• Similarity: 136/406 - (33%)
• Gaps: 128/406 - (31%)

Human    44 VTWAVFVGLSSATFGIFIPFLPHAWKYIAYVVTGGIFSFHLVVHLIASCIDPA-------DSNVR 101
            :|..:..|.|:..|....|||..:......:|...::.|.:...|..:..||.       |....
  Fly    48 LTCILITGTSALFFAFDCPFLADSINPAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAY 112

Human   102 LMKNYSQPMPLFD-------RSKHAHV----IQNQFCHLCKVTVPQHPPPASHSLLDALSPGRTG 155
            :.|....|..|..       |:|...|    ::.::|..||:.   .||.||
  Fly   113 IEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIF---RPPRAS------------- 161

Human   156 LVPPRHLASSDGPLALPQPAHLGPDRRSPIHPSRNKKTKHCISCNKCVSGFDHHCKWINNCVGSR 220
                                                   ||..|:.||..|||||.|:.||||.|
  Fly   162 ---------------------------------------HCSLCDNCVDRFDHHCPWVGNCVGKR 187

Human   221 NYWFFFSTVASATAGMLCLIAILLY-VLVQYLVNPGVLRTDPRYEDVKNMNTWLLFLPLFPVQVQ 284
            ||.||:..:.|     |..:|:.:: ..|.:|    ||.....:| |.|:.....|
  Fly   188 NYRFFYLFLVS-----LAFLAVFIFSCSVTHL----VLLMKKEHE-VFNVIKAAPF--------- 233

Human   285 TLIVVIIGMLVLLLDFLGLVHLGQLLIFHIYLRSASPRSEIMDKKGKSQEEIKSMRTQQAQQEAE 349
            |:|||.| ....:...:||..      ||.|| :.|.::...|.||....: ...|||.......
  Fly   234 TVIVVFI-CFFSIWSVIGLAG------FHTYL-TTSDQTTNEDLKGSFSSK-GGPRTQNPYSRGN 289

Human   350 LT---------PRPAGVVPEAKKMTTFEYLINNRKEE----------SSKHQAVRKDPYVQMDKG 395
            :.         |....:: :.:.:.|.|::...:.:.          |:.|......|.:    |
  Fly   290 ICLNCCHILCGPMTPSLI-DRRGIATDEFIQQMQHQSSPRHALSDVLSASHMVTTSQPMM----G 349

Human   396 VLQQGAGALGSSAQGV 411
            .|  |.|.:|.:..|:
  Fly   350 GL--GGGGIGGAGGGI 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZDHHC11	XP_024301977.1	DHHC	193..316	CDD:396215	40/123 (33%)
app	NP_648561.2	DHHC	146..270	CDD:396215	51/205 (25%)