DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CLMP and Ama

DIOPT Version :9

Sequence 1:	NP_079045.1	Gene:	CLMP / 79827	HGNCID:	24039	Length:	373	Species:	Homo sapiens
Sequence 2:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	244	Identity:	54/244 - (22%)
Similarity:	98/244 - (40%)	Gaps:	48/244 - (19%)

- Green bases have known domain annotations that are detailed below.

Human    14 VGTLGTHTEIKRVAEEKVTLPCHHQLGLPEKDTLDIEWLLTDNEGNQKVVITYSSRHVYNNLTEE 78
            |.::|...|.....||         :|     .|.:.|....:|.:...|: .|.|::.:  ..:
  Fly    43 VASVGDSVEFNCTVEE---------VG-----QLSVSWAKRPSESDTNSVV-LSMRNILS--LPD 90

Human    79 QKGRVAFASNFLAGDA--SLQIEPLKPSDEGRYTCKVKNSG-RYVWSHVILKVLVRP----SKPK 136
            |:..|........|.|  :.:|:.::.||.|.|.|:|..|. ..|...:.|::...|    :.||
  Fly    91 QRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIAENTPK 155

Human   137 CELEGELTEGSDLTLQCESSSGTEPIVYYWQRIREKEGEDERLPPKSRIDYNHPGRVL------L 195
            ..|   :|||.:|.|.|.::...:|.: .|.|      |...:.|..       |.:|      :
  Fly   156 STL---VTEGQNLELTCHANGFPKPTI-SWAR------EHNAVMPAG-------GHLLAEPTLRI 203

Human   196 QNLTMSYSGLYQCTAGNEAGK-ESCVVRVTVQYVQSIGMVAGAVTGIVA 243
            :::.....|.|.|.|.|..|: :..::||.|::...|.:....:..:|:
  Fly   204 RSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVS 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CLMP	NP_079045.1	IgV_CAR_like	13..127	CDD:409552	25/115 (22%)
		Ig strand B	31..35	CDD:409552	0/3 (0%)
		Ig strand C	48..52	CDD:409552	0/3 (0%)
		Ig strand E	94..98	CDD:409552	1/5 (20%)
		Ig strand F	108..113	CDD:409552	2/4 (50%)
		Ig strand G	121..124	CDD:409552	0/2 (0%)
		IG	144..225	CDD:214652	21/87 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	264..373
Ama	NP_731114.2	I-set	33..143	CDD:254352	26/116 (22%)
		Ig	37..127	CDD:299845	22/100 (22%)
		IG_like	154..234	CDD:214653	24/96 (25%)
		IGc2	161..223	CDD:197706	17/75 (23%)
		I-set	254..330	CDD:254352
		IGc2	254..322	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910