Protein Alignment EHMT1 and CG4565

DIOPT Version :10

• Sequence 1: XP_011517323.1
• Gene: EHMT1 / 79813
• HGNCID: 24650
• Length: 1301
• Species: Homo sapiens
• Sequence 2: NP_001097743.1
• Gene: CG4565 / 41303
• FlyBaseID: FBgn0037841
• Length: 269
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 84/260 - (32%)
• Similarity: 125/260 - (48%)
• Gaps: 48/260 - (18%)

Human  1032 VDSEPCPSN----YKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMC---GQLSMRCWYDK 1089
            ::|...||:    :|:::.         :.|...|..|.|...|.:|. :|   ||..    :.:
  Fly    22 LESVLMPSDGSKEFKFLAD---------EYNSVLLNPCHCKGACENSE-VCAHGGQYE----FTE 72

Human  1090 DGRLLPEFNMAEPPLIFECNHACSCWRN-CRNRVVQNGLRARLQLYRTRDMG-WGVRSLQDIPPG 1152
            ||..|...|.|.|  :.|||..|.|.|| |.||:|.:|.|..|:::.:...| .|:|:...|..|
  Fly    73 DGSELILRNSANP--VIECNDMCKCCRNTCSNRLVYSGPRKHLEIFDSPVYGSKGLRTTAKITKG 135

Human  1153 TFVCEYVGELISDSEADVREED-------SYLFDLD----NKDGEVYCIDARFYGNVSRFINHHC 1206
            .::|||.|||::..||..|..|       :|:..|:    :|..:|..:|....||:.|::||.|
  Fly   136 GYICEYAGELLTVPEARSRLHDNEKLGLMNYILVLNEYTSDKKQQVTIVDPSRRGNIGRYLNHSC 200

Human  1207 EPN--LVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIK---GKLFSCRCGSPKC 1266
            |||  :..||:     |...|:|..|:.|.|.|.|:|.|.||......|   ||  :|.||:.||
  Fly   201 EPNCHIAAVRI-----DCPIPKIGIFAARDIAAKEELCFHYGGEGQYKKMTGGK--TCLCGASKC 258

Human  1267  1266
              Fly   259  258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EHMT1	XP_011517323.1	EHMT_ZBD	517..647	CDD:411018
		ANKYR	723..979	CDD:440430
		ANK repeat	745..771	CDD:293786
		ANK repeat	777..806	CDD:293786
		ANK repeat	808..839	CDD:293786
		ANK repeat	841..873	CDD:293786
		ANK repeat	875..906	CDD:293786
		ANK repeat	908..939	CDD:293786
		ANK repeat	941..972	CDD:293786
		SET_EHMT1	1039..1269	CDD:380933	82/253 (32%)
CG4565	NP_001097743.1	SET_SETMAR	16..267	CDD:380942	84/260 (32%)