Protein Alignment TFPI2 and tag-290

DIOPT Version :9

• Sequence 1: NP_006519.1
• Gene: TFPI2 / 7980
• HGNCID: 11761
• Length: 235
• Species: Homo sapiens
• Sequence 2: NP_505945.1
• Gene: tag-290 / 179593
• WormBaseID: WBGene00009386
• Length: 219
• Species: Caenorhabditis elegans
• Alignment Length: 216
• Identity: 53/216 - (24%)
• Similarity: 71/216 - (32%)
• Gaps: 56/216 - (25%)

Human    36 CLLPLDYG-PCRALLLR--YYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCR 97
            |..|.|.| .|......  :|:|...:.|:.|||.||.||.|.|.|.:.|.|||...:.......
 Worm    19 CTQPKDSGNVCSGSQAERSFYFDTRMKVCQPFLYSGCGGNENRFSTSKECRDACQNKKSSSTTES 83

Human    98 LQVSVDDQCEGS-------------------------------TEKYFFNLSSMTCEKFFSGGCH 131
            .....||..:.|                               ..||.....:..|.||.|
 Worm    84 PDTISDDSADQSGSPNSPPFVPQGDGHDQWRKADICGSNYLIPNGKYITCSPNQACPKFHS---- 144

Human   132 RNRIENRFPDEATCM-GFCAPKKIPSFCYSPKDEGLCSANV---TRYYFNPRYRTCDAFTYTGCG 192
                         |: |.|.|.| ...|....|.|.....|   .|:.:|....:|..::|.|..
 Worm   145 -------------CVNGACCPSK-DYVCSLRDDNGSFMDGVEDRPRFSWNNDVHSCTRWSYYGAN 195

Human   193 GNDNNFVSREDCKRACAKALK 213
            ||.|||.:.:.|.:.|..:.|
 Worm   196 GNYNNFPNFQSCMKFCQDSKK 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TFPI2	NP_006519.1	KU	34..86	CDD:238057	20/52 (38%)
		Kunitz_BPTI	95..149	CDD:278443	11/85 (13%)
		Kunitz_BPTI	157..204	CDD:278443	14/49 (29%)
tag-290	NP_505945.1	Kunitz_BPTI	19..73	CDD:278443	21/53 (40%)
		KU	156..211	CDD:197529	15/54 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4295
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I4351
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000145
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860