Protein Alignment ISOC2 and CG3663

DIOPT Version :10

• Sequence 1: NP_078986.1
• Gene: ISOC2 / 79763
• HGNCID: 26278
• Length: 221
• Species: Homo sapiens
• Sequence 2: NP_611952.1
• Gene: CG3663 / 37944
• FlyBaseID: FBgn0035044
• Length: 208
• Species: Drosophila melanogaster
• Alignment Length: 215
• Identity: 72/215 - (33%)
• Similarity: 122/215 - (56%)
• Gaps: 27/215 - (12%)

Human     1 MAAARPSLGRVLPGSSVLFLCDMQEKFRHNIAYFPQIVSVAARMLKVARLLEVPVMLTEQYPQGL 65
            ||..|..|.   |..::..|||:|||||..:..|..::....::.:..:.|:||:::||.||:.|
  Fly     1 MALRRCHLN---PKKTLFLLCDIQEKFRPAMPLFDNMIKNVDKLTRAGKALDVPLIVTEHYPEKL 62

Human    66 GPTVPELGTEGLRPLA-KTCFSM----VPALQQEL-DSRPQLRSVLLCGIEAQACILDPRSYPGL 124
            |.||.:|.....:.:: ||.|||    |.|:.::: :.:|:  .|:|.|:|:..|:
  Fly    63 GKTVAQLDVSHAKLVSGKTLFSMFTPEVKAVIKDIFNDKPE--DVVLYGLESHICV--------- 116

Human   125 ALTSLYPQNTTLDLLDRGLQVHVVVDACSSRSQVDRLVALARMRQSGAFLSTSEGLILQLVGDAV 189
                   :.|.:|||::.:.|::|.|.||||...||.:||.|:||:|..::|||.:|..||.|..
  Fly   117 -------EQTAIDLLEQNINVYIVADCCSSRLNQDRDLALDRLRQAGCVITTSESVIFDLVRDKN 174

Human   190 HPQFKEIQKLIKEPAPDSGL 209
            :|:|..::||:.:|:.|..|
  Fly   175 NPKFDVVRKLVNQPSVDMEL 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ISOC2	NP_078986.1	YcaC_related	17..186	CDD:238494	58/174 (33%)
CG3663	NP_611952.1	YcaC_related	14..171	CDD:238494	58/174 (33%)