Sequence 1: | NP_059108.1 | Gene: | FZD3 / 7976 | HGNCID: | 4041 | Length: | 666 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001262037.1 | Gene: | fz2 / 40090 | FlyBaseID: | FBgn0016797 | Length: | 806 | Species: | Drosophila melanogaster |
Alignment Length: | 746 | Identity: | 234/746 - (31%) |
---|---|---|---|
Similarity: | 328/746 - (43%) | Gaps: | 190/746 - (25%) |
- Green bases have known domain annotations that are detailed below.
Human 17 MGHIGGHSL------------------FSCEPITLRMCQDLPYNTTFMPNLLNHYDQQTAALAME 63
Human 64 PFHPMVNLDCSRDFRPFLCALYAPICMEYGRVTLP-CRRLCQRAYSECSKLMEMFGVPWPEDMEC 127
Human 128 SRFPDCDEP------YPRLVDL------------------------------------------- 143
Human 144 ------------NLAGEPTEGAPVAVQ-RDYGFWCPRELKIDPDLGYSFLH-------------- 181
Human 182 --VRDCSPPCPNMYFRREELSFARYFIGLISIICLSATLFTFLTFLIDVTRFRYPERPIIFYAVC 244
Human 245 YMMVSLIFFI-GFLLEDRVACNASIPAQYKASTVTQGSHNKACTMLFMILYFFTMAGSVWWVILT 308
Human 309 ITWFLAAVPKWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVDALRY 373
Human 374 FVLAPLCLYVVVGVSLLLAGIISLNRVRIEIPLE-----KENQDKLVKFMIRIGVFSILYLVPLL 433
Human 434 VVIGCYFYEQAYRGIWETTWIQERCREYHIPCPYQVTQMSRPDLILFLMKYLMALIVGIPSVFWV 498
Human 499 GSKKTCFEWASFFHGRRKKEIVNESRQVLQEPDFA---QSLLRD-PNTPIIRKSRGTSTQGTSTH 559
Human 560 ASSTQLAMVDDQRSKAGS-IHSKVSSYHGSLHRSRDGRYTPCSYRGMEERLPHGSMSRLTDHSRH 623
Human 624 SSSHRLNEQSRHSSIRDLSNNPMTHITHGTS 654 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
FZD3 | NP_059108.1 | CRD_FZ3 | 24..150 | CDD:143558 | 52/205 (25%) |
7tmF_FZD3 | 192..512 | CDD:320161 | 139/325 (43%) | ||
TM helix 1 | 201..226 | CDD:320161 | 11/24 (46%) | ||
TM helix 2 | 235..256 | CDD:320161 | 9/21 (43%) | ||
TM helix 3 | 287..313 | CDD:320161 | 15/25 (60%) | ||
TM helix 4 | 330..352 | CDD:320161 | 7/21 (33%) | ||
TM helix 5 | 366..391 | CDD:320161 | 11/24 (46%) | ||
TM helix 6 | 419..444 | CDD:320161 | 17/24 (71%) | ||
TM helix 7 | 473..498 | CDD:320161 | 10/24 (42%) | ||
Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 502..507 | 2/4 (50%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 538..666 | 24/119 (20%) | |||
fz2 | NP_001262037.1 | CRD_FZ5_like | 63..182 | CDD:143565 | 47/118 (40%) |
Frizzled | 308..618 | CDD:279827 | 139/336 (41%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X126 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.810 |