Protein Alignment PPCS and CAB2

DIOPT Version :10

• Sequence 1: NP_078940.2
• Gene: PPCS / 79717
• HGNCID: 25686
• Length: 311
• Species: Homo sapiens
• Sequence 2: NP_012183.2
• Gene: CAB2 / 854726
• SGDID: S000001345
• Length: 365
• Species: Saccharomyces cerevisiae
• Alignment Length: 300
• Identity: 115/300 - (38%)
• Similarity: 167/300 - (55%)
• Gaps: 46/300 - (15%)

Human    36 RVVLVTSGGTKVPLEARPVRFLDNFSSGRRGATSAEAFLAAGYGVLFLYRARSAFPYAHRFPPQT 100
            ::||:|||||.||||...|||:||||:|.|||:|||.|||.||.|:||:|..|..||...|
Yeast    74 KIVLITSGGTTVPLENNTVRFIDNFSAGTRGASSAEQFLANGYSVIFLHREFSLTPYNRSF---- 134

Human   101 WLSALRPSGPALSGLL--SLEAEENALPGFAE-ALRS------YQEAAAAGTFLAVEFTTLADYL 156
                    ..:::.|.  .:::|....|.||| .|::      |.|...  ..|.:.|||:..||
Yeast   135 --------SHSINTLFLDYIDSEGKIKPEFAENVLKNKKLYDKYMEKEE--KLLLLPFTTVNQYL 189

Human   157 HLLQAAAQALNPLGPSAMFYLAAAVSDFYVPVSEMPEHKIQSS-------------------GGP 202
            ..|::.|:.||..|  .:||||||||||:||.|.:|:|||||.                   .|.
Yeast   190 WSLKSIAKLLNNSG--CLFYLAAAVSDFFVPYSRLPQHKIQSGDNGKMGANNDTEGTTRTTPDGK 252

Human   203 LQITMKMVPKLLSPLVKDWAPKAFIISFKLETDPAIVINRARKALEIYQHQVVVANILESRQSFV 267
            |.:.:..|||.|..||:.||.:|.|:|||||||.::::.:..:||:.|.||:|:.|:|::|...|
Yeast   253 LIVNLDPVPKFLRRLVESWATQAMIVSFKLETDESMLLYKCTQALDRYNHQLVIGNLLQTRNKQV 317

Human   268 FIVTKDSETKLLLSEEEIEKGVEIEEKIVDNLQSRHTAFI 307
            ..|:.::.....:..:  ||...|||.|:..:.:||..::
Yeast   318 IFVSPENRKGDWVRLD--EKHHSIEEMIIPEVIARHDKWV 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPCS	NP_078940.2	PRK05579	<15..302	CDD:235513	113/293 (39%)
CAB2	NP_012183.2	PRK05579	<72..333	CDD:235513	107/274 (39%)
		PRK06732	76..>118	CDD:475183	30/41 (73%)