DRSC/TRiP Functional Genomics Resources

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Protein Alignment PPCS and ppc1

DIOPT Version :10

Sequence 1:NP_078940.2 Gene:PPCS / 79717 HGNCID:25686 Length:311 Species:Homo sapiens
Sequence 2:NP_588072.1 Gene:ppc1 / 2539367 PomBaseID:SPCC4B3.18 Length:316 Species:Schizosaccharomyces pombe


Alignment Length:310 Identity:131/310 - (42%)
Similarity:176/310 - (56%) Gaps:12/310 - (3%)


- Green bases have known domain annotations that are detailed below.


Human     1 MAEMDPVAEF----PQPPGAARWAEVMARFAARLGAQGRRVVLVTSGGTKVPLEARPVRFLDNFS 61
            |.|||...:|    |.|......:.::..| ..|.:..:.:..||||||.||||...|||:||||
pombe     1 MPEMDKSNDFFEENPCPNSLGDVSSLIEDF-INLQSNSQNIAFVTSGGTLVPLEQNTVRFIDNFS 64

Human    62 SGRRGATSAEAFLAAGYGVLFLYRARSAFPYAHRFP-PQTWLSALRPSGPALSGLLSLEAEENAL 125
            :|.|||.|||.|..:||.|:||||..|..|:..|:. |.|.|............::..|.:....
pombe    65 AGNRGAASAEYFCKSGYSVIFLYRNYSLMPFTRRYEGPWTNLFERSNGSQEKPWIVKQEFQSTVF 129

Human   126 PGFAEALRSYQEAAAAGTFLAVEFTTLADYLHLLQAAAQALNPLGPSAMFYLAAAVSDFYVPVSE 190
                .||............:.:.:|||.:||..|:|.|:.|..:...|:||||||||||::|..|
pombe   130 ----NALNELDTYTKHHRLIMIPYTTLTEYLWYLKAIAERLQIIASRALFYLAAAVSDFHIPPKE 190

Human   191 MPEHKIQSSGG--PLQITMKMVPKLLSPLVKDWAPKAFIISFKLETDPAIVINRARKALEIYQHQ 253
            :.||||||..|  .|::.|..|||.|..||..|||:|.||||||||||:|:|::||.||:.|.||
pombe   191 LSEHKIQSGSGSNKLEVKMHPVPKFLRFLVDTWAPEASIISFKLETDPSILIDKARVALQRYNHQ 255

Human   254 VVVANILESRQSFVFIVTKDSETKLLLSEEEIEKGVEIEEKIVDNLQSRH 303
            :|:||:|.:|:..|..||..:...|.||:::|.|.||||:.||....|.|
pombe   256 LVIANLLSTRKRSVAFVTSKTVEWLHLSDDDIVKKVEIEQYIVSRAISLH 305

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PPCSNP_078940.2 PRK05579 <15..302 CDD:235513 122/289 (42%)
ppc1NP_588072.1 coaBC_dfp <43..263 CDD:273116 104/223 (47%)

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