Protein Alignment PPCS and Y71H2AM.6

DIOPT Version :10

• Sequence 1: NP_078940.2
• Gene: PPCS / 79717
• HGNCID: 25686
• Length: 311
• Species: Homo sapiens
• Sequence 2: NP_497616.1
• Gene: Y71H2AM.6 / 175394
• WormBaseID: WBGene00022171
• Length: 277
• Species: Caenorhabditis elegans
• Alignment Length: 282
• Identity: 117/282 - (41%)
• Similarity: 159/282 - (56%)
• Gaps: 38/282 - (13%)

Human    37 VVLVTSGGTKVPLEARPVRFLDNFSSGRRGATSAEAFLAAGYGVLFLYRARSAFPYAHRFPPQTW 101
            :|.:|||||:||||...|||:||||.|.|||.|||.||.|||.|:|::|..|..|::..||  ..
 Worm    19 IVFITSGGTQVPLEKNTVRFIDNFSMGTRGAASAEYFLRAGYAVIFMHREESLKPFSRHFP--NI 81

Human   102 LSALRPSGPALSGLLSLEAEENA---LPGFAEALR---SYQEAAAAGTFLAVEFTTLADYLHLLQ 160
            .::|:..|            ||.   ||..|:.||   .|:|     ..|.:.|.|...|:..|:
 Worm    82 FNSLKLDG------------ENVVCDLPNLAQILRDKFKYEE-----KILYIPFKTFDQYMSRLE 129

Human   161 AAAQALNPLGPSAMFYLAAAVSDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAPKA 225
            .....|||||..||.|||||||||.  |:|:|.||| :|...|.:.:.:.||::..:|..:.|.|
 Worm   130 QICIHLNPLGSRAMAYLAAAVSDFV--VTELPTHKI-ASNTELSLELSVAPKVIQKVVTCFIPNA 191

Human   226 FIISFKLETDPAIVINRARKALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEIEKG-- 288
            ||:|||||||...:|.:|:.||..|.||:|:||:|.:|:..|.:|.|:.|     ..|||...
 Worm   192 FIVSFKLETDETKLIPKAKAALSKYGHQLVIANMLSTRKQRVTLVRKNIE-----QGEEINLAPG 251

Human   289 ---VEIEEKIVDNLQSRHTAFI 307
               :|||..|:|.:.:.|..||
 Worm   252 APELEIESFIIDRVSALHRQFI 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPCS	NP_078940.2	PRK05579	<15..302	CDD:235513	114/275 (41%)
Y71H2AM.6	NP_497616.1	PRK05579	<20..268	CDD:235513	114/274 (42%)