Protein Alignment COLGALT1 and CG31915

DIOPT Version :10

• Sequence 1: NP_078932.2
• Gene: COLGALT1 / 79709
• HGNCID: 26182
• Length: 622
• Species: Homo sapiens
• Sequence 2: NP_723087.1
• Gene: CG31915 / 319025
• FlyBaseID: FBgn0051915
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 600
• Identity: 256/600 - (42%)
• Similarity: 357/600 - (59%)
• Gaps: 41/600 - (6%)

Human    15 LLALLLLLLAPLPPGAPPGADAYFPEERWSPESPLQAPRVLIALLARNAAHALPTTLGALERLRH 79
            |||.:|:.::        |.|    ||.:.     ::|.||||||.||.||.||..|..||:..:
  Fly    10 LLACILVCIS--------GQD----EEDYQ-----ESPTVLIALLVRNKAHILPMFLSYLEQQDY 57

Human    80 PRERTALWVATDHNMDNTSTVLREWLVAVKSLYHSVEWRPAEEPRSYPDEEGPKHWSDSRYEHVM 144
            |:||.|:|:..||:.|::..:||:||.....|||||.:....|.:|:.:...|..|..||::|::
  Fly    58 PKERIAIWLRCDHSNDDSIELLRQWLDNSGDLYHSVSYEFKPEEQSFVNGTSPYEWPASRFKHLI 122

Human   145 KLRQAALKSARDMWADYILFVDADNLILNPDTLSLLIAENKTVVAPMLDSRAAYSNFWCGMTSQG 209
            .|::.|.:..||:||||:.|:|||.|:.:.|:|.:|......:|||||.|.:.|||||||||...
  Fly   123 ALKEEAFQYGRDIWADYVFFLDADVLLTSKDSLKVLTRLQLPIVAPMLISESLYSNFWCGMTEDY 187

Human   210 YYKRTPAYIPIRKRDRRGCFAVPMVHSTFLIDLRKAASRNLAF-----------YPPHPDYTWSF 263
            ||:||..|..|....::|.|.|||||:..|:::...|.|||.|           ....|.|....
  Fly   188 YYRRTDEYKEIYHVKKQGSFPVPMVHTAVLVNMNHRAVRNLTFDRNKLVELQKSRQQEPLYDGPA 252

Human   264 DDIIVFAFSCKQAEVQMYVCNKEEYGFLPVPLRAHSTLQDEAESFMHVQLEVMVKHPPAEP---- 324
            |||||||.|...:.:.:::||...:|::..||....||..:.:..:::: .:||....|.|
  Fly   253 DDIIVFAISANSSGIPLHICNDITFGYILQPLEPGDTLDHDVQQLVNLK-SIMVNELGAVPPLLD 316

Human   325 --SRFISAPTKTPDKMGFDEVFMINLRRRQDRRERMLRALQAQEIECRLVEAVDGKAMNTSQVEA 387
              ......|.|:  |:..|.:|||||:||.:|||:|.|......||.....|||||.::|.::..
  Fly   317 YYKHLEKKPEKS--KLSLDRIFMINLKRRPERREKMERLFDEIGIEAEHFPAVDGKELSTERLLE 379

Human   388 LGIQMLPGYRDPYHGRPLTKGELGCFLSHYNIWKEVVDRGLQKSLVFEDDLRFEIFFKRRLMNLM 452
            :|::.||||.||||.|.:|.||:||||||||||..:|.:.|::.|:.|||:|||.:|::..:.::
  Fly   380 MGVRFLPGYEDPYHHRAMTMGEIGCFLSHYNIWVMMVRKQLKEVLILEDDIRFEPYFRQNAVRIL 444

Human   453 RDVEREGLDWDLIYVGRKRMQVEHPEKAVPRVRNLVEADYSYWTLAYVISLQGARKLLAAEPLSK 517
            ... |....:||||.||||:: |..|.||....|||.|.||||||.||||||||.|||||:||.|
  Fly   445 NQA-RNAAQYDLIYFGRKRLK-EESEPAVENADNLVHAGYSYWTLGYVISLQGALKLLAAKPLDK 507

Human   518 MLPVDEFLPVMFDKHPVSEYKAHFSLRNLHAFSVEPLLIYPTHYTGDDGYVSDTETSVVWNNEHV 582
            ::|||||||:|||:||...:...|..|||.|||..|||:||.:|||:.||:||||.|...:.|..
  Fly   508 LIPVDEFLPLMFDRHPNKTWTEAFPKRNLVAFSASPLLLYPIYYTGESGYISDTEDSQQISVETS 572

Human   583 KTDWDRAKSQKMREQ 597
            :....|.||.  |||
  Fly   573 EEGEARLKSD--REQ 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
COLGALT1	NP_078932.2	BcsA	42..>199	CDD:440828	62/156 (40%)
		COG3306	343..557	CDD:442535	114/213 (54%)
CG31915	NP_723087.1	Glyco_tranf_GTA_type	32..>146	CDD:472172	49/113 (43%)
		COG3306	334..555	CDD:442535	119/222 (54%)