Protein Alignment GALNT12 and Pgant9

DIOPT Version :9

• Sequence 1: NP_078918.3
• Gene: GALNT12 / 79695
• HGNCID: 19877
• Length: 581
• Species: Homo sapiens
• Sequence 2: NP_001097342.1
• Gene: Pgant9 / 246627
• FlyBaseID: FBgn0050463
• Length: 650
• Species: Drosophila melanogaster
• Alignment Length: 564
• Identity: 248/564 - (43%)
• Similarity: 338/564 - (59%)
• Gaps: 60/564 - (10%)

Human    37 LRAQRGAGAGAAEPGPPRTPRPGRREPVMPRPPVPAN---ALGARGEAVRL--QLQGEELRLQEE 96
            |:|:|.....|.:  |.:.|:...::.:.|    |||   ..|..|:.|||  ::..|..:..::
  Fly   111 LQAERMRKKAAEQ--PKKKPQEDSKKVIDP----PANFEENPGELGKPVRLPKEMSDEMKKAVDD 169

Human    97 SVRLHQINIYLSDRISLHRRLPERWNPLCKEKKYDYDNLPRTSVIIAFYNEAWSTLLRTVYSVLE 161
            ....:..|.|:||.||:||.||:..:..||::.....|||:|.|||.|:||||:.|||||:|||:
  Fly   170 GWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLD 234

Human   162 TSPDILLEEVILVDDYSDREHLKERLANELSGLPKVRLIRANKREGLVRARLLGASAARGDVLTF 226
            .||:.|:.::||||||||..|||.:|.:..:..|||::||..|||||:|||:|||:.|:..|||:
  Fly   235 RSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYPKVQIIRGQKREGLIRARILGANHAKSPVLTY 299

Human   227 LDCHCECHEGWLEPLLQRIHEEESAVVCPVIDVIDWNTFEY-LGNSGEPQIGGFDWRLVFTWHTV 290
            ||.||||.||||||||.||....:.|||||||||...|.|| ..:||...:|||||.|.|:||.|
  Fly   300 LDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNVGGFDWNLQFSWHPV 364

Human   291 PERERIRMQSPVDVIRSPTMAGGLFAVSKKYFEYLGSYDTGMEVWGGENLEFSFRIWQCGGVLET 355
            |||||.|..|..:.:.|||||||||::.:::|:.||:||:|.::|||||||.||:.|.|||.||.
  Fly   365 PERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEI 429

Human   356 HPCSHVGHVFPKQAPY----SRNKALANSVRAAEVWMDEFKELYYHR--NPRARLEPFGDVTERK 414
            .|||||||:|.|::||    ..|....||||.|||||||:.:.||||  |.:.   .:|||::|:
  Fly   430 VPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEVWMDEYSQYYYHRIGNDKG---DWGDVSDRR 491

Human   415 QLRDKLQCKDFKWFLETVYPELHVPEDRPGFFGMLQNKGLTDY----CFDYNPPDENQ--IVGHQ 473
            :||:.|:||.|||:|:.:||||.:|.|... .|.::|.|   |    |.|.....::|  .||
  Fly   492 KLRNDLKCKSFKWYLDNIYPELFIPGDSVA-HGEIRNLG---YGGRTCLDAPAGKKHQKKAVG-- 550

Human   474 VILYLCHGMGQNQFFEYTSQKEIRYNTHQPEGCIAVEAGMDTLIMHLCEE-------TAPENQKF 531
              .|.||..|.||::..:...|||    :.:.|:.. ||.|..:.. |..       |..||.|
  Fly   551 --TYPCHRQGGNQYWMLSKAGEIR----RDDSCLDY-AGKDVTLFG-CHGGKGNQFWTYRENTK- 606

Human   532 ILQEDGSLFHEQSKKCVQAARKESSDSFVPLLRDCTNS-DHQKW 574
                  .|.|..|.||:  |..||.|..  |:.:|:.| ..|:|
  Fly   607 ------QLHHGTSGKCL--AISESKDKL--LMEECSASLSRQQW 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GALNT12	NP_078918.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..67		3/23 (13%)
		WcaA	134..429	CDD:223539	172/301 (57%)
		Catalytic subdomain A	135..244		68/108 (63%)
		pp-GalNAc-T	139..433	CDD:133004	169/300 (56%)
		Catalytic subdomain B	304..366		37/61 (61%)
		Ricin_B_lectin	445..574	CDD:279046	40/142 (28%)
		RICIN	447..576	CDD:238092	41/142 (29%)
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	159/270 (59%)
		pp-GalNAc-T	213..510	CDD:133004	169/299 (57%)
		Ricin_B_lectin	521..640	CDD:279046	40/143 (28%)
		RICIN	523..642	CDD:238092	41/142 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152449
Domainoid	1	1.000	223	1.000	Domainoid score	I2581
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.721928	Normalized mean entropy	S3838
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153577at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.700