DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment VTCN1 and vtcn1

DIOPT Version :9

Sequence 1:	XP_011540445.2	Gene:	VTCN1 / 79679	HGNCID:	28873	Length:	332	Species:	Homo sapiens
Sequence 2:	XP_003199259.1	Gene:	vtcn1 / 100537676	ZFINID:	ZDB-GENE-070912-388	Length:	273	Species:	Danio rerio

Alignment Length:	266	Identity:	91/266 - (34%)
Similarity:	138/266 - (51%)	Gaps:	30/266 - (11%)

- Green bases have known domain annotations that are detailed below.

Human    43 SCGNVFFSAVRIRRSRKHSIISIIIILAGAIALI--IGFGISGR--HSITVTTVASAGNIGEDGI 103
            |.|.:.|.          |:|.:|::::|.|..|  |.|.:|..  .||:.|||   ||:.:|.:
Zfish     3 SIGQIIFG----------SMICLIVVMSGIIVFILAIAFSVSQGTVESISPTTV---GNLDDDVM 54

Human   104 LSCTFEPDI---KLSDIVIQWLKEGVLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASL 165
            |.|.|..:.   :.||:.|.|||:.|.|:|:|:|....:|..|:..|..|..:|.|.:..|||||
Zfish    55 LGCRFLSNTGNGQFSDVSITWLKDSVSGVVYEYKNKAAQLQTQNAQFSNRAQLFPDSISTGNASL 119

Human   166 RLKNVQLTDAGTYKCYIITSKGKGNANLEYKTGAFSMPEVNVDYNASSETLRCEAPRWFPQPTVV 230
            .|:|::|.|.|.|:|.:..:|..|.|.:..:..|||.|......|.|   |...|.:|||||.|.
Zfish   120 LLRNIKLEDDGVYRCTVNAAKVSGTAIVTLRVAAFSAPTFTELTNGS---LSAVATKWFPQPEVN 181

Human   231 WASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYN-VTINNTYSCMIENDIAKATGDIKVTESE 294
            |.:|..|..|    |:||| .|...: :.|.|:|.: |..|.||.|:|:|.:..|..:..||..:
Zfish   182 WYNQSGQILN----SSTSF-FNIAGI-IHVSSLLQDPVKENETYRCLIQNSLVVAVSEATVTAHK 240

Human   295 IKRRSH 300
            :.:.::
Zfish   241 VAQSTY 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VTCN1	XP_011540445.2	None
vtcn1	XP_003199259.1	IG_like	42..151	CDD:214653	41/111 (37%)
vtcn1	XP_003199259.1	Ig	51..152	CDD:299845	36/100 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194342148
Domainoid	1	1.000	47	1.000	Domainoid score	I36684
eggNOG	1	0.900	-	-		E1_2CFG9
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11627
Inparanoid	1	1.050	133	1.000	Inparanoid score	I11863
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG41458
OrthoDB	1	1.010	-	-		D1040668at2759
OrthoFinder	1	1.000	-	-		FOG0009749
OrthoInspector	1	1.000	-	-		oto41916
orthoMCL	1	0.900	-	-		OOG6_118973
Panther	1	1.100	-	-	LDO	PTHR24100
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7481
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	18	18.270